Compounds

Type:
---

AlogP:
4.73

Polar Surface Area:
51.66

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5194870

Name:
2-(2-(4-chlorophenyl)-3-(2-(dipropylamino)-2-oxoethyl)imidazo[1,2-a]pyridinShow More⌵

Mol. Formula:
C23H27ClN4O3

M.W.:
442.95

Type:
---

AlogP:
4.34

Polar Surface Area:
86.94

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA5187502

Name:
4-(2-chlorophenyl)-N-methyl-N-(p-tolylmethyl)quinazoline-2-carboxamide

Mol. Formula:
C24H20ClN3O

M.W.:
401.90

Type:
---

AlogP:
5.53

Polar Surface Area:
46.09

HBA:
3

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5179737

Name:
N-methyl-N-(2-phenoxyphenyl)acetamide

Mol. Formula:
C15H15NO2

M.W.:
241.29

Type:
---

AlogP:
3.46

Polar Surface Area:
29.54

HBA:
2

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5179024

Name:
ethyl (2R)-2-[[(2S)-2-[[2-(5-isothiocyanato-2-phenyl-1H-indol-3-yl)-2-oxo-aShow More⌵

Mol. Formula:
C34H34N4O5S

M.W.:
610.74

Type:
---

AlogP:
5.57

Polar Surface Area:
129.72

HBA:
7

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
13

Passes Ro3:
N

QED Weighted:
0.06

DETAILS

ALA5174807

Name:
2-(4-(6,8-dichloro-3-(2-(dipropylamino)-2-oxoethyl)imidazo[1,2-a]pyridin-2-Show More⌵

Mol. Formula:
C23H25Cl2N3O4

M.W.:
478.38

Type:
---

AlogP:
4.96

Polar Surface Area:
84.14

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5172740

Name:
ethyl (2R)-2-[[(2S)-4-methyl-2-[[2-oxo-2-(2-phenyl-1H-indol-3-yl)acetyl]amiShow More⌵

Mol. Formula:
C33H35N3O5

M.W.:
553.66

Type:
---

AlogP:
4.84

Polar Surface Area:
117.36

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.13

DETAILS

ALA5169788

Name:
(2R)-2-[[(2S)-4-methyl-2-[[2-oxo-2-(2-phenyl-1H-indol-3-yl)acetyl]amino]penShow More⌵

Mol. Formula:
C31H31N3O5

M.W.:
525.61

Type:
---

AlogP:
4.36

Polar Surface Area:
128.36

HBA:
4

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.17

DETAILS

ALA4799027

Name:
2-((3,5-Dimethylphenyl)(4-(2-fluoroethoxy)benzyl)amino)-N,N-diethylacetamidShow More⌵

Mol. Formula:
C23H31FN2O2

M.W.:
386.51

Type:
Unknown

AlogP:
4.53

Polar Surface Area:
32.78

HBA:
3

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA4798757

Name:
1-((6-Methoxypyridin-3-yl)methyl)-N,5-dimethyl-N-(prop-2-yn-1-yl)-1H-indoleShow More⌵

Mol. Formula:
C21H21N3O2

M.W.:
347.42

Type:
Unknown

AlogP:
3.11

Polar Surface Area:
47.36

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA4793373

Name:
N,N-diethyl-2-(11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-5-yl)acetaShow More⌵

Mol. Formula:
C19H21N3O2

M.W.:
323.40

Type:
Unknown

AlogP:
3.26

Polar Surface Area:
52.65

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.94

DETAILS

ALA4792527

Name:
N,N-dimethyl-2-(1-methyl-4,10-dihydrobenzo[b]pyrazolo[3,4-e][1,4]diazepin-5Show More⌵

Mol. Formula:
C15H19N5O

M.W.:
285.35

Type:
Unknown

AlogP:
1.57

Polar Surface Area:
53.40

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA4791086

Name:
N,N-Diethyl-1-(4-hydroxybenzyl)-5-methyl-1H-indole-2-carboxamide

Mol. Formula:
C21H24N2O2

M.W.:
336.44

Type:
Unknown

AlogP:
4.19

Polar Surface Area:
45.47

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA4790427

Name:
5-Acetamido-1-(4-methoxybenzyl)-N-methyl-N-(prop-2-yn-1-yl)-1H-indole-2-carShow More⌵

Mol. Formula:
C23H23N3O3

M.W.:
389.46

Type:
Unknown

AlogP:
3.36

Polar Surface Area:
63.57

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA4789235

Name:
N-benzyl-N-ethyl-2-(2-(4-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidiShow More⌵

Mol. Formula:
C26H28N4O2

M.W.:
428.54

Type:
Unknown

AlogP:
4.61

Polar Surface Area:
59.73

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4785758

Name:
2-((3,5-Dimethylphenyl)(4-isopropoxybenzyl)amino)-N,N-diethylacetamide

Mol. Formula:
C24H34N2O2

M.W.:
382.55

Type:
Unknown

AlogP:
4.97

Polar Surface Area:
32.78

HBA:
3

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA4785399

Name:
N,N-Diethyl-1-((6-methoxypyridin-3-yl)methyl)-1H-benzo[d]imidazole-2-carboxShow More⌵

Mol. Formula:
C19H22N4O2

M.W.:
338.41

Type:
Unknown

AlogP:
2.97

Polar Surface Area:
60.25

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA4780024

Name:
N-Benzyl-1-(4-chlorobenzyl)-N-methyl-1H-benzo[d]imidazole-2-carboxamide

Mol. Formula:
C23H20ClN3O

M.W.:
389.89