Compounds

Type:
Protein

AlogP:
-1.82

Polar Surface Area:
183.04

HBA:
7

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA237413

Name:
MePhe-Ala-Ala-Gly-Gly-MePhe-NH2

Mol. Formula:
C30H41N7O6

M.W.:
595.70

2 activity values

2 unique targets

Type:
Protein

AlogP:
-1.39

Polar Surface Area:
191.83

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.14

DETAILS

ALA237224

Name:
MePhe-Ala-Ala-Ala-Ala-MePhe-NH2

Mol. Formula:
C32H45N7O6

M.W.:
623.76

Type:
Protein

AlogP:
-0.61

Polar Surface Area:
191.83

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.14

DETAILS

ALA237220

Name:
Phe(C2)-Ala-Ala-Ala-Ala-Phe(N2)-NH2 (precyclic)

Mol. Formula:
C35H50N8O8

M.W.:
710.83

2 activity values

2 unique targets

Type:
Small molecule

AlogP:
-1.44

Polar Surface Area:
255.15

HBA:
9

HBD:
8

#RO5 Violations:
2

#Rotatable Bonds:
21

Passes Ro3:
N

QED Weighted:
0.07

DETAILS

ALA236147

Name:
c(Phe(C2)-MeGly-MeGly-MeGly-MeGly-Phe(N2)-NH2)

Mol. Formula:
C35H48N8O7

M.W.:
692.82

Type:
Small molecule

AlogP:
-1.53

Polar Surface Area:
185.77

HBA:
8

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.33

DETAILS

ALA429263

Name:
c(Phe(C2)-MeGly-MeGly-MeGly-Gly-Phe(N2)-NH2)

Mol. Formula:
C34H46N8O7

M.W.:
678.79

Type:
Small molecule

AlogP:
-1.88

Polar Surface Area:
194.56

HBA:
8

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA391995

Name:
c(Phe(C2)-MeGly-MeGly-Gly-Gly-Phe(N2)-NH2)

Mol. Formula:
C33H44N8O7

M.W.:
664.76

Type:
Small molecule

AlogP:
-2.22

Polar Surface Area:
203.35

HBA:
8

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA391994

Name:
c(Phe(C2)-MeGly-Gly-Gly-Gly-Phe(N2)-NH2)

Mol. Formula:
C32H42N8O7

M.W.:
650.74

7 activity values

Type:
Small molecule

AlogP:
-2.56

Polar Surface Area:
212.14

HBA:
8

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.20

DETAILS

ALA391932

Name:
c(Phe(C2)-Ala-Ala-Ala-Ala-Phe(N2)-NH2)

Mol. Formula:
C35H48N8O7

M.W.:
692.82

5 activity values

Type:
Small molecule

AlogP:
-1.35

Polar Surface Area:
220.93

HBA:
8

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA428723

Name:
c(Phe(C2)-Ala-Ala-Ala-Gly-Phe(N2)-NH2)

Mol. Formula:
C34H46N8O7

M.W.:
678.79

Type:
Small molecule

AlogP:
-1.74

Polar Surface Area:
220.93

HBA:
8

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA391993

Name:
c(Phe(C2)-Ala-Ala-Gly-Gly-Phe(N2)-NH2)

Mol. Formula:
C33H44N8O7

M.W.:
664.76

Type:
Small molecule

AlogP:
-2.13

Polar Surface Area:
220.93

HBA:
8

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.18

DETAILS

ALA391992

Name:
c(Phe(C2)-Ala-Gly-Gly-Gly-Phe(N2)-NH2)

Mol. Formula:
C32H42N8O7

M.W.:
650.74

Type:
Small molecule

AlogP:
-2.51

Polar Surface Area:
220.93

HBA:
8

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.18

DETAILS

ALA391991

Name:
c(DPhe(C5)-Gly-Gly-Gly-Gly-Phe(N2)-NH2)

Mol. Formula:
C34H48N8O6

M.W.:
664.81

Type:
Small molecule

AlogP:
-1.26

Polar Surface Area:
203.86

HBA:
8

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.20

DETAILS

ALA235919

Name:
c(Phe(C4)-Gly-Gly-Gly-Gly-Phe(N2)-NH2)

Mol. Formula:
C33H44N8O7

M.W.:
664.76

Type:
Small molecule

AlogP:
-2.12

Polar Surface Area:
220.93

HBA:
8

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.18

DETAILS

ALA235515

Name:
c(Phe(C3)-Gly-Gly-Gly-Gly-Phe(N2) NH2

Mol. Formula:
C32H42N8O7

M.W.:
650.74