Compounds

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2‐Methyl‐11‐(1‐methylethyl)‐8‐(pyrimidin‐2‐yloxy)‐2,5,6,11,12,13‐hexahydro‐4H‐indazolo[5,4‐a]pyrrolo[3,4‐c]carbazol‐4‐one
Name:
9-isopropyl-5-methyl-12-(pyrimidin-2-yloxy)-5,7,8,9-tetrahydro-1H-indazolo[Show More⌵
Mol. Formula:
C27H24N6O2
M.W.:
464.53
1 activity values
1 unique targets
Type:
Small molecule
AlogP:
4.70
Polar Surface Area:
86.86
HBA:
7
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.42
DETAILS
CLOSE
ALA3355006
Name:
7-(1-isopropyl-5-((1R,5S,6r)-3-(oxetan-3-yl)-3-azabicyclo[3.1.0]hexan-6-yl)Show More⌵
Mol. Formula:
C20H25N7O
M.W.:
379.47
2 activity values
2 unique targets
Type:
Small molecule
AlogP:
2.03
Polar Surface Area:
97.88
HBA:
7
HBD:
2
#RO5 Violations:
---
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.72
DETAILS
CLOSE
ALA3355005
Name:
5-(1-isopropyl-5-((1R,5S,6r)-3-(oxetan-3-yl)-3-azabicyclo[3.1.0]hexan-6-yl)Show More⌵
Mol. Formula:
C22H24F3N5O
M.W.:
431.46
2 activity values
2 unique targets
Type:
Small molecule
AlogP:
4.07
Polar Surface Area:
58.97
HBA:
5
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.68
DETAILS
CLOSE
ALA3355004
Name:
3-fluoro-5-(1-isopropyl-5-(1-(oxetan-3-yl)pyrrolidin-3-yl)-1H-pyrazol-3-yl)Show More⌵
Mol. Formula:
C20H24FN5O
M.W.:
369.44
2 activity values
2 unique targets
Type:
Small molecule
AlogP:
3.33
Polar Surface Area:
58.97
HBA:
5
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.77
DETAILS
CLOSE
ALA3355003
Name:
5-(1-isopropyl-5-(1-methylpiperidin-4-yl)-1H-pyrazol-3-yl)-3-(trifluoromethShow More⌵
Mol. Formula:
C20H24F3N5
M.W.:
391.44
2 activity values
2 unique targets
Type:
Small molecule
AlogP:
4.84
Polar Surface Area:
49.74
HBA:
4
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.70
DETAILS
CLOSE