Compounds

ALA4799226

Name:
(R)-4-(N-((6-cyclohexylpyridazin-3-yl)methyl)-1-(perfluorophenylsulfonyl)azShow More⌵

Mol. Formula:
C28H25F5N4O6S

M.W.:
640.59

1 activity values

1 unique targets

Type:
Unknown

AlogP:
4.62

Polar Surface Area:
141.00

HBA:
7

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA4796668

Name:
(R)-5-fluoro-2-hydroxy-4-(N-(4-isopropylbenzyl)-1-(perfluorophenylsulfonyl)Show More⌵

Mol. Formula:
C27H22F6N2O6S

M.W.:
616.54

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.04

Polar Surface Area:
115.22

HBA:
5

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA4795233

Name:
(R)-4-(N-((5-cyclohexylpyrazin-2-yl)methyl)-1-(perfluorophenylsulfonyl)azetShow More⌵

Mol. Formula:
C28H25F5N4O6S

M.W.:
640.59

1 activity values

1 unique targets

Type:
Unknown

AlogP:
4.62

Polar Surface Area:
141.00

HBA:
7

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA4794269

Name:
(R)-4-(N-(4-cyclohexylbenzyl)-1-(perfluorophenylsulfonyl)azetidine-2-carboxShow More⌵

Mol. Formula:
C30H27F5N2O5S

M.W.:
622.61

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.12

Polar Surface Area:
94.99

HBA:
4

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA4793287

Name:
(R)-2-hydroxy-4-(1-(perfluorophenylsulfonyl)-N-(4-(tetrahydro-2H-pyran-4-ylShow More⌵

Mol. Formula:
C29H25F5N2O7S

M.W.:
640.58

3 activity values

3 unique targets

Type:
Unknown

AlogP:
4.68

Polar Surface Area:
124.45

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA4793049

Name:
(R)-4-(N-((5-cyclopentylpyridin-2-yl)methyl)-1-(perfluorophenylsulfonyl)azeShow More⌵

Mol. Formula:
C28H24F5N3O6S

M.W.:
625.57

1 activity values

1 unique targets

Type:
Unknown

AlogP:
4.83

Polar Surface Area:
128.11

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA4792177

Name:
(R)-methyl 4-(N-((5-cyclohexylpyridin-2-yl)methyl)-1-(perfluorophenylsulfonShow More⌵

Mol. Formula:
C30H28F5N3O6S

M.W.:
653.63

2 activity values

2 unique targets

Type:
Unknown

AlogP:
5.31

Polar Surface Area:
117.11

HBA:
7

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA4788858

Name:
(R)-4-(N-((5-cyclopentylpyrazin-2-yl)methyl)-1-(perfluorophenylsulfonyl)azeShow More⌵

Mol. Formula:
C27H23F5N4O6S

M.W.:
626.56

1 activity values

1 unique targets

Type:
Unknown

AlogP:
4.23

Polar Surface Area:
141.00

HBA:
7

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA4787762

Name:
(R)-4-(N-((5-cyclopentylpyridin-2-yl)methyl)-1-(perfluorophenylsulfonyl)azeShow More⌵

Mol. Formula:
C28H23F6N3O5S

M.W.:
627.56

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.27

Polar Surface Area:
107.88

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA4786885

Name:
(R)-4-(N-((6-cyclohexylpyridin-3-yl)methyl)-1-(perfluorophenylsulfonyl)azetShow More⌵

Mol. Formula:
C29H26F5N3O6S

M.W.:
639.60

3 activity values

3 unique targets

Type:
Unknown

AlogP:
5.23

Polar Surface Area:
128.11

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.20

DETAILS

ALA4784885

Name:
(R)-4-(N-((5-cyclohexylpyridin-2-yl)methyl)-1-(perfluorophenylsulfonyl)azetShow More⌵

Mol. Formula:
C29H25F6N3O5S

M.W.:
641.59

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.66

Polar Surface Area:
107.88

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA4783679

Name:
(R)-4-(1-(perfluorophenylsulfonyl)-N-(4-(tetrahydro-2H-pyran-4-yl)benzyl)azShow More⌵

Mol. Formula:
C29H25F5N2O6S

M.W.:
624.58

1 activity values

1 unique targets

Type:
Unknown

AlogP:
4.97

Polar Surface Area:
104.22

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA4780608

Name:
(R)-5-(N-((5-cyclohexylpyridin-2-yl)methyl)-1-(perfluorophenylsulfonyl)azetShow More⌵

Mol. Formula:
C28H25F5N4O5S

M.W.:
624.59

1 activity values

1 unique targets

Type:
Unknown

AlogP:
4.91

Polar Surface Area:
120.77

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA4778873

Name:
(R)-4-(N-((5-cyclohexylpyridin-2-yl)methyl)-1-(perfluorophenylsulfonyl)azetShow More⌵

Mol. Formula:
C29H26F5N3O6S

M.W.:
639.60

4 activity values

4 unique targets

Type:
Unknown

AlogP:
5.23

Polar Surface Area:
128.11

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.20

DETAILS

ALA4777016

Name:
(R)-N-((5-cyclohexylpyridin-2-yl)methyl)-N-(1-oxo-1,3-dihydroisobenzofuran-Show More⌵

Mol. Formula:
C30H26F5N3O5S

M.W.:
635.61

27 activity values

8 unique targets

Type:
Unknown

AlogP:
5.49

Polar Surface Area:
96.88

HBA:
6

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA4764704

Name:
(R)-4-(N-((5-cyclohexylpyrazin-2-yl)methyl)-1-(perfluorophenylsulfonyl)azetShow More⌵

Mol. Formula:
C28H24F6N4O5S

M.W.:
642.58

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.05

Polar Surface Area:
120.77

HBA:
6

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA4763364

Name:
(R)-methyl 4-(N-((6-cyclohexylpyridin-3-yl)methyl)-1-(perfluorophenylsulfonShow More⌵

Mol. Formula:
C30H28F5N3O6S

M.W.:
653.63

2 activity values

2 unique targets

Type:
Unknown

AlogP:
5.31

Polar Surface Area:
117.11

HBA:
7

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA4761392

Name:
(R)-4-(N-(4-tert-butylbenzyl)-1-(perfluorophenylsulfonyl)azetidine-2-carboxShow More⌵

Mol. Formula:
C28H25F5N2O6S

M.W.:
612.57

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.08

Polar Surface Area:
115.22

HBA:
5

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA4761087

Name:
(R)-5-fluoro-2-hydroxy-4-(1-(perfluorophenylsulfonyl)-N-(4-(tetrahydro-2H-pShow More⌵

Mol. Formula:
C29H24F6N2O7S

M.W.:
658.57

1 activity values

1 unique targets

Type:
Unknown

AlogP:
4.82

Polar Surface Area:
124.45

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.20

DETAILS

ALA4760561

Name:
(R)-4-(N-(4-cyclohexylbenzyl)-1-(perfluorophenylsulfonyl)azetidine-2-carboxShow More⌵

Mol. Formula:
C30H26F6N2O5S

M.W.:
640.60

5 activity values

5 unique targets

Type:
Unknown

AlogP:
6.26

Polar Surface Area:
94.99

HBA:
4

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.18

DETAILS