Compounds

Type:
---

AlogP:
6.05

Polar Surface Area:
130.24

HBA:
7

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.34

DETAILS

ALA5207578

Name:

Mol. Formula:
C25H24F2N4O4

M.W.:
482.49

42 activity values

7 unique targets

Type:
---

AlogP:
5.48

Polar Surface Area:
117.35

HBA:
6

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5175038

Name:

Mol. Formula:
C22H26F2N4O4

M.W.:
448.47

1 activity values

1 unique targets

Type:
---

AlogP:
4.42

Polar Surface Area:
117.35

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5174434

Name:
2-[3-[4-[[5-(3,4-difluoroanilino)-1,3,4-oxadiazole-2-carbonyl]amino]phenyl]Show More⌵

Mol. Formula:
C28H30F2N4O4

M.W.:
524.57

14 activity values

5 unique targets

Type:
---

AlogP:
6.65

Polar Surface Area:
117.35

HBA:
6

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.32

DETAILS

ALA4592655

Name:
trans-2-(4-(1-(5-(5,6-difluoro-1H-benzo[d]imidazol-2-yl)pyridin-2-yl)piperiShow More⌵

Mol. Formula:
C25H28F2N4O3

M.W.:
470.52

24 activity values

8 unique targets

Type:
Unknown

AlogP:
4.92

Polar Surface Area:
91.34

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA4592144

Name:
cis-2-(4-(5-(6-chloro-3H-imidazo[4,5-b]pyridin-2-yl)-2,3'-bipyridin-6'-yloxShow More⌵

Mol. Formula:
C24H22ClN5O3

M.W.:
463.93

Type:
Unknown

AlogP:
5.15

Polar Surface Area:
113.88

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA4585408

Name:
3-(5-(5-chloro-1H-benzo[d]imidazol-2-yl)-2,3'-bipyridin-6'-yloxy)-2,2-dimetShow More⌵

Mol. Formula:
C22H19ClN4O3

M.W.:
422.87

Type:
Unknown

AlogP:
4.83

Polar Surface Area:
100.99

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA4577468

Name:
4-((5-(5-chloro-1H-benzo[d]imidazol-2-yl)-2,3'-bipyridin-6'-ylamino)methyl)Show More⌵

Mol. Formula:
C25H18ClN5O2

M.W.:
455.91

7 activity values

7 unique targets

Type:
Unknown

AlogP:
5.65

Polar Surface Area:
103.79

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA4575608

Name:
4'-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)biphenyl-4-ol

Mol. Formula:
C20H13F3N2O

M.W.:
354.33

3 activity values

Type:
Unknown

AlogP:
5.62

Polar Surface Area:
48.91

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA4574644

Name:
4-(5-(4-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)phenyl)pyridin-2-yl)mShow More⌵

Mol. Formula:
C23H19F3N4O

M.W.:
424.43

3 activity values

Type:
Unknown

AlogP:
5.15

Polar Surface Area:
54.04

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA4572398

Name:
trans-2-(4-(1-(5-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)pyridin-2-ylShow More⌵

Mol. Formula:
C26H29F3N4O3

M.W.:
502.54

Type:
Unknown

AlogP:
5.66

Polar Surface Area:
91.34

HBA:
5

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4565611

Name:
trans-2-(4-(1-(5-(5-methyl-1H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-yl)piperShow More⌵

Mol. Formula:
C25H31N5O3

M.W.:
449.56

Type:
Unknown

AlogP:
4.35

Polar Surface Area:
104.23

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4563171

Name:
2-(4-(4-(5-((5-cyclobutyl-1,3,4-oxadiazol-2-yl)amino)pyridin-2-yl)phenyl)-2Show More⌵

Mol. Formula:
C26H28N4O4

M.W.:
460.53

5 activity values

Type:
Unknown

AlogP:
5.20

Polar Surface Area:
110.37

HBA:
7

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4562424

Name:
rac-2-(1-(5-(5-chloro-1H-benzo[d]imidazol-2-yl)-2,3'-bipyridin-6'-yl)-3,3-dShow More⌵

Mol. Formula:
C26H26ClN5O2

M.W.:
475.98

Type:
Unknown

AlogP:
5.67

Polar Surface Area:
95.00

HBA:
5

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4561313

Name:
cis-2-(4-(5-(5-cyano-1H-benzo[d]imidazol-2-yl)-2,3'-bipyridin-6'-yloxy)cyclShow More⌵

Mol. Formula:
C26H23N5O3

M.W.:
453.50

Type:
Unknown

AlogP:
4.97

Polar Surface Area:
124.78

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4557603

Name:
2-((1r,4r)-4-(4'-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)biphenyl-4-yShow More⌵

Mol. Formula:
C28H25F3N2O2

M.W.:
478.51

4 activity values

4 unique targets

Type:
Unknown

AlogP:
7.66

Polar Surface Area:
65.98

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA4555623

Name:
2-(4-(4-(5-(2-ethyl-4-methyloxazole-5-carboxamido)pyridin-2-yl)phenyl)-2-oxShow More⌵

Mol. Formula:
C27H29N3O5

M.W.:
475.55

3 activity values

Type:
Unknown

AlogP:
4.92

Polar Surface Area:
114.55

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4554202

Name:
rac-2-(5-(5-chloro-1H-benzo[d]imidazol-2-yl)-2,3'-bipyridin-6'-ylamino)cyclShow More⌵

Mol. Formula:
C24H22ClN5O2

M.W.:
447.93