Compounds

ALA5272384

Name:
N-(4-(4-Methylpiperazin-1-yl)phenyl)-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C17H19N5S2

M.W.:
357.51

Type:
---

AlogP:
3.76

Polar Surface Area:
44.29

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5272094

Name:
N-(3-Fluorophenyl)-4-phenyl-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C18H12FN3S2

M.W.:
353.45

Type:
---

AlogP:
5.82

Polar Surface Area:
37.81

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5271848

Name:
N-(Naphthalen-1-yl)-(2,4'-bithiazol)-2-amine

Mol. Formula:
C16H11N3S2

M.W.:
309.42

Type:
---

AlogP:
5.16

Polar Surface Area:
37.81

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5270827

Name:
N-(4-(Piperazin-1-yl)phenyl)-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C16H17N5S2

M.W.:
343.48

Type:
---

AlogP:
3.42

Polar Surface Area:
53.08

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5270659

Name:
N-(3,5-Dimethoxyphenyl-4-(2-(prop-2-yn-1-yloxy)phenyl)-(2,4'-bithiazol)-2'-Show More⌵

Mol. Formula:
C23H19N3O3S2

M.W.:
449.56

Type:
---

AlogP:
5.71

Polar Surface Area:
65.50

HBA:
8

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.35

DETAILS

ALA5270417

Name:
N-(3,5-Dichlorophenyl)-5-methyl-4-phenyl-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C19H13Cl2N3S2

M.W.:
418.37

Type:
---

AlogP:
7.29

Polar Surface Area:
37.81

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA5270385

Name:
3-(2'-((3,5-Dimethoxyphenyl)amino)-(2,4'-bithiazol)-4-yl)benzonitrile

Mol. Formula:
C21H16N4O2S2

M.W.:
420.52

Type:
---

AlogP:
5.57

Polar Surface Area:
80.06

HBA:
8

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5270072

Name:
N-(3,5-Dichlorophenyl)-4,5-diphenyl-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C24H15Cl2N3S2

M.W.:
480.45

Type:
---

AlogP:
8.65

Polar Surface Area:
37.81

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA5269852

Name:
N-(3,4-Dimethoxyphenyl)-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C14H13N3O2S2

M.W.:
319.41

Type:
---

AlogP:
4.03

Polar Surface Area:
56.27

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5269615

Name:
N-(4-Methoxyphenyl)-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C13H11N3OS2

M.W.:
289.39

Type:
---

AlogP:
4.02

Polar Surface Area:
47.04

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5269203

Name:
4-(2-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C20H16ClN3O2S2

M.W.:
429.95

Type:
---

AlogP:
6.35

Polar Surface Area:
56.27

HBA:
7

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA5268929

Name:
4-(3-Methoxyphenyl)-N-(4-morpholinophenyl)-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C23H22N4O2S2

M.W.:
450.59

Type:
---

AlogP:
5.52

Polar Surface Area:
59.51

HBA:
8

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5268876

Name:
N-(3,5-Dimethoxyphenyl)-5-ethyl-4-phenyl-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C22H21N3O2S2

M.W.:
423.56

Type:
---

AlogP:
6.26

Polar Surface Area:
56.27

HBA:
7

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA5268442

Name:
N-(4-Morpholinophenyl)-4-phenyl-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C22H20N4OS2

M.W.:
420.56

Type:
---

AlogP:
5.51

Polar Surface Area:
50.28

HBA:
7

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5268347

Name:
N-(3-Methozyphenyl)-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C13H11N3OS2

M.W.:
289.39

Type:
---

AlogP:
4.02

Polar Surface Area:
47.04

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5268218

Name:
N-(3-Fluorophenyl)-5-isopropyl-4-phenyl-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C21H18FN3S2

M.W.:
395.53

Type:
---

AlogP:
6.94

Polar Surface Area:
37.81

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5268082

Name:
N-(2-Fluorophenyl)-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C12H8FN3S2

M.W.:
277.35

Type:
---

AlogP:
4.15

Polar Surface Area:
37.81

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5268036

Name:
N-(3,5-Dichlorophenyl)-4-(pyridin-4-yl)-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C17H10Cl2N4S2

M.W.:
405.33

Type:
---

AlogP:
6.38

Polar Surface Area:
50.70

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5267964

Name:
5-Ethyl-N-(3-fluorophenyl)-4-phenyl-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C20H16FN3S2

M.W.:
381.50

Type:
---

AlogP:
6.38

Polar Surface Area:
37.81

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5282286

Name:
N-(3,5-Dimethoxyphenyl)-4-(3-methoxyphenyl)-(2,4'-bithiazol)-2'-amine

Mol. Formula:
C21H19N3O3S2

M.W.:
425.54

Type:
---

AlogP:
5.70

Polar Surface Area:
65.50

HBA:
8

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.41

DETAILS