Compounds

ALA5281885

Name:
6-(hydroxymethyl)-3-(4-(2-hydroxypropan-2-yl)phenyl)pyrrolo[1,2-a]pyrazin-1Show More⌵

Mol. Formula:
C17H18N2O3

M.W.:
298.34

Type:
---

AlogP:
2.01

Polar Surface Area:
77.73

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5281076

Name:
3-(4-(2-(2-hydroxyethoxy)propan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-Show More⌵

Mol. Formula:
C19H22N2O3

M.W.:
326.40

Type:
---

AlogP:
2.85

Polar Surface Area:
66.73

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5280682

Name:
(S)-3-(4-(2,4-dihydroxybutan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2Show More⌵

Mol. Formula:
C18H20N2O3

M.W.:
312.37

Type:
---

AlogP:
2.19

Polar Surface Area:
77.73

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5280345

Name:
3-(4-(2-hydroxypropan-2-yl)phenyl)-7-methylpyrrolo[1,2-a]pyrazin-1(2H)-one

Mol. Formula:
C17H18N2O2

M.W.:
282.34

Type:
---

AlogP:
2.83

Polar Surface Area:
57.50

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
Y

QED Weighted:
0.76

DETAILS

ALA5280167

Name:
7-chloro-3-(4-(2-hydroxypropan-2-yl)phenyl)pyrrolo[1,2-a]pyrazin-1(2H)-one

Mol. Formula:
C16H15ClN2O2

M.W.:
302.76

Type:
---

AlogP:
3.18

Polar Surface Area:
57.50

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5279709

Name:
2-(4-(2-hydroxypropan-2-yl)phenyl)-7-methylthieno[3,2-d]pyrimidin-4(3H)-one

Mol. Formula:
C16H16N2O2S

M.W.:
300.38

Type:
---

AlogP:
3.19

Polar Surface Area:
65.98

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5279214

Name:
3-(4-(2-hydroxypropan-2-yl)phenyl)pyrrolo[1,2-a]pyrazin-1(2H)-one

Mol. Formula:
C16H16N2O2

M.W.:
268.32

Type:
---

AlogP:
2.52

Polar Surface Area:
57.50

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
Y

QED Weighted:
0.75

DETAILS

ALA5278616

Name:
(S)-3-(4-(1,2-dihydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(Show More⌵

Mol. Formula:
C17H18N2O3

M.W.:
298.34

Type:
---

AlogP:
1.80

Polar Surface Area:
77.73

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5277753

Name:
4-(4-Oxo-3,4-dihydroquinazolin-2-yl)benzenesulfonamide

Mol. Formula:
C14H11N3O3S

M.W.:
301.33

Type:
---

AlogP:
1.24

Polar Surface Area:
105.91

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5277254

Name:
6-(4-(tert-butyl)phenyl)-3-methylimidazo[1,5-a]pyrazin-8(7H)-one

Mol. Formula:
C17H19N3O

M.W.:
281.36

Type:
---

AlogP:
3.30

Polar Surface Area:
50.16

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5276381

Name:
6-fluoro-3-(4-(2-hydroxypropan-2-yl)phenyl)pyrrolo[1,2-a]pyrazin-1(2H)-one

Mol. Formula:
C16H15FN2O2

M.W.:
286.31

Type:
---

AlogP:
2.66

Polar Surface Area:
57.50

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
Y

QED Weighted:
0.76

DETAILS

ALA5275705

Name:
5-Methyl-5-(4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl)imidazolidine-2,4-diShow More⌵

Mol. Formula:
C18H14N4O3

M.W.:
334.34

Type:
---

AlogP:
1.64

Polar Surface Area:
103.95

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA5275576

Name:
3-(4-(3-hydroxyoxetan-3-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one

Mol. Formula:
C17H16N2O3

M.W.:
296.33

Type:
---

AlogP:
1.82

Polar Surface Area:
66.73

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5275231

Name:
6-(4-(tert-butyl)phenyl)imidazo[1,5-a]pyrazin-8(7H)-one

Mol. Formula:
C16H17N3O

M.W.:
267.33

Type:
---

AlogP:
2.99

Polar Surface Area:
50.16

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
Y

QED Weighted:
0.74

DETAILS

ALA5274873

Name:
2-(4-(2-hydroxypropan-2-yl)phenyl)-7-methylpyrrolo[2,1-f][1,2,4]triazin-4(3Show More⌵

Mol. Formula:
C16H17N3O2

M.W.:
283.33

Type:
---

AlogP:
2.23

Polar Surface Area:
70.39

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5274180

Name:
6-(4-(tert-butyl)phenyl)imidazo[1,2-a]pyrazin-8(7H)-one

Mol. Formula:
C16H17N3O

M.W.:
267.33

Type:
---

AlogP:
2.99

Polar Surface Area:
50.16

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
Y

QED Weighted:
0.74

DETAILS

ALA5289848

Name:
6-(4-(2-hydroxypropan-2-yl)phenyl)-3-methylimidazo[1,5-a]pyrazin-8(7H)-one

Mol. Formula:
C16H17N3O2

M.W.:
283.33

Type:
---

AlogP:
2.23

Polar Surface Area:
70.39

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5284505

Name:
6-(4-(2-hydroxypropan-2-yl)phenyl)-2-methylpyrazolo[1,5-a]pyrazin-4(5H)-one

Mol. Formula:
C16H17N3O2

M.W.:
283.33

Type:
---

AlogP:
2.23

Polar Surface Area:
70.39

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5284314

Name:
6,7-difluoro-3-(4-(2-hydroxypropan-2-yl)phenyl)pyrrolo[1,2-a]pyrazin-1(2H)-Show More⌵

Mol. Formula:
C16H14F2N2O2

M.W.:
304.30

Type:
---

AlogP:
2.80

Polar Surface Area:
57.50

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5284305

Name:
2-(4-(2-hydroxypropan-2-yl)phenyl)-6-methylpyrazolo[5,1-f][1,2,4]triazin-4(Show More⌵

Mol. Formula:
C15H16N4O2

M.W.:
284.32

Type:
---

AlogP:
1.62

Polar Surface Area:
83.28

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.75

DETAILS