Compounds

Type:
Unknown

AlogP:
3.84

Polar Surface Area:
32.34

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA4588071

Name:
(2,6-Dichlorophenyl)-(8-isopropyl-1-oxa-4,8-diazaspiro[4.5]decan-4-yl)methaShow More⌵

Mol. Formula:
C17H22Cl2N2O2

M.W.:
357.28

Type:
Unknown

AlogP:
3.67

Polar Surface Area:
32.78

HBA:
3

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA4578817

Name:
(2,6-Dichlorophenyl)-(4-isopropylpiperazin-1-yl)methanone

Mol. Formula:
C14H18Cl2N2O

M.W.:
301.22

Type:
Unknown

AlogP:
3.16

Polar Surface Area:
23.55

HBA:
2

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.84

DETAILS

ALA4577797

Name:
2-Chloro-N-(1-isopropylpiperidin-4-yl)-4-nitrobenzamide

Mol. Formula:
C15H20ClN3O3

M.W.:
325.80

Type:
Unknown

AlogP:
2.85

Polar Surface Area:
75.48

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA4566482

Name:
2,6-Dichloro-N-(1-isopropylpiperidin-3-yl)benzamide

Mol. Formula:
C15H20Cl2N2O

M.W.:
315.24

Type:
Unknown

AlogP:
3.60

Polar Surface Area:
32.34

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.92

DETAILS

ALA4562905

Name:
(R/S)-2,6-Dichloro-N-(3,3-difluoro-1-isopropylpiperidin-4-yl)benzamide

Mol. Formula:
C15H18Cl2F2N2O

M.W.:
351.22

Type:
Unknown

AlogP:
3.84

Polar Surface Area:
32.34

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.90

DETAILS

ALA4559323

Name:
2-Chloro-N-(1-cyclohexylpiperidin-4-yl)-4-(trifluoromethyl)benzamide

Mol. Formula:
C19H24ClF3N2O

M.W.:
388.86

Type:
Unknown

AlogP:
4.89

Polar Surface Area:
32.34

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA4558751

Name:
2-Chloro-N-(1-isopropylpiperidin-4-yl)-4-(trifluoromethyl)benzamide

Mol. Formula:
C16H20ClF3N2O

M.W.:
348.80

6 activity values

Type:
Unknown

AlogP:
3.96

Polar Surface Area:
32.34

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.90

DETAILS

ALA4553080

Name:
2,6-Dichloro-N-(1-isopropylazepan-4-yl)benzamide

Mol. Formula:
C16H22Cl2N2O

M.W.:
329.27

Type:
Unknown

AlogP:
3.99

Polar Surface Area:
32.34

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA4551420

Name:
(R/S)-2,6-Dichloro-N-(1-isopropyl-4-methylpiperidin-4-yl)benzamide

Mol. Formula:
C16H22Cl2N2O

M.W.:
329.27

Type:
Unknown

AlogP:
3.99

Polar Surface Area:
32.34

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA4531999

Name:
2-Chloro-N-(1-isobutylpiperidin-4-yl)-4-(trifluoromethyl)benzamide

Mol. Formula:
C17H22ClF3N2O

M.W.:
362.82

Type:
Unknown

AlogP:
4.21

Polar Surface Area:
32.34

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.87

DETAILS

ALA4530857

Name:
2,4-Dichloro-N-(1-isopropylpiperidin-4-yl)benzenesulfonamide

Mol. Formula:
C14H20Cl2N2O2S

M.W.:
351.30

Type:
Unknown

AlogP:
3.14

Polar Surface Area:
49.41

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA4529862

Name:
2,6-Dichloro-N-(1-isopropylpyrrolidin-3-yl)benzamide

Mol. Formula:
C14H18Cl2N2O

M.W.:
301.22

Type:
Unknown

AlogP:
3.21

Polar Surface Area:
32.34

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.93

DETAILS

ALA4527195

Name:
2,6-Dichloro-N-((3S,4S)-3-fluoro-1-isopropylpiperidin-4-yl)benzamide

Mol. Formula:
C15H19Cl2FN2O

M.W.:
333.23

Type:
Unknown

AlogP:
3.54

Polar Surface Area:
32.34

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.92

DETAILS

ALA4464455

Name:
3-Chloro-N-(1-isopropylpiperidin-4-yl)picolinamide

Mol. Formula:
C14H20ClN3O

M.W.:
281.79

Type:
Unknown

AlogP:
2.34

Polar Surface Area:
45.23

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
Y

QED Weighted:
0.92

DETAILS

ALA4462534

Name:
2,6-Dichloro-N-(1-(oxetan-3-yl)piperidin-4-yl)benzamide

Mol. Formula:
C15H18Cl2N2O2

M.W.:
329.23

Type:
Unknown

AlogP:
2.59

Polar Surface Area:
41.57

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.93

DETAILS

ALA4461234

Name:
2-Chloro-N-((3S,4S)-3-fluoro-1-isopropylpiperidin-4-yl)-4-(trifluoromethyl)Show More⌵

Mol. Formula:
C16H19ClF4N2O

M.W.:
366.79

Type:
Unknown

AlogP:
3.91

Polar Surface Area:
32.34

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA4456793

Name:
3,5-Dichloro-N-(1-isopropylpiperidin-4-yl)picolinamide

Mol. Formula:
C14H19Cl2N3O

M.W.:
316.23

Type:
Unknown

AlogP:
2.99

Polar Surface Area:
45.23

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.93

DETAILS

ALA4454657

Name:
2,6-Dichloro-N-(3-isopropyl-3-azabicyclo[3.1.0]hexan-6-yl)benzamide

Mol. Formula:
C15H18Cl2N2O

M.W.:
313.23

Type:
Unknown

AlogP:
3.06

Polar Surface Area:
32.34

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.93

DETAILS

ALA4454632

Name:
2,6-Dichloro-N-((1-isopropylpiperidin-4-yl)methyl)benzamide

Mol. Formula:
C16H22Cl2N2O

M.W.:
329.27