Compounds

Type:
Unknown

AlogP:
5.36

Polar Surface Area:
65.54

HBA:
4

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4648312

Name:
N-methyl-N-(1-(2-(pyridin-2-ylamino)benzoyl)piperidin-4-yl)-2-trifluoromethShow More⌵

Mol. Formula:
C26H24F4N4O2

M.W.:
500.50

Type:
Unknown

AlogP:
5.36

Polar Surface Area:
65.54

HBA:
4

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4647112

Name:
N-methyl-N-(1-(2-([1,1'-biphenyl]-4-ylamino)benzoyl)piperidin-4-yl)-2-triflShow More⌵

Mol. Formula:
C33H29F4N3O2

M.W.:
575.61

Type:
Unknown

AlogP:
7.63

Polar Surface Area:
52.65

HBA:
3

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA4646912

Name:
N-methyl-N-(1-(2-((1-methyl-1H-pyrazol-5-yl)amino)benzoyl)piperidin-4-yl)-4Show More⌵

Mol. Formula:
C25H29N5O4S

M.W.:
495.61

Type:
Unknown

AlogP:
2.94

Polar Surface Area:
104.61

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA4646599

Name:
N-methyl-N-(1-(2-((1-methyl-1H-pyrazol-5-yl)amino)benzoyl)piperidin-4-yl)-4Show More⌵

Mol. Formula:
C26H29N5O3

M.W.:
459.55

Type:
Unknown

AlogP:
3.74

Polar Surface Area:
87.54

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA4645447

Name:
N-methyl-N-(1-(2-((4-methoxyphenyl)amino)benzoyl)piperidin-4-yl)-2-trifluorShow More⌵

Mol. Formula:
C28H27F4N3O3

M.W.:
529.53

Type:
Unknown

AlogP:
5.97

Polar Surface Area:
61.88

HBA:
4

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4644469

Name:
N-methyl-N-(1-(2-((1-methyl-1H-pyrazol-5-yl)amino)benzoyl)piperidin-4-yl)-4Show More⌵

Mol. Formula:
C25H26N6O2

M.W.:
442.52

Type:
Unknown

AlogP:
3.41

Polar Surface Area:
94.26

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA4644288

Name:
N-methyl-N-(1-(2-((1-methyl-1H-pyrazol-5-yl)amino)benzoyl)piperidin-4-yl)-2Show More⌵

Mol. Formula:
C25H25F4N5O2

M.W.:
503.50

Type:
Unknown

AlogP:
4.70

Polar Surface Area:
70.47

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA4642779

Name:
N-methyl-N-(1-(2-((4-carboxylphenyl)amino)benzoyl)piperidin-4-yl)-2-trifluoShow More⌵

Mol. Formula:
C28H25F4N3O4

M.W.:
543.52

Type:
Unknown

AlogP:
5.66

Polar Surface Area:
89.95

HBA:
4

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4642236

Name:
N-methyl-N-(1-(2-(pyridin-4-ylamino)benzoyl)piperidin-4-yl)-2-trifluoromethShow More⌵

Mol. Formula:
C26H24F4N4O2

M.W.:
500.50

Type:
Unknown

AlogP:
5.36

Polar Surface Area:
65.54

HBA:
4

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4641820

Name:
N-methyl-N-(1-(2-((1-methyl-1H-pyrazol-5-yl)amino)benzoyl)piperidin-4-yl)-4Show More⌵

Mol. Formula:
C24H26FN5O2

M.W.:
435.50

Type:
Unknown

AlogP:
3.68

Polar Surface Area:
70.47

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA4641704

Name:
N-methyl-N-(1-(2-((1-methyl-1H-pyrazol-5-yl)amino)benzoyl)piperidin-4-yl)-4Show More⌵

Mol. Formula:
C25H26F3N5O2

M.W.:
485.51

Type:
Unknown

AlogP:
4.56

Polar Surface Area:
70.47

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4639888

Name:
N-methyl-N-(1-(2-((1-methyl-1H-pyrazol-5-yl)amino)benzoyl)piperidin-4-yl)-4Show More⌵

Mol. Formula:
C24H26N6O4

M.W.:
462.51

Type:
Unknown

AlogP:
3.45

Polar Surface Area:
113.61

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA4639103

Name:
(4-(4-Fluoro-2-(trifluoromethyl)benzoyl)piperazin-1-yl)(2-(phenylamino)phenShow More⌵

Mol. Formula:
C25H21F4N3O2

M.W.:
471.45

Type:
Unknown

AlogP:
5.19

Polar Surface Area:
52.65

HBA:
3

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA4639086

Name:
[4-[4-fluoro-2-(trifluoromethyl)benzoyl]piperazin-1-yl]-[2-[(2-methylpyrazoShow More⌵

Mol. Formula:
C23H21F4N5O2

M.W.:
475.45

Type:
Unknown

AlogP:
3.92

Polar Surface Area:
70.47

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4635021

Name:
N-methyl-N-(1-(2-((2-methoxyphenyl)amino)benzoyl)piperidin-4-yl)-2-trifluorShow More⌵

Mol. Formula:
C28H27F4N3O3

M.W.:
529.53

Type:
Unknown

AlogP:
5.97

Polar Surface Area:
61.88

HBA:
4

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4633504

Name:
N-methyl-N-(1-(2-((2-cyanophenyl)amino)benzoyl)piperidin-4-yl)-2-trifluoromShow More⌵

Mol. Formula:
C28H24F4N4O2

M.W.:
524.52

Type:
Unknown

AlogP:
5.84

Polar Surface Area:
76.44

HBA:
4

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4632758

Name:
N-methyl-N-(1-(2-((4-cyano)phenylamino)benzoyl)piperidin-4-yl)-2-trifluoromShow More⌵

Mol. Formula:
C28H24F4N4O2

M.W.:
524.52

Type:
Unknown

AlogP:
5.84

Polar Surface Area:
76.44

HBA:
4

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4632598

Name:
N-methyl-N-(1-(2-(phenylamino)benzoyl)piperidin-4-yl)-2-trifluoromethyl-4-fShow More⌵

Mol. Formula:
C27H25F4N3O2

M.W.:
499.51