Compounds

ALA5271452

Name:
1-(2,3-dimethyl-2H-indazol-5-yl)-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-1-Show More⌵

Mol. Formula:
C23H27N7O

M.W.:
417.52

Type:
---

AlogP:
3.59

Polar Surface Area:
80.87

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA5269831

Name:
1-(4-fluorobenzyl)-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-1-(3-methyl-1H-iShow More⌵

Mol. Formula:
C23H25FN6O

M.W.:
420.49

Type:
---

AlogP:
4.32

Polar Surface Area:
78.84

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5268584

Name:
1-(cyclohexylmethyl)-1-(2,3-dimethyl-2H-indazol-5-yl)-3-(3-(5-methyl-1H-imiShow More⌵

Mol. Formula:
C24H34N6O

M.W.:
422.58

Type:
---

AlogP:
4.57

Polar Surface Area:
67.98

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5268178

Name:
3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-1-(3-methyl-1H-indazol-6-yl)-1-(pyrShow More⌵

Mol. Formula:
C22H25N7O

M.W.:
403.49

Type:
---

AlogP:
3.58

Polar Surface Area:
91.73

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5268024

Name:
1-(1-(4-(2-aminopyridin-4-yl)butyl)-3-methyl-1H-indazol-6-yl)-3-(3-(5-methyShow More⌵

Mol. Formula:
C25H32N8O

M.W.:
460.59

Type:
---

AlogP:
4.06

Polar Surface Area:
115.68

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA5282127

Name:
1-cyclohexyl-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-1-(3-methyl-1H-indazolShow More⌵

Mol. Formula:
C22H30N6O

M.W.:
394.52

Type:
---

AlogP:
4.32

Polar Surface Area:
78.84

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5281802

Name:
3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-1-(3-methyl-1H-indazol-6-yl)-1-(1-mShow More⌵

Mol. Formula:
C22H31N7O

M.W.:
409.54

Type:
---

AlogP:
3.08

Polar Surface Area:
82.08

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5281584

Name:
1-(cyclopentylmethyl)-1-(1,3-dimethyl-1H-indazol-5-yl)-3-(3-(5-methyl-1H-imShow More⌵

Mol. Formula:
C23H32N6O

M.W.:
408.55

Type:
---

AlogP:
4.18

Polar Surface Area:
67.98

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5281059

Name:
1-(3-methyl-1-(2-(4-methylpiperazin-1-yl)ethyl)-1H-indazol-6-yl)-3-(3-(5-meShow More⌵

Mol. Formula:
C23H34N8O

M.W.:
438.58

Type:
---

AlogP:
2.31

Polar Surface Area:
83.25

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5279792

Name:
1-cyclohexyl-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-1-(3-methyl-1H-indazolShow More⌵

Mol. Formula:
C22H30N6O

M.W.:
394.52

Type:
---

AlogP:
4.32

Polar Surface Area:
78.84

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5277817

Name:
1-(2,3-dimethyl-2H-indazol-5-yl)-1-(4-fluorobenzyl)-3-(3-(5-methyl-1H-imidaShow More⌵

Mol. Formula:
C24H27FN6O

M.W.:
434.52

Type:
---

AlogP:
4.33

Polar Surface Area:
67.98

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5277759

Name:
1-(1,3-dimethyl-1H-indazol-5-yl)-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-1-Show More⌵

Mol. Formula:
C23H27N7O

M.W.:
417.52

Type:
---

AlogP:
3.59

Polar Surface Area:
80.87

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA5276913

Name:
1-(2,3-dimethyl-2H-indazol-6-yl)-1-(4-fluorobenzyl)-3-(3-(5-methyl-1H-imidaShow More⌵

Mol. Formula:
C24H27FN6O

M.W.:
434.52

Type:
---

AlogP:
4.33

Polar Surface Area:
67.98

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5276086

Name:
1-(1,3-dimethyl-1H-indazol-6-yl)-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)ureShow More⌵

Mol. Formula:
C17H22N6O

M.W.:
326.40

Type:
---

AlogP:
2.60

Polar Surface Area:
76.77

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5275966

Name:
1-(4-fluorobenzyl)-1-(1H-indazol-6-yl)-3-(3-(5-methyl-1H-imidazol-1-yl)propShow More⌵

Mol. Formula:
C22H23FN6O

M.W.:
406.46

Type:
---

AlogP:
4.01

Polar Surface Area:
78.84

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5275094

Name:
1-(3-(5-methyl-1H-imidazol-1-yl)propyl)-3-(3-methyl-1H-indazol-5-yl)urea

Mol. Formula:
C16H20N6O

M.W.:
312.38

Type:
---

AlogP:
2.59

Polar Surface Area:
87.63

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5274513

Name:
1-(2,3-dimethyl-2H-indazol-6-yl)-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-1-Show More⌵

Mol. Formula:
C23H27N7O

M.W.:
417.52

Type:
---

AlogP:
3.59

Polar Surface Area:
80.87

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA5273104

Name:
1-cyclohexyl-1-(1,3-dimethyl-1H-indazol-5-yl)-3-(3-(5-methyl-1H-imidazol-1-Show More⌵

Mol. Formula:
C23H32N6O

M.W.:
408.55

Type:
---

AlogP:
4.33

Polar Surface Area:
67.98

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA5286870

Name:
1-(cyclopentylmethyl)-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-1-(3-methyl-1Show More⌵

Mol. Formula:
C22H30N6O

M.W.:
394.52

Type:
---

AlogP:
4.17

Polar Surface Area:
78.84

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5286536

Name:
1-(1,3-dimethyl-1H-indazol-6-yl)-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-1-Show More⌵

Mol. Formula:
C23H27N7O

M.W.:
417.52

Type:
---

AlogP:
3.59

Polar Surface Area:
80.87

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.47

DETAILS