Compounds

ALA4795791

Name:
(R)-1-(5-((1-(2,5-difluorophenyl)ethyl)(methyl)amino)pyrazolo[1,5-a]pyrimidShow More⌵

Mol. Formula:
C22H20F2N6O2

M.W.:
438.44

3 activity values

3 unique targets

Type:
Unknown

AlogP:
4.55

Polar Surface Area:
94.79

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4791453

Name:
N-(5-(((R)-1-(2,5-difluorophenyl)ethyl)(methyl)amino)pyrazolo[1,5-a]pyrimidShow More⌵

Mol. Formula:
C22H26F2N6O2

M.W.:
444.49

3 activity values

3 unique targets

Type:
Unknown

AlogP:
3.44

Polar Surface Area:
86.00

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA4788418

Name:
3-(5-(((R)-1-(2,5-difluorophenyl)ethyl)(methyl)amino)pyrazolo[1,5-a]pyrimidShow More⌵

Mol. Formula:
C23H22F2N6O3

M.W.:
468.46

3 activity values

3 unique targets

Type:
Unknown

AlogP:
2.12

Polar Surface Area:
103.07

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4787769

Name:
1-(5-(((R)-1-(2,5-difluorophenyl)ethyl)(methyl)amino)pyrazolo[1,5-a]pyrimidShow More⌵

Mol. Formula:
C20H24F2N6O2

M.W.:
418.45

3 activity values

3 unique targets

Type:
Unknown

AlogP:
3.10

Polar Surface Area:
94.79

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA4784645

Name:
(S)-N-(5-((R)-1-(2,5-difluorophenyl)ethylamino)pyrazolo[1,5-a]pyrimidin-3-yShow More⌵

Mol. Formula:
C19H20F2N6O2

M.W.:
402.41

3 activity values

3 unique targets

Type:
Unknown

AlogP:
2.78

Polar Surface Area:
94.79

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA4783042

Name:
(R)-3-(5-(1-(2,5-difluorophenyl)ethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)-1Show More⌵

Mol. Formula:
C21H26F2N6O

M.W.:
416.48

3 activity values

3 unique targets

Type:
Unknown

AlogP:
4.83

Polar Surface Area:
74.56

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA4782487

Name:
(R)-N-(5-((1-(2,5-difluorophenyl)ethyl)(methyl)amino)pyrazolo[1,5-a]pyrimidShow More⌵

Mol. Formula:
C21H25F2N7O

M.W.:
429.48

3 activity values

3 unique targets

Type:
Unknown

AlogP:
2.98

Polar Surface Area:
69.01

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA4780959

Name:
(R)-1-(5-(1-(2,5-difluorophenyl)ethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)-3Show More⌵

Mol. Formula:
C21H18F2N6O2

M.W.:
424.41

3 activity values

3 unique targets

Type:
Unknown

AlogP:
4.53

Polar Surface Area:
103.58

HBA:
6

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.35

DETAILS

ALA4778629

Name:
(S)-N-(5-((R)-1-(2,5-difluorophenyl)ethylamino)pyrazolo[1,5-a]pyrimidin-3-yShow More⌵

Mol. Formula:
C19H20F2N6OS

M.W.:
418.47

3 activity values

3 unique targets

Type:
Unknown

AlogP:
2.94

Polar Surface Area:
77.72

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA4778061

Name:
(R)-3-(5-(1-(2,5-difluorophenyl)ethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)-1Show More⌵

Mol. Formula:
C20H25F2N7O

M.W.:
417.46

3 activity values

3 unique targets

Type:
Unknown

AlogP:
3.21

Polar Surface Area:
77.80

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA4777109

Name:
(S)-N-(5-(((R)-1-(2,5-difluorophenyl)ethyl)(methyl)amino)pyrazolo[1,5-a]pyrShow More⌵

Mol. Formula:
C20H22F2N6OS

M.W.:
432.50

3 activity values

3 unique targets

Type:
Unknown

AlogP:
2.97

Polar Surface Area:
68.93

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA4763430

Name:
(S)-N-(5-(((R)-1-(2,5-difluorophenyl)ethyl)(methyl)amino)pyrazolo[1,5-a]pyrShow More⌵

Mol. Formula:
C20H22F2N6O2

M.W.:
416.43

3 activity values

3 unique targets

Type:
Unknown

AlogP:
2.80

Polar Surface Area:
86.00

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA4762176

Name:
N-(5-((R)-1-(2,5-difluorophenyl)ethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)-3Show More⌵

Mol. Formula:
C21H24F2N6O2

M.W.:
430.46

3 activity values

3 unique targets

Type:
Unknown

AlogP:
3.42

Polar Surface Area:
94.79

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4759162

Name:
(R)-3-(5-((1-(2,5-difluorophenyl)ethyl)(methyl)amino)pyrazolo[1,5-a]pyrimidShow More⌵

Mol. Formula:
C21H27F2N7O

M.W.:
431.49

3 activity values

3 unique targets

Type:
Unknown

AlogP:
3.23

Polar Surface Area:
69.01

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA4758658

Name:
(R)-N-(5-(1-(2,5-difluorophenyl)ethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)-3Show More⌵

Mol. Formula:
C18H18F2N6O2

M.W.:
388.38

3 activity values

3 unique targets

Type:
Unknown

AlogP:
2.39

Polar Surface Area:
94.79

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.64

DETAILS

ALA4756923

Name:
3-(5-((R)-1-(2,5-difluorophenyl)ethylamino)pyrazolo[1,5-a]pyrimidin-3-ylamiShow More⌵

Mol. Formula:
C22H20F2N6O3

M.W.:
454.44

3 activity values

3 unique targets

Type:
Unknown

AlogP:
2.09

Polar Surface Area:
111.86

HBA:
9

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA4754926

Name:
1-(5-((R)-1-(2,5-difluorophenyl)ethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)-3Show More⌵

Mol. Formula:
C19H22F2N6O2

M.W.:
404.42

3 activity values

3 unique targets

Type:
Unknown

AlogP:
3.07

Polar Surface Area:
103.58

HBA:
6

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4749323

Name:
(R)-N-(5-(1-(2,5-difluorophenyl)ethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)-4Show More⌵

Mol. Formula:
C20H23F2N7O

M.W.:
415.45

3 activity values

3 unique targets

Type:
Unknown

AlogP:
2.96

Polar Surface Area:
77.80

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA4745371

Name:
(R)-N-(5-((1-(2,5-difluorophenyl)ethyl)(methyl)amino)pyrazolo[1,5-a]pyrimidShow More⌵

Mol. Formula:
C19H20F2N6O2

M.W.:
402.41

3 activity values

3 unique targets

Type:
Unknown

AlogP:
2.41

Polar Surface Area:
86.00

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA4743163

Name:
(R)-3-(5-((1-(2,5-difluorophenyl)ethyl)(methyl)amino)pyrazolo[1,5-a]pyrimidShow More⌵

Mol. Formula:
C22H28F2N6O

M.W.:
430.50

3 activity values

3 unique targets

Type:
Unknown

AlogP:
4.86

Polar Surface Area:
65.77

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.61

DETAILS