Compounds

Type:
Unknown

AlogP:
5.41

Polar Surface Area:
78.52

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4876138

Name:
N4-(5-ethyl-1H-pyrazol-3-yl)-5-fluoro-N2-(4-fluorophenethyl)quinazoline-2,4Show More⌵

Mol. Formula:
C21H20F2N6

M.W.:
394.43

Type:
Unknown

AlogP:
4.59

Polar Surface Area:
78.52

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4876072

Name:
N4-(5-ethyl-1H-pyrazol-3-yl)-5-fluoro-N2-phenethylquinazoline-2,4-diamine

Mol. Formula:
C21H21FN6

M.W.:
376.44

Type:
Unknown

AlogP:
4.45

Polar Surface Area:
78.52

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA4875929

Name:
(S)-N4-(3-Ethyl-1H-pyrazol-5-yl)-N2-(1-(5-fluoropyridin-2-yl)-ethyl)-5-methShow More⌵

Mol. Formula:
C21H22FN7

M.W.:
391.45

7 activity values

4 unique targets

Type:
Unknown

AlogP:
4.67

Polar Surface Area:
91.41

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA4875743

Name:
(S)-N4-(5-ethyl-1H-pyrazol-3-yl)-5-fluoro-N2-(1-(5-fluoropyrimidin-2-yl)ethShow More⌵

Mol. Formula:
C19H18F2N8

M.W.:
396.40

Type:
Unknown

AlogP:
3.90

Polar Surface Area:
104.30

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4875677

Name:
N4-(5-ethyl-1H-pyrazol-3-yl)-N2-(4-fluorophenethyl)-6-methoxyquinazoline-2,Show More⌵

Mol. Formula:
C22H23FN6O

M.W.:
406.47

Type:
Unknown

AlogP:
4.46

Polar Surface Area:
87.75

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4875533

Name:
4-(2-(1H-pyrazol-3-yl)hydrazinyl)-5-fluoro-N-phenethylquinazolin-2-amine

Mol. Formula:
C19H17FN6

M.W.:
348.39

Type:
Unknown

AlogP:
3.89

Polar Surface Area:
78.52

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA4874424

Name:
N2-(4-chlorobenzyl)-N4-(5-ethyl-1H-pyrazol-3-yl)-5-methoxyquinazoline-2,4-dShow More⌵

Mol. Formula:
C21H21ClN6O

M.W.:
408.89

4 activity values

3 unique targets

Type:
Unknown

AlogP:
4.93

Polar Surface Area:
87.75

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4872426

Name:
N2-(4-chlorobenzyl)-N4-(5-ethyl-1H-pyrazol-3-yl)-5-methylquinazoline-2,4-diShow More⌵

Mol. Formula:
C21H21ClN6

M.W.:
392.89

3 activity values

3 unique targets

Type:
Unknown

AlogP:
5.23

Polar Surface Area:
78.52

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4871944

Name:
(S)-N4-(5-ethyl-1H-pyrazol-3-yl)-5-fluoro-N2-(1-p-tolylethyl)quinazoline-2,Show More⌵

Mol. Formula:
C22H23FN6

M.W.:
390.47

Type:
Unknown

AlogP:
5.28

Polar Surface Area:
78.52

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4870615

Name:
(S)-N4-(5-ethyl-1H-pyrazol-3-yl)-5-fluoro-N2-(1-(5-fluoropyridin-2-yl)ethylShow More⌵

Mol. Formula:
C20H19F2N7

M.W.:
395.42

Type:
Unknown

AlogP:
4.51

Polar Surface Area:
91.41

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4869975

Name:
N4-(5-ethyl-1H-pyrazol-3-yl)-N2-(3-fluorobenzyl)quinazoline-2,4-diamine

Mol. Formula:
C21H21FN6

M.W.:
376.44

Type:
Unknown

AlogP:
4.97

Polar Surface Area:
78.52

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA4869307

Name:
7-chloro-N4-(5-ethyl-1H-pyrazol-3-yl)-N2-(4-fluorophenethyl)quinazoline-2,4Show More⌵

Mol. Formula:
C21H20ClFN6

M.W.:
410.88

Type:
Unknown

AlogP:
5.11

Polar Surface Area:
78.52

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4868574

Name:
N4-(5-ethyl-1H-pyrazol-3-yl)-5-fluoro-N2-(2-morpholinoethyl)quinazoline-2,4Show More⌵

Mol. Formula:
C19H24FN7O

M.W.:
385.45

Type:
Unknown

AlogP:
2.54

Polar Surface Area:
90.99

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4865763

Name:
(R)-N4-(5-ethyl-1H-pyrazol-3-yl)-N2-(1-(4-fluorophenyl)ethyl)quinazoline-2,Show More⌵

Mol. Formula:
C21H21FN6

M.W.:
376.44

Type:
Unknown

AlogP:
4.97

Polar Surface Area:
78.52

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA4865487

Name:
(S)-7-chloro-N4-(5-ethyl-1H-pyrazol-3-yl)-N2-(1-(4-fluorophenyl)ethyl)quinaShow More⌵

Mol. Formula:
C21H20ClFN6

M.W.:
410.88

Type:
Unknown

AlogP:
5.62

Polar Surface Area:
78.52

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA4865412

Name:
(S)-N4-(5-ethyl-1H-pyrazol-3-yl)-N2-(1-(4-methoxyphenyl)ethyl)quinazoline-2Show More⌵

Mol. Formula:
C22H24N6O

M.W.:
388.48

Type:
Unknown

AlogP:
4.84

Polar Surface Area:
87.75

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4860927

Name:
(S)-N4-(5-ethyl-1H-pyrazol-3-yl)-7-fluoro-N2-(1-(4-fluorophenyl)ethyl)quinaShow More⌵

Mol. Formula:
C21H20F2N6

M.W.:
394.43

Type:
Unknown

AlogP:
5.11

Polar Surface Area:
78.52

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4860810

Name:
(S)-4-(2-(6-ethoxypyridin-3-yl)hydrazinyl)-5-fluoro-N-(1-(5-fluoropyridin-2Show More⌵

Mol. Formula:
C22H20F2N6O

M.W.:
422.44