Compounds

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MK-8245 analog
Name:
(5-{5-[4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}-2HShow More⌵
Mol. Formula:
C16H15BrFN7O3S
M.W.:
484.31
11 activity values
9 unique targets
Type:
Small molecule
AlogP:
2.23
Polar Surface Area:
119.15
HBA:
10
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.56
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ALA2153600
Name:
2-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)-5-(2H-tetrazol-5-yl)-1,3,4-thShow More⌵
Mol. Formula:
C14H13BrFN7OS
M.W.:
426.28
9 activity values
8 unique targets
Type:
Small molecule
AlogP:
2.67
Polar Surface Area:
92.71
HBA:
8
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.69
DETAILS
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ALA2153599
Name:
1-[5-(2H-Tetrazol-5-yl)-1,3,4-thiadiazol-2-yl]-4-[2-(trifluoromethyl)-phenoShow More⌵
Mol. Formula:
C15H14F3N7OS
M.W.:
397.39
10 activity values
8 unique targets
Type:
Small molecule
AlogP:
2.78
Polar Surface Area:
92.71
HBA:
8
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.72
DETAILS
CLOSE