Compounds

Type:
Unknown

AlogP:
5.77

Polar Surface Area:
142.16

HBA:
6

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.16

DETAILS

ALA4567730

Name:
(7S,10R,11S)-7-((1H-indol-3-yl)methyl)-11-methyl-10-(1-tosyl-1H-pyrrol-2-ylShow More⌵

Mol. Formula:
C40H39F3N4O7S

M.W.:
776.83

Type:
Unknown

AlogP:
6.40

Polar Surface Area:
148.59

HBA:
8

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.13

DETAILS

ALA4566116

Name:
(7S,10R,11S)-7-((1H-indol-3-yl)methyl)-11-methyl-4-phenoxy-10-(1-tosyl-1H-pShow More⌵

Mol. Formula:
C39H40N4O7S

M.W.:
708.84

Type:
Unknown

AlogP:
5.38

Polar Surface Area:
148.59

HBA:
8

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA4554677

Name:
(3S,7S,13S,14R,E)-3-((1H-Indol-3-yl)methyl)-13-methyl-14-(1-tosyl-1H-pyrrolShow More⌵

Mol. Formula:
C39H38F3N5O5S

M.W.:
745.82

Type:
Unknown

AlogP:
6.26

Polar Surface Area:
142.16

HBA:
6

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA4552083

Name:
(7S,10R,11S,E)-7-((1H-Indol-3-yl)methyl)-11-methyl-10-(1-tosyl-1H-pyrrol-2-Show More⌵

Mol. Formula:
C33H36N4O6S

M.W.:
616.74

Type:
Unknown

AlogP:
4.32

Polar Surface Area:
139.36

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA4549101

Name:
(8S,11R,12S,E)-8-((1H-Indol-3-yl)methyl)-12-methyl-11-(1-tosyl-1H-pyrrol-2-Show More⌵

Mol. Formula:
C34H38N4O6S

M.W.:
630.77

Type:
Unknown

AlogP:
4.71

Polar Surface Area:
139.36

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA4546113

Name:
(7S,10R,11S,E)-7-((1H-Indol-3-yl)methyl)-11-methyl-10-phenyl-1-oxa-6,9-diazShow More⌵

Mol. Formula:
C28H31N3O4

M.W.:
473.57

Type:
Unknown

AlogP:
3.97

Polar Surface Area:
100.29

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4544773

Name:
(8S,11R,12S,E)-8-((1H-Indol-3-yl)methyl)-12-methyl-11-phenyl-1-oxa-7,10-diaShow More⌵

Mol. Formula:
C29H33N3O4

M.W.:
487.60

Type:
Unknown

AlogP:
4.36

Polar Surface Area:
100.29

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA4539845

Name:
(3S,7S,13S,14R,E)-3-((1H-Indol-3-yl)methyl)-7-(4-chlorophenyl)-13-methyl-14Show More⌵

Mol. Formula:
C38H38ClN5O5S

M.W.:
712.27

Type:
Unknown

AlogP:
5.90

Polar Surface Area:
142.16

HBA:
6

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.16

DETAILS

ALA4533818

Name:
(3S,7S,13S,14R,E)-3-((1H-Indol-3-yl)methyl)-7-(4-fluorophenyl)-13-methyl-14Show More⌵

Mol. Formula:
C33H33FN4O3

M.W.:
552.65

Type:
Unknown

AlogP:
5.04

Polar Surface Area:
103.09

HBA:
3

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA4517868

Name:
(7S,10R,11S)-7-((1H-indol-3-yl)methyl)-11-methyl-4-phenyl-10-(1-tosyl-1H-pyShow More⌵

Mol. Formula:
C39H40N4O6S

M.W.:
692.84

Type:
Unknown

AlogP:
5.71

Polar Surface Area:
139.36

HBA:
7

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA4514209

Name:
(3S,7S,13S,14R,E)-3-((1H-Indol-3-yl)methyl)-13-methyl-14-phenyl-7-(4-(triflShow More⌵

Mol. Formula:
C34H33F3N4O3

M.W.:
602.66

Type:
Unknown

AlogP:
5.92

Polar Surface Area:
103.09

HBA:
3

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA4475832

Name:
(3S,7S,13S,14R,E)-3-((1H-Indol-3-yl)methyl)-7-(4-chlorophenyl)-13-methyl-14Show More⌵

Mol. Formula:
C33H33ClN4O3

M.W.:
569.11

Type:
Unknown

AlogP:
5.55

Polar Surface Area:
103.09

HBA:
3

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA4473699

Name:
(3S,15S,16R,E)-3-((1H-Indol-3-yl)methyl)-15-methyl-16-(1-tosyl-1H-pyrrol-2-Show More⌵

Mol. Formula:
C34H39N5O5S

M.W.:
629.78

Type:
Unknown

AlogP:
4.28

Polar Surface Area:
142.16

HBA:
6

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA4473257

Name:
(3S,7S,13S,14R,E)-3-((1H-Indol-3-yl)methyl)-13-methyl-14-(1-tosyl-1H-pyrrolShow More⌵

Mol. Formula:
C39H38F3N5O5S

M.W.:
745.82

Type:
Unknown

AlogP:
6.26

Polar Surface Area:
142.16

HBA:
6

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA4465479

Name:
(3S,7S,13S,14R,E)-3-((1H-Indol-3-yl)methyl)-13-methyl-7-(p-tolyl)-14-(1-tosShow More⌵

Mol. Formula:
C39H41N5O5S

M.W.:
691.85

Type:
Unknown

AlogP:
5.55

Polar Surface Area:
142.16

HBA:
6

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.17

DETAILS

ALA4465198

Name:
(3S,7S,13S,14R,E)-3-((1H-Indol-3-yl)methyl)-13-methyl-7-phenethyl-14-(1-tosShow More⌵

Mol. Formula:
C40H43N5O5S

M.W.:
705.88

Type:
Unknown

AlogP:
5.50

Polar Surface Area:
142.16

HBA:
6

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.16

DETAILS

ALA4460339

Name:
(3S,7R,13S,14R,E)-3-((1H-Indol-3-yl)methyl)-13-methyl-7-phenethyl-14-(1-tosShow More⌵

Mol. Formula:
C40H43N5O5S

M.W.:
705.88

Type:
Unknown

AlogP:
5.50

Polar Surface Area:
142.16

HBA:
6

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.16

DETAILS

ALA4458126

Name:
(7S,10R,11S)-7-((1H-indol-3-yl)methyl)-4-(benzo[d][1,3]dioxol-5-yloxy)-11-mShow More⌵

Mol. Formula:
C35H35N3O7

M.W.:
609.68

Type:
Unknown

AlogP:
4.76

Polar Surface Area:
127.98

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA4457207

Name:
(3S,14S,15R,E)-3-((1H-Indol-3-yl)methyl)-14-methyl-15-(1-tosyl-1H-pyrrol-2-Show More⌵

Mol. Formula:
C33H37N5O5S

M.W.:
615.76