Compounds

ALA5272293

Name:
3,5-difluoro-N-(3-(4-((methylamino)methyl)-1H-1,2,3-triazol-1-yl)phenyl)benShow More⌵

Mol. Formula:
C17H15F2N5O

M.W.:
343.34

Type:
---

AlogP:
2.52

Polar Surface Area:
71.84

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.75

DETAILS

ALA5271911

Name:
6-((5-fluoro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidinShow More⌵

Mol. Formula:
C23H26BFN6O3

M.W.:
464.31

Type:
---

AlogP:
---

Polar Surface Area:
---

HBA:
---

HBD:
---

#RO5 Violations:
na

#Rotatable Bonds:
---

Passes Ro3:
---

QED Weighted:
---

DETAILS

ALA5271682

Name:
6-((5-chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)Show More⌵

Mol. Formula:
C25H30BClN6O3

M.W.:
508.82

Type:
---

AlogP:
---

Polar Surface Area:
---

HBA:
---

HBD:
---

#RO5 Violations:
na

#Rotatable Bonds:
---

Passes Ro3:
---

QED Weighted:
---

DETAILS

ALA5270019

Name:
6-((5-chloro-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)aminShow More⌵

Mol. Formula:
C22H24BClN6O2

M.W.:
450.74

Type:
---

AlogP:
---

Polar Surface Area:
---

HBA:
---

HBD:
---

#RO5 Violations:
na

#Rotatable Bonds:
---

Passes Ro3:
---

QED Weighted:
---

DETAILS

ALA5269675

Name:
6-((5-chloro-2-((2-methoxyphenyl)amino)pyrimidin-4-yl)amino)benzo[c][1,2]oxShow More⌵

Mol. Formula:
C18H16BClN4O3

M.W.:
382.62

Type:
---

AlogP:
---

Polar Surface Area:
---

HBA:
---

HBD:
---

#RO5 Violations:
na

#Rotatable Bonds:
---

Passes Ro3:
---

QED Weighted:
---

DETAILS

ALA5269530

Name:

Mol. Formula:
C17H16FN5O2

M.W.:
341.35

Type:
---

AlogP:
2.16

Polar Surface Area:
80.55

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
---

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA5269433

Name:

Mol. Formula:
C20H20FN5O2

M.W.:
381.41

Type:
---

AlogP:
3.09

Polar Surface Area:
80.55

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
---

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5269028

Name:
7-((5-chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenShow More⌵

Mol. Formula:
C28H35BClN7O3

M.W.:
563.90

Type:
---

AlogP:
---

Polar Surface Area:
---

HBA:
---

HBD:
---

#RO5 Violations:
na

#Rotatable Bonds:
---

Passes Ro3:
---

QED Weighted:
---

DETAILS

ALA5268953

Name:
7-((5-chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)Show More⌵

Mol. Formula:
C25H30BClN6O3

M.W.:
508.82

Type:
---

AlogP:
---

Polar Surface Area:
---

HBA:
---

HBD:
---

#RO5 Violations:
na

#Rotatable Bonds:
---

Passes Ro3:
---

QED Weighted:
---

DETAILS

ALA5268149

Name:
3-((5-chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)Show More⌵

Mol. Formula:
C24H30BClN6O3

M.W.:
496.81

Type:
---

AlogP:
---

Polar Surface Area:
---

HBA:
---

HBD:
---

#RO5 Violations:
na

#Rotatable Bonds:
---

Passes Ro3:
---

QED Weighted:
---

DETAILS

ALA5281719

Name:

Mol. Formula:
C18H18FN5O2

M.W.:
355.37

Type:
---

AlogP:
2.38

Polar Surface Area:
80.55

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
---

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA5279319

Name:

Mol. Formula:
C21H20FN5O2

M.W.:
393.42

Type:
---

AlogP:
3.25

Polar Surface Area:
80.55

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA5279068

Name:

Mol. Formula:
C19H18FN5O2

M.W.:
367.38

Type:
---

AlogP:
2.70

Polar Surface Area:
80.55

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
---

Passes Ro3:
N

QED Weighted:
0.64

DETAILS

ALA5275923

Name:
6-((2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methylpyrimidinShow More⌵

Mol. Formula:
C24H29BN6O3

M.W.:
460.35

Type:
---

AlogP:
---

Polar Surface Area:
---

HBA:
---

HBD:
---

#RO5 Violations:
na

#Rotatable Bonds:
---

Passes Ro3:
---

QED Weighted:
---

DETAILS

ALA5275393

Name:
1,1'-((((5-(trifluoromethyl)pyrimidine-2,4-diyl)bis(azanediyl))bis(3-methoxShow More⌵

Mol. Formula:
C33H39F3N6O6

M.W.:
672.71

Type:
---

AlogP:
4.40

Polar Surface Area:
149.38

HBA:
10

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5274542

Name:

Mol. Formula:
C18H18FN5O2

M.W.:
355.37

Type:
---

AlogP:
2.55

Polar Surface Area:
80.55

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
---

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA5274362

Name:

Mol. Formula:
C20H20FN5O2

M.W.:
381.41

Type:
---

AlogP:
3.00

Polar Surface Area:
80.55

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
---

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5286953

Name:
6-((5-bromo-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-Show More⌵

Mol. Formula:
C23H26BBrN6O3

M.W.:
525.22

Type:
---

AlogP:
---

Polar Surface Area:
---

HBA:
---

HBD:
---

#RO5 Violations:
na

#Rotatable Bonds:
---

Passes Ro3:
---

QED Weighted:
---

DETAILS

ALA5286590

Name:
26-amino-55-fluoro-11,7-dimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,Show More⌵

Mol. Formula:
C20H17FN6O2

M.W.:
392.39

Type:
---

AlogP:
2.24

Polar Surface Area:
110.06

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
---

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5286542

Name:
3-((5-chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)Show More⌵

Mol. Formula:
C25H32BClN6O4

M.W.:
526.83

Type:
---

AlogP:
---

Polar Surface Area:
---

HBA:
---

HBD:
---

#RO5 Violations:
na

#Rotatable Bonds:
---

Passes Ro3:
---

QED Weighted:
---

DETAILS