Compounds

ALA5271664

Name:
(+/-)-4'-(2-oxo-3-(3-(4-(trifluoromethyl)phenyl)ureido)piperidin-1-yl)-[1,1Show More⌵

Mol. Formula:
C26H23F3N4O3

M.W.:
496.49

Type:
---

AlogP:
4.79

Polar Surface Area:
104.53

HBA:
3

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA5271637

Name:
1-((7R,8S)-7-(2,6-difluoro-4-methoxyphenyl)-3,4,7,8-tetrahydro-6H-pyrrolo[2Show More⌵

Mol. Formula:
C20H19F3N4O3

M.W.:
420.39

Type:
---

AlogP:
3.05

Polar Surface Area:
75.19

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA5271505

Name:
N-(4-bromophenyl)-2-(5-(3-methoxybenzyl)-3,4-dimethyl-6-oxopyridazin-1(6H)-Show More⌵

Mol. Formula:
C22H22BrN3O3

M.W.:
456.34

Type:
---

AlogP:
3.86

Polar Surface Area:
73.22

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5271001

Name:
(+/-)-1-(1-(2'-fluoro-[1,1'-biphenyl]-4-yl)-2-oxopiperidin-3-yl)-3-(4-(trifShow More⌵

Mol. Formula:
C25H21F4N3O2

M.W.:
471.45

Type:
---

AlogP:
5.83

Polar Surface Area:
61.44

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA5270974

Name:
(S)-1-(4-chlorophenyl)-3-(2-(4-ethylphenyl)-1-(5-((2-hydroxyethyl)(methyl)aShow More⌵

Mol. Formula:
C22H26ClN5O3

M.W.:
443.94

Type:
---

AlogP:
3.82

Polar Surface Area:
103.52

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5270967

Name:
(S)-4'-(2-oxo-3-(3-(4-(trifluoromethyl)phenyl)ureido)piperidin-1-yl)-[1,1'-Show More⌵

Mol. Formula:
C26H22F3N3O4

M.W.:
497.47

Type:
---

AlogP:
5.39

Polar Surface Area:
98.74

HBA:
3

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5270733

Name:
(R)-N-((1-(4-(2-oxo-3-(3-(4-(trifluoromethyl)phenyl)ureido)piperidin-1-yl)pShow More⌵

Mol. Formula:
C24H27F3N4O4S

M.W.:
524.57

Type:
---

AlogP:
3.60

Polar Surface Area:
107.61

HBA:
4

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5270501

Name:
(R)-1-(1-(4-(2-oxa-6-azaspiro[3.3]heptan-6-yl)phenyl)-2-oxopiperidin-3-yl)-Show More⌵

Mol. Formula:
C23H24F3N5O3

M.W.:
475.47

Type:
---

AlogP:
3.25

Polar Surface Area:
86.80

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5270218

Name:
(R)-1-(1-(4-(4-methylpiperazin-1-yl)phenyl)-2-oxopiperidin-3-yl)-3-(4-(trifShow More⌵

Mol. Formula:
C24H28F3N5O2

M.W.:
475.52

Type:
---

AlogP:
3.77

Polar Surface Area:
67.92

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5269264

Name:
(R)-3-(4-cyanophenyl)-2-(3-(4-hydroxyphenyl)ureido)-N-((1-phenylcyclopropylShow More⌵

Mol. Formula:
C27H26N4O3

M.W.:
454.53

Type:
---

AlogP:
3.84

Polar Surface Area:
114.25

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA5268611

Name:
(R)-N-(4'-(2-oxo-3-(3-(6-(trifluoromethyl)pyridin-3-yl)ureido)piperidin-1-yShow More⌵

Mol. Formula:
C25H24F3N5O4S

M.W.:
547.56

Type:
---

AlogP:
4.46

Polar Surface Area:
120.50

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5267880

Name:
(R)-3-(4-cyanophenyl)-N-((1-(3-hydroxyphenyl)cyclopropyl)methyl)-2-(3-(4-meShow More⌵

Mol. Formula:
C28H28N4O4

M.W.:
484.56

Type:
---

AlogP:
3.85

Polar Surface Area:
123.48

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.37

DETAILS

ALA5267781

Name:
(R)-1-(1-(4-morpholinophenyl)-2-oxopiperidin-3-yl)-3-(4-(trifluoromethyl)phShow More⌵

Mol. Formula:
C23H25F3N4O3

M.W.:
462.47

Type:
---

AlogP:
3.86

Polar Surface Area:
73.91

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA5282707

Name:
(R)-4'-(2-oxo-3-(3-(4-(trifluoromethyl)phenyl)ureido)piperidin-1-yl)-[1,1'-Show More⌵

Mol. Formula:
C26H22F3N3O4

M.W.:
497.47

Type:
---

AlogP:
5.39

Polar Surface Area:
98.74

HBA:
3

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5282261

Name:
1-(4-cyanophenyl)-3-((3S,4R)-4-(6-fluoro-2,3-dihydrobenzofuran-5-yl)-2-oxopShow More⌵

Mol. Formula:
C20H17FN4O3

M.W.:
380.38

Type:
---

AlogP:
2.04

Polar Surface Area:
103.25

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5282051

Name:
(R)-1-(4-chlorophenyl)-3-(1-hydroxy-3-(4-methoxyphenyl)propan-2-yl)urea

Mol. Formula:
C17H19ClN2O3

M.W.:
334.80

Type:
---

AlogP:
3.07

Polar Surface Area:
70.59

HBA:
3

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5282050

Name:
(R)-3-(4-hydroxyphenyl)-2-(3-(4-methoxyphenyl)ureido)-N-((1-phenylcyclopropShow More⌵

Mol. Formula:
C27H29N3O4

M.W.:
459.55

Type:
---

AlogP:
3.98

Polar Surface Area:
99.69

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA5281870

Name:
(S)-1-(4-chlorophenyl)-3-(1-(5-(2-hydroxyethyl)-1,2,4-oxadiazol-3-yl)-2-(4-Show More⌵

Mol. Formula:
C20H21ClN4O4

M.W.:
416.87

Type:
---

AlogP:
3.37

Polar Surface Area:
109.51

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA5281612

Name:
1-[(3S,4R)-4-(4-chloro-2,6-difluoro-phenyl)-2-oxo-pyrrolidin-3-yl]-3-[1-(6-Show More⌵

Mol. Formula:
C20H19ClF2N4O2

M.W.:
420.85

Type:
---

AlogP:
2.89

Polar Surface Area:
83.12

HBA:
3

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5280794

Name:
(S)-3-(4-hydroxyphenyl)-2-(3-(4-methoxyphenyl)ureido)-N-((1-phenylcyclopropShow More⌵

Mol. Formula:
C27H29N3O4

M.W.:
459.55

Type:
---

AlogP:
3.98

Polar Surface Area:
99.69

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.39

DETAILS