Compounds

ALA5267358

Name:
N-(4-(4-fluoro-2-methoxyphenyl)pyridazin-3-yl)-N-methyl-3-(methylsulfonyl)-Show More⌵

Mol. Formula:
C21H17F4N3O4S

M.W.:
483.44

Type:
---

AlogP:
3.99

Polar Surface Area:
89.46

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5266920

Name:
N-(2-fluorophenyl)-2-((3R,5R)-1-isobutyl-5-(3-(methylamino)phenyl)-2-oxo-1,Show More⌵

Mol. Formula:
C28H30FN3O3

M.W.:
475.56

Type:
---

AlogP:
5.37

Polar Surface Area:
70.67

HBA:
4

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5266085

Name:
(3,5-bis(trifluoromethyl)phenyl)(1-phenyl-4,5-dihydro-1H-pyrrolo[1,2-a][1,4Show More⌵

Mol. Formula:
C23H18F6N2O

M.W.:
452.40

Type:
---

AlogP:
6.16

Polar Surface Area:
25.24

HBA:
2

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5282482

Name:
2-(4-bromophenyl)-N-((2-(thiophen-3-yl)-1,7-naphthyridin-3-yl)methyl)ethan-Show More⌵

Mol. Formula:
C21H18BrN3S

M.W.:
424.37

Type:
---

AlogP:
5.45

Polar Surface Area:
37.81

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5281639

Name:
5-((R)-1-(hydroxyimino)-3-(4-(methylsulfonyl)phenyl)-3-(o-tolyl)propyl)-1-mShow More⌵

Mol. Formula:
C23H28N2O4S

M.W.:
428.55

Type:
---

AlogP:
3.62

Polar Surface Area:
87.04

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5280905

Name:
N-(2-chloro-4-fluorophenyl)-N-(2-cyano-4-fluorophenyl)-2-(isoquinolin-5-yloShow More⌵

Mol. Formula:
C24H14ClF2N3O2

M.W.:
449.84

Type:
---

AlogP:
5.78

Polar Surface Area:
66.22

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA5280567

Name:
(3-(2,5-dichlorophenoxy)pyridin-4-yl)(3,4-dihydroquinolin-1(2H)-yl)methanonShow More⌵

Mol. Formula:
C21H16Cl2N2O2

M.W.:
399.28

Type:
---

AlogP:
5.77

Polar Surface Area:
42.43

HBA:
3

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA5278768

Name:
3-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-4-(2,4-difluorophenyl)-5-[(3,Show More⌵

Mol. Formula:
C24H19ClF3N3O2S

M.W.:
505.95

Type:
---

AlogP:
6.24

Polar Surface Area:
49.17

HBA:
6

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA5277271

Name:
1-(6-(thiophen-3-yl)thieno[2,3-b]pyridin-5-yl)-N-(4-(trifluoromethyl)benzylShow More⌵

Mol. Formula:
C20H15F3N2S2

M.W.:
404.48

Type:
---

AlogP:
6.33

Polar Surface Area:
24.92

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5276894

Name:
5-(3,5-bis(trifluoromethyl)phenyl)-4-((4-(2-fluorophenyl)pyridin-3-yl)methyShow More⌵

Mol. Formula:
C26H16F7N3O2

M.W.:
535.42

Type:
---

AlogP:
7.41

Polar Surface Area:
50.86

HBA:
5

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA5274626

Name:
5-(3,5-bis(trifluoromethyl)phenyl)-4-((4-(2-fluorophenyl)pyridin-3-yl)methyShow More⌵

Mol. Formula:
C28H18F7N3O

M.W.:
545.46

Type:
---

AlogP:
7.82

Polar Surface Area:
37.72

HBA:
4

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5274061

Name:
3-(2-(3,4-dimethoxyphenyl)propan-2-yl)-4-(4-fluorophenyl)-5-((2-(4-(4-(thioShow More⌵

Mol. Formula:
C34H32FN5O3S2

M.W.:
641.79

Type:
---

AlogP:
7.83

Polar Surface Area:
76.22

HBA:
10

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.10

DETAILS

ALA5273628

Name:
(3,5-bis(trifluoromethyl)phenyl)(6-phenyl-2,3-dihydropyrido[3,2-f][1,4]oxazShow More⌵

Mol. Formula:
C23H16F6N2O2

M.W.:
466.38

Type:
---

AlogP:
5.82

Polar Surface Area:
42.43

HBA:
3

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5291142

Name:
4-((4-(2,6-difluorophenyl)pyridin-3-yl)methyl)-3-(furan-2-yl)-5-phenyl-4,5-Show More⌵

Mol. Formula:
C24H17F2N3O2

M.W.:
417.42

Type:
---

AlogP:
5.51

Polar Surface Area:
50.86

HBA:
5

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5290871

Name:
(1R,5S)-3-(4-((R,Z)-1-(2,4-difluorophenyl)-3-(hydroxyimino)-3-(2-methylpyriShow More⌵

Mol. Formula:
C28H26F2N2O3

M.W.:
476.52

Type:
---

AlogP:
5.89

Polar Surface Area:
82.78

HBA:
4

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA5286933

Name:
3-((2-oxa-6-azaspiro[3.3]heptan-6-yl)sulfonyl)-N-(4-(4-fluoro-2-methoxyphenShow More⌵

Mol. Formula:
C26H23F4N3O5S

M.W.:
565.55

Type:
---

AlogP:
4.21

Polar Surface Area:
89.04

HBA:
6

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5286375

Name:
5-((1-(2-chloro-4-fluorophenyl)-1H-benzo[d]imidazol-2-yl)methoxy)isoquinoliShow More⌵

Mol. Formula:
C23H15ClFN3O

M.W.:
403.84

Type:
---

AlogP:
5.95

Polar Surface Area:
39.94

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.37

DETAILS

ALA5285528

Name:
3-((2-chloro-6-fluorobenzyl)thio)-5-(p-tolyl)thiazolo[2,3-c][1,2,4]triazole

Mol. Formula:
C18H13ClFN3S2

M.W.:
389.91

Type:
---

AlogP:
5.85

Polar Surface Area:
30.19

HBA:
5

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA5284578

Name:
2-(3-((1-(4-(3-chloro-2-methylphenoxy)butanoyl)-1,2,3,4-tetrahydroquinolin-Show More⌵

Mol. Formula:
C30H33ClN2O6S

M.W.:
585.12

Type:
---

AlogP:
5.19

Polar Surface Area:
113.01

HBA:
5

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5284434

Name:
(R)-5-(2-chloro-3,5-bis(trifluoromethyl)phenyl)-4-((4-(2,6-difluorophenyl)pShow More⌵

Mol. Formula:
C26H14ClF8N3O2

M.W.:
587.85

Type:
---

AlogP:
8.20

Polar Surface Area:
50.86

HBA:
5

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.22

DETAILS