Compounds

ALA5272665

Name:
tert-butyl 4-(2-((4-(benzo[d]thiazol-5-yl)-5-fluoropyrimidin-2-yl)amino)pyrShow More⌵

Mol. Formula:
C25H25FN8O3S

M.W.:
536.59

Type:
---

AlogP:
4.12

Polar Surface Area:
126.33

HBA:
10

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA5272422

Name:
tert-butyl 4-(6-((4-(benzo[d]thiazol-5-yl)-5-fluoropyrimidin-2-yl)amino)nicShow More⌵

Mol. Formula:
C26H26FN7O3S

M.W.:
535.61

Type:
---

AlogP:
4.72

Polar Surface Area:
113.44

HBA:
9

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5272300

Name:
(5-((4-(benzo[d]thiazol-5-yl)-5-fluoropyrimidin-2-yl)amino)pyridin-2-yl)(4-Show More⌵

Mol. Formula:
C23H22FN7OS

M.W.:
463.54

Type:
---

AlogP:
3.81

Polar Surface Area:
87.14

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5272161

Name:
(E)-7'-bromo-3-(hydroxyimino)-2'-oxo-[2,3'-biindoline]-5-carboxylic acid

Mol. Formula:
C17H12BrN3O4

M.W.:
402.20

Type:
---

AlogP:
2.86

Polar Surface Area:
111.02

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5271186

Name:
1-(4-(6-((4-(benzo[d]thiazol-5-yl)-5-fluoropyrimidin-2-yl)amino)nicotinoyl)Show More⌵

Mol. Formula:
C23H20FN7O2S

M.W.:
477.53

Type:
---

AlogP:
3.34

Polar Surface Area:
104.21

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5270999

Name:
tert-butyl 4-(6-((4-(benzo[d]thiazol-5-yl)-5-methylpyrimidin-2-yl)amino)nicShow More⌵

Mol. Formula:
C27H29N7O3S

M.W.:
531.64

Type:
---

AlogP:
4.89

Polar Surface Area:
113.44

HBA:
9

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5281152

Name:
4-(benzo[d]thiazol-5-yl)-N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-Show More⌵

Mol. Formula:
C23H24FN7S

M.W.:
449.56

Type:
---

AlogP:
4.17

Polar Surface Area:
70.07

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA5280825

Name:
(6-((4-(benzo[d]thiazol-5-yl)-5-fluoropyrimidin-2-yl)amino)pyridin-3-yl)(4-Show More⌵

Mol. Formula:
C27H22FN7OS

M.W.:
511.59

Type:
---

AlogP:
4.99

Polar Surface Area:
87.14

HBA:
8

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA5280350

Name:
(6-((4-(benzo[d]thiazol-5-yl)pyrimidin-2-yl)amino)pyridin-3-yl)(piperazin-1Show More⌵

Mol. Formula:
C21H20ClN7OS

M.W.:
453.96

Type:
---

AlogP:
2.94

Polar Surface Area:
95.93

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5279534

Name:
(6-((4-(benzo[d]thiazol-5-yl)-5-methylpyrimidin-2-yl)amino)pyridin-3-yl)(4-Show More⌵

Mol. Formula:
C24H25N7OS

M.W.:
459.58

Type:
---

AlogP:
3.98

Polar Surface Area:
87.14

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5279010

Name:
4-(benzo[d]thiazol-5-yl)-5-fluoro-N-(5-(piperazin-1-ylmethyl)pyridin-2-yl)pShow More⌵

Mol. Formula:
C21H21ClFN7S

M.W.:
457.97

Type:
---

AlogP:
3.44

Polar Surface Area:
78.86

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5278493

Name:
tert-butyl 4-(5-((4-(benzo[d]thiazol-5-yl)-5-fluoropyrimidin-2-yl)amino)picShow More⌵

Mol. Formula:
C26H26FN7O3S

M.W.:
535.61

Type:
---

AlogP:
4.72

Polar Surface Area:
113.44

HBA:
9

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5278425

Name:
(6-((4-(benzo[d]thiazol-5-yl)-5-methylpyrimidin-2-yl)amino)pyridin-3-yl)(piShow More⌵

Mol. Formula:
C22H22ClN7OS

M.W.:
467.99

Type:
---

AlogP:
3.25

Polar Surface Area:
95.93

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5277818

Name:
(6-((4-(benzo[d]thiazol-5-yl)-5-fluoropyrimidin-2-yl)amino)pyridin-3-yl)(4-Show More⌵

Mol. Formula:
C23H22FN7OS

M.W.:
463.54

Type:
---

AlogP:
3.81

Polar Surface Area:
87.14

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5277043

Name:
(4-(6-((4-(benzo[d]thiazol-5-yl)-5-fluoropyrimidin-2-yl)amino)nicotinoyl)piShow More⌵

Mol. Formula:
C25H22FN7O2S

M.W.:
503.56

Type:
---

AlogP:
3.73

Polar Surface Area:
104.21

HBA:
8

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5276852

Name:
4-(benzo[d]thiazol-5-yl)-N-(5-((4-isopropylpiperazin-1-yl)methyl)pyridin-2-Show More⌵

Mol. Formula:
C25H29N7S

M.W.:
459.62

Type:
---

AlogP:
4.73

Polar Surface Area:
70.07

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5274593

Name:
4-(benzo[d]thiazol-5-yl)-N-(5-(piperazin-1-ylmethyl)pyridin-2-yl)pyrimidin-Show More⌵

Mol. Formula:
C21H22ClN7S

M.W.:
439.98

Type:
---

AlogP:
3.30

Polar Surface Area:
78.86

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5274485

Name:
4-(benzo[d]thiazol-5-yl)-5-methoxy-N-(5-(piperazin-1-ylmethyl)pyridin-2-yl)Show More⌵

Mol. Formula:
C22H24ClN7OS

M.W.:
470.00

Type:
---

AlogP:
3.31

Polar Surface Area:
88.09

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5274190

Name:
tert-butyl 4-((6-((4-(benzo[d]thiazol-5-yl)pyrimidin-2-yl)amino)pyridin-3-yShow More⌵

Mol. Formula:
C26H29N7O2S

M.W.:
503.63

Type:
---

AlogP:
4.94

Polar Surface Area:
96.37

HBA:
9

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA5273713

Name:
tert-butyl 4-(6-((4-(benzo[d]thiazol-5-yl)pyrimidin-2-yl)amino)nicotinoyl)pShow More⌵

Mol. Formula:
C26H27N7O3S

M.W.:
517.62

Type:
---

AlogP:
4.58

Polar Surface Area:
113.44

HBA:
9

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.42

DETAILS