Compounds

Type:
---

AlogP:
2.79

Polar Surface Area:
102.02

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5207954

Name:
N-((1r,4r)-4-(2-Methoxyethoxy)cyclohexyl)-5-(1H-pyrazol-4-yl)-1H-indole-7-cShow More⌵

Mol. Formula:
C21H26N4O3

M.W.:
382.46

Type:
---

AlogP:
3.26

Polar Surface Area:
92.03

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA5207454

Name:
N-((1r,3r)-3-(2-Methoxyethoxy)cyclobutyl)-6-(thiazol-5-yl)-1H-indole-4-carbShow More⌵

Mol. Formula:
C19H21N3O3S

M.W.:
371.46

Type:
---

AlogP:
3.22

Polar Surface Area:
76.24

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5207349

Name:
N-((1r,4r)-4-(3-Methoxypropoxy)cyclohexyl)-6-(thiazol-5-yl)-1H-indole-4-carShow More⌵

Mol. Formula:
C22H27N3O3S

M.W.:
413.54

Type:
---

AlogP:
4.39

Polar Surface Area:
76.24

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5207157

Name:
N-(1r,4r)-4-(2-Methoxyethoxy)cyclohexyl)-6-(thiazol-5-yl)-1H-indole-4-carboShow More⌵

Mol. Formula:
C21H25N3O3S

M.W.:
399.52

Type:
---

AlogP:
4.00

Polar Surface Area:
76.24

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5205975

Name:
5-(1H-Imidazol-1-yl)-N-((1r,4r)-4-(2-methoxyethoxy)cyclohexyl)-1H-indazole-Show More⌵

Mol. Formula:
C20H25N5O3

M.W.:
383.45

Type:
---

AlogP:
2.45

Polar Surface Area:
94.06

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5205105

Name:
1-Ethyl-N-((1r,4r)-4-(2-methoxyethoxy)cyclohexyl)-6-(thiazol-5-yl)-1H-pyrroShow More⌵

Mol. Formula:
C22H28N4O3S

M.W.:
428.56

Type:
---

AlogP:
3.88

Polar Surface Area:
78.27

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA5204685

Name:
N-((1r,4r)-4-(2-Methoxyethoxy)cyclohexyl-5-(thiazol-5-yl)-1H-pyrrolo(3,2-b)Show More⌵

Mol. Formula:
C20H24N4O3S

M.W.:
400.50

Type:
---

AlogP:
3.39

Polar Surface Area:
89.13

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5204215

Name:
N-((1r,4r)-4-(2-Methoxyethoxy)cyclohexyl)-5-(pyridin-2-yl)-1H-indole-7-carbShow More⌵

Mol. Formula:
C23H27N3O3

M.W.:
393.49

Type:
---

AlogP:
3.93

Polar Surface Area:
76.24

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5202189

Name:
N-((1S,4S)-4-(2-Methoxyethoxy)cyclohexyl)-6-(thlazol-5-yl)-1H-indole-4-carbShow More⌵

Mol. Formula:
C21H25N3O3S

M.W.:
399.52

Type:
---

AlogP:
4.00

Polar Surface Area:
76.24

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5200939

Name:
N-((1r,4r)-4-(2-Methoxyethoxy)cyclohexyl)-6-(thiazol-5-yl)-[1,2,4]triazolo[Show More⌵

Mol. Formula:
C19H23N5O3S

M.W.:
401.49

Type:
---

AlogP:
2.56

Polar Surface Area:
90.64

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5198750

Name:
5-(1H-imidazol-1-yl)-N-((1r,4r)-4-(2-methoxyethoxy)cyclohexyl)3-(trifluoromShow More⌵

Mol. Formula:
C22H25F3N4O3

M.W.:
450.46

Type:
---

AlogP:
4.08

Polar Surface Area:
81.17

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5198749

Name:
N-((1r,4r)-4-(2-Methoxyethoxy)cyclohexyl)-5-phenyl-1H-indole-7-carboxamide

Mol. Formula:
C24H28N2O3

M.W.:
392.50

Type:
---

AlogP:
4.54

Polar Surface Area:
63.35

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA5197813

Name:
5-(1H-Imidazol-1-yl)-N7-((1r,4r)-4-(2-methoxyethoxy)cyclohexyl)-1H-indole-3Show More⌵

Mol. Formula:
C22H27N5O4

M.W.:
425.49

Type:
---

AlogP:
2.16

Polar Surface Area:
124.26

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5196986

Name:
3-Cyano-N-((1r,4r)-4-(2-methoxyethoxy)cyclohexyl)-6-(thiazol-5-yl)-1H-indolShow More⌵

Mol. Formula:
C22H24N4O3S

M.W.:
424.53

Type:
---

AlogP:
3.87

Polar Surface Area:
100.03

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA5195818

Name:
N-[[(1r,4r)-4-(2-methoxyethoxy)cyclohexyl]methyl]-6-thiazol-5-yl-1H-indole-Show More⌵

Mol. Formula:
C22H27N3O3S

M.W.:
413.54

Type:
---

AlogP:
4.24

Polar Surface Area:
76.24

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5195341

Name:
3-(1-Hydroxyethyl)-5-(1H-imidazol-1-yl)-N-((1r,4r)-4-(2-methoxyethoxy)cycloShow More⌵

Mol. Formula:
C23H30N4O4

M.W.:
426.52

Type:
---

AlogP:
3.11

Polar Surface Area:
101.40

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5194298

Name:
5-(1H-Imidazol-1-yl)-N7-((1r,4r)-4-(2-methoxyethoxy)cyclohexyl)-N3,N3-dimetShow More⌵

Mol. Formula:
C24H31N5O4

M.W.:
453.54

Type:
---

AlogP:
2.76

Polar Surface Area:
101.48

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5192931

Name:
7-Fluoro-N-((1r,4r)-4-(2-methoxyethoxy)cyclohexyl)-6-(thiazol-5-yl)-1H-indoShow More⌵

Mol. Formula:
C21H24FN3O3S

M.W.:
417.51

Type:
---

AlogP:
4.13

Polar Surface Area:
76.24

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5191920

Name:
N-((1r,4r)-4-(2-Methoxyethoxy)cyclohexyl)-1-methyl-6-(thiazol-5-yl)-1H-indoShow More⌵

Mol. Formula:
C22H27N3O3S

M.W.:
413.54