Compounds

ALA4591205

Name:
(R)-1-(4-(1-aminopropan-2-yl)phenyl)-2-hydroxy-4,8-dimethylphenanthridin-6(Show More⌵

Mol. Formula:
C24H24N2O2

M.W.:
372.47

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.73

Polar Surface Area:
79.11

HBA:
3

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4588267

Name:
(R)-4-Chloro-1-(4-(1-(dimethylamino)ethyl)phenyl)-2,7-dihydroxyphenanthridiShow More⌵

Mol. Formula:
C23H21ClN2O3

M.W.:
408.89

4 activity values

4 unique targets

Type:
Unknown

AlogP:
5.04

Polar Surface Area:
76.56

HBA:
4

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4585042

Name:
(R)-1-(4-(1-(dimethylamino)propan-2-yl)phenyl)-2-hydroxy-4,8-dimethylphenanShow More⌵

Mol. Formula:
C26H28N2O2

M.W.:
400.52

4 activity values

4 unique targets

Type:
Unknown

AlogP:
5.34

Polar Surface Area:
56.33

HBA:
3

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4579248

Name:
(R)-1-(4-(1-aminopropan-2-yl)phenyl)-4-chloro-2,7-dihydroxyphenanthridin-6(Show More⌵

Mol. Formula:
C22H19ClN2O3

M.W.:
394.86

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.48

Polar Surface Area:
99.34

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA4573944

Name:
(R)-1-(4-(1-(dimethylamino)ethyl)phenyl)-2-hydroxy-4,8-dimethylphenanthridiShow More⌵

Mol. Formula:
C25H26N2O2

M.W.:
386.50

4 activity values

4 unique targets

Type:
Unknown

AlogP:
5.29

Polar Surface Area:
56.33

HBA:
3

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA4564624

Name:
(R)-1-(4-(1-aminopropan-2-yl)phenyl)-4-chloro-2-hydroxyphenanthridin-6(5H)-Show More⌵

Mol. Formula:
C22H19ClN2O2

M.W.:
378.86

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.77

Polar Surface Area:
79.11

HBA:
3

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4562809

Name:
(R)-1-(4-(1-(dimethylamino)ethyl)phenyl)-2,7-dihydroxy-4-methylphenanthridiShow More⌵

Mol. Formula:
C24H24N2O3

M.W.:
388.47

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.69

Polar Surface Area:
76.56

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4555026

Name:
(R)-4-Chloro-1-(4-(1-(dimethylamino)propan-2-yl)phenyl)-2,7-dihydroxyphenanShow More⌵

Mol. Formula:
C24H23ClN2O3

M.W.:
422.91

4 activity values

4 unique targets

Type:
Unknown

AlogP:
5.08

Polar Surface Area:
76.56

HBA:
4

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4552688

Name:
(R)-1-(4-(1-aminoethyl)phenyl)-2-methoxy-4-methylphenanthridin-6(5H)-one

Mol. Formula:
C23H22N2O2

M.W.:
358.44

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.69

Polar Surface Area:
68.11

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA4551832

Name:
(R)-1-(4-(1-(dimethylamino)propan-2-yl)phenyl)-2,7-dihydroxy-4-methylphenanShow More⌵

Mol. Formula:
C25H26N2O3

M.W.:
402.49

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.73

Polar Surface Area:
76.56

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4537653

Name:
1-(4-(1-(aminomethyl)cyclopropyl)phenyl)-2,7-dihydroxy-4-methylphenanthridiShow More⌵

Mol. Formula:
C24H22N2O3

M.W.:
386.45

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.06

Polar Surface Area:
99.34

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

OTS514 hydrochloride

Name:
(R)-9-(4-(1-aminopropan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinoliShow More⌵

Mol. Formula:
C21H21ClN2O2S

M.W.:
400.93

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.49

Polar Surface Area:
79.11

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4536593

Name:
(R)-1-(4-(1-aminopropan-2-yl)phenyl)-2-methoxy-4-methylphenanthridin-6(5H)-Show More⌵

Mol. Formula:
C24H24N2O2

M.W.:
372.47

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.73

Polar Surface Area:
68.11

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA4535960

Name:
(R)-1-(4-(1-aminoethyl)phenyl)-2-hydroxy-4,7-dimethylphenanthridin-6(5H)-onShow More⌵

Mol. Formula:
C23H22N2O2

M.W.:
358.44

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.69

Polar Surface Area:
79.11

HBA:
3

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4535216

Name:
(R)-1-(4-(1-aminoethyl)phenyl)-4-chloro-2,7-dihydroxyphenanthridin-6(5H)-onShow More⌵

Mol. Formula:
C21H17ClN2O3

M.W.:
380.83

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.43

Polar Surface Area:
99.34

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4534841

Name:
(R)-1-(4-(1-aminopropan-2-yl)phenyl)-7-fluoro-2-hydroxy-4-methylphenanthridShow More⌵

Mol. Formula:
C23H21FN2O2

M.W.:
376.43

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.56

Polar Surface Area:
79.11

HBA:
3

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA4534499

Name:
(R)-4-Chloro-1-(4-(1-(dimethylamino)propan-2-yl)phenyl)-2-hydroxyphenanthriShow More⌵

Mol. Formula:
C24H23ClN2O2

M.W.:
406.91

4 activity values

4 unique targets

Type:
Unknown

AlogP:
5.37

Polar Surface Area:
56.33

HBA:
3

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4528387

Name:
4-Chloro-1-(4-(1-((dimethylamino)methyl)cyclopropyl)phenyl)-2,7-dihydroxyphShow More⌵

Mol. Formula:
C25H23ClN2O3

M.W.:
434.92

4 activity values

4 unique targets

Type:
Unknown

AlogP:
5.01

Polar Surface Area:
76.56

HBA:
4

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4527920

Name:
(R)-1-(4-(1-aminoethyl)phenyl)-2-hydroxy-4-methylphenanthridin-6(5H)-one

Mol. Formula:
C22H20N2O2

M.W.:
344.41

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.38

Polar Surface Area:
79.11

HBA:
3

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA4519328

Name:
1-(4-(1-((dimethylamino)methyl)cyclopropyl)phenyl)-2,7-dihydroxy-4-methylphShow More⌵

Mol. Formula:
C26H26N2O3

M.W.:
414.51

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.66

Polar Surface Area:
76.56

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.42

DETAILS