Compounds

ALA5208240

Name:
N-cyclohexyl-7-(4-cyclopentylpiperazin-1-yl)-2-(2,4-dimethoxyphenyl)imidazoShow More⌵

Mol. Formula:
C30H41N5O2

M.W.:
503.69

3 activity values

3 unique targets

Type:
---

AlogP:
5.83

Polar Surface Area:
54.27

HBA:
7

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5205931

Name:
2-(2-(benzyloxy)-4-methoxyphenyl)-7-(4-cyclopentylpiperazin-1-yl)-3-(pyrrolShow More⌵

Mol. Formula:
C35H43N5O2

M.W.:
565.76

2 activity values

2 unique targets

Type:
---

AlogP:
6.25

Polar Surface Area:
45.48

HBA:
7

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5205089

Name:
7-bromo-2-phenylimidazo[1,2-a]pyridine

Mol. Formula:
C13H9BrN2

M.W.:
273.13

2 activity values

2 unique targets

Type:
---

AlogP:
3.76

Polar Surface Area:
17.30

HBA:
2

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA5204617

Name:
7-(4-cyclopentylpiperazin-1-yl)-2-(4-methoxyphenyl)imidazo[1,2-a]pyridine

Mol. Formula:
C23H28N4O

M.W.:
376.50

2 activity values

2 unique targets

Type:
---

AlogP:
4.07

Polar Surface Area:
33.01

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5200947

Name:
2-(4-methoxyphenyl)-7-(piperazin-1-yl)imidazo[1,2-a]pyridine

Mol. Formula:
C18H20N4O

M.W.:
308.39

2 activity values

2 unique targets

Type:
---

AlogP:
2.42

Polar Surface Area:
41.80

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5200138

Name:
7-(4-cyclopentylpiperazin-1-yl)-2-(2,4-dimethoxyphenyl)-3-(pyrrolidin-1-ylmShow More⌵

Mol. Formula:
C29H39N5O2

M.W.:
489.66

13 activity values

7 unique targets

Type:
---

AlogP:
4.68

Polar Surface Area:
45.48

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5197857

Name:
4-(3-(5-methoxy-2-(7-(piperazin-1-yl)imidazo[1,2-a]pyridin-2-yl)phenoxy)proShow More⌵

Mol. Formula:
C25H33N5O3

M.W.:
451.57

2 activity values

2 unique targets

Type:
---

AlogP:
2.52

Polar Surface Area:
63.50

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5195571

Name:
4-((2-(2,4-dimethoxyphenyl)-7-(4-isopropylpiperazin-1-yl)imidazo[1,2-a]pyriShow More⌵

Mol. Formula:
C27H37N5O3

M.W.:
479.63

2 activity values

2 unique targets

Type:
---

AlogP:
3.38

Polar Surface Area:
54.71

HBA:
8

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5194647

Name:
2-(2,4-dimethoxyphenyl)-N-(2-morpholinoethyl)imidazo[1,2-a]pyridin-7-amine

Mol. Formula:
C21H26N4O3

M.W.:
382.46

2 activity values

2 unique targets

Type:
---

AlogP:
2.76

Polar Surface Area:
60.26

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA5193639

Name:
2-(2,4-dimethoxyphenyl)-N-(3-(pyrrolidin-1-yl)propyl)imidazo[1,2-a]pyridin-Show More⌵

Mol. Formula:
C22H28N4O2

M.W.:
380.49

11 activity values

7 unique targets

Type:
---

AlogP:
3.92

Polar Surface Area:
51.03

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5193165

Name:
2-(2,4-dimethoxyphenyl)-7-(piperazin-1-yl)imidazo[1,2-a]pyridine

Mol. Formula:
C19H22N4O2

M.W.:
338.41

4 activity values

4 unique targets

Type:
---

AlogP:
2.43

Polar Surface Area:
51.03

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5191419

Name:
tert-butyl 4-(2-(4-methoxy-2-(3-(pyrrolidin-1-yl)propoxy)phenyl)imidazo[1,2Show More⌵

Mol. Formula:
C30H41N5O4

M.W.:
535.69

2 activity values

2 unique targets

Type:
---

AlogP:
4.93

Polar Surface Area:
71.78

HBA:
8

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA5189243

Name:
2-(4-methoxy-2-(3-(pyrrolidin-1-yl)propoxy)phenyl)-7-(piperazin-1-yl)imidazShow More⌵

Mol. Formula:
C25H33N5O2

M.W.:
435.57

3 activity values

3 unique targets

Type:
---

AlogP:
3.28

Polar Surface Area:
54.27

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA5188687

Name:
(4-(2-(2-(benzyloxy)-4-methoxyphenyl)imidazo[1,2-a]pyridin-7-yl)piperazin-1Show More⌵

Mol. Formula:
C32H29FN4O3

M.W.:
536.61

2 activity values

2 unique targets

Type:
---

AlogP:
5.69

Polar Surface Area:
59.31

HBA:
6

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA5187807

Name:
4-(3-(2-(7-(4-cyclopentylpiperazin-1-yl)imidazo[1,2-a]pyridin-2-yl)-5-methoShow More⌵

Mol. Formula:
C30H41N5O3

M.W.:
519.69

10 activity values

6 unique targets

Type:
---

AlogP:
4.18

Polar Surface Area:
54.71

HBA:
8

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA5187075

Name:
(4-(2-(2-(benzyloxy)-4-methoxyphenyl)imidazo[1,2-a]pyridin-7-yl)piperazin-1Show More⌵

Mol. Formula:
C32H30N4O3

M.W.:
518.62

2 activity values

2 unique targets

Type:
---

AlogP:
5.55

Polar Surface Area:
59.31

HBA:
6

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA5186733

Name:
2-(2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-amine

Mol. Formula:
C15H15N3O2

M.W.:
269.30

2 activity values

2 unique targets

Type:
---

AlogP:
2.60

Polar Surface Area:
61.78

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5186660

Name:
cyclopentyl(4-(2-(2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl)piperazin-Show More⌵

Mol. Formula:
C25H30N4O3

M.W.:
434.54

2 activity values

2 unique targets

Type:
---

AlogP:
3.86

Polar Surface Area:
59.31

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5186293

Name:
2-(7-(4-cyclopentylpiperazin-1-yl)-3-(pyrrolidin-1-ylmethyl)imidazo[1,2-a]pShow More⌵

Mol. Formula:
C28H37N5O2

M.W.:
475.64

2 activity values

2 unique targets

Type:
---

AlogP:
4.38

Polar Surface Area:
56.48

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5186157

Name:
2-(4-methoxyphenyl)imidazo[1,2-a]pyridin-3-amine

Mol. Formula:
C14H13N3O

M.W.:
239.28

2 activity values

2 unique targets

Type:
---

AlogP:
2.59

Polar Surface Area:
52.55

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.75

DETAILS