Compounds

Type:
Unknown

AlogP:
6.87

Polar Surface Area:
23.39

HBA:
3

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA4876761

Name:
3,6-bis(4-isopropoxyphenyl)imidazo[1,2-a]pyridine

Mol. Formula:
C25H26N2O2

M.W.:
386.50

10 activity values

7 unique targets

Type:
Unknown

AlogP:
6.24

Polar Surface Area:
35.76

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4874472

Name:
3,6-bis(4-isopropoxyphenyl)imidazo[1,2-a]pyridine-7-carbonitrile

Mol. Formula:
C26H25N3O2

M.W.:
411.51

10 activity values

Type:
Unknown

AlogP:
6.11

Polar Surface Area:
59.55

HBA:
5

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA4874362

Name:
6-(2-fluoro-4-isopropoxyphenyl)-3-(4-isopropoxyphenyl)imidazo[1,2-a]pyridinShow More⌵

Mol. Formula:
C25H25FN2O2

M.W.:
404.49

Type:
Unknown

AlogP:
6.38

Polar Surface Area:
35.76

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.37

DETAILS

ALA4871905

Name:
6-(4-isopropoxy-3-methylphenyl)-3-(4-isopropoxyphenyl)imidazo[1,2-a]pyridinShow More⌵

Mol. Formula:
C26H28N2O2

M.W.:
400.52

5 activity values

Type:
Unknown

AlogP:
6.55

Polar Surface Area:
35.76

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.37

DETAILS

ALA4870517

Name:
3,5-bis(4-isopropoxyphenyl)-1H-indazole

Mol. Formula:
C25H26N2O2

M.W.:
386.50

Type:
Unknown

AlogP:
6.47

Polar Surface Area:
47.14

HBA:
3

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA4870239

Name:
3,6-bis(4-isopropoxyphenyl)imidazo[1,5-a]pyridine

Mol. Formula:
C25H26N2O2

M.W.:
386.50

Type:
Unknown

AlogP:
6.24

Polar Surface Area:
35.76

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4869681

Name:
1-(4-(6-(4-isopropoxyphenyl)imidazo[1,2-a]pyridin-3-yl)phenyl)ethanone

Mol. Formula:
C24H22N2O2

M.W.:
370.45

Type:
Unknown

AlogP:
5.66

Polar Surface Area:
43.60

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4869270

Name:
3-(4-cyclopropoxyphenyl)-6-(4-isopropoxyphenyl)imidazo[1,2-a]pyridine

Mol. Formula:
C25H24N2O2

M.W.:
384.48

5 activity values

Type:
Unknown

AlogP:
6.00

Polar Surface Area:
35.76

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA4868358

Name:
6-(4-isopropoxy-2-methylphenyl)-3-(4-isopropoxyphenyl)imidazo[1,2-a]pyridinShow More⌵

Mol. Formula:
C26H28N2O2

M.W.:
400.52

Type:
Unknown

AlogP:
6.55

Polar Surface Area:
35.76

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.37

DETAILS

ALA4866634

Name:
3-(3-isopropoxyphenyl)-6-(4-isopropoxyphenyl)imidazo[1,2-a]pyridine

Mol. Formula:
C25H26N2O2

M.W.:
386.50

Type:
Unknown

AlogP:
6.24

Polar Surface Area:
35.76

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4865651

Name:
3,6-bis(4-isopropoxyphenyl)-8-methylimidazo[1,2-a]pyridine

Mol. Formula:
C26H28N2O2

M.W.:
400.52

Type:
Unknown

AlogP:
6.55

Polar Surface Area:
35.76

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.37

DETAILS

ALA4865600

Name:
1,6-bis(4-isopropoxyphenyl)-1H-imidazo[4,5-c]pyridine

Mol. Formula:
C24H25N3O2

M.W.:
387.48

Type:
Unknown

AlogP:
5.66

Polar Surface Area:
49.17

HBA:
5

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4865537

Name:
4-(3-(4-isopropoxyphenyl)imidazo[1,2-a]pyridin-6-yl)benzamide

Mol. Formula:
C23H21N3O2

M.W.:
371.44

Type:
Unknown

AlogP:
4.55

Polar Surface Area:
69.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA4865002

Name:
1,6-bis(4-isopropoxyphenyl)-1H-indazole

Mol. Formula:
C25H26N2O2

M.W.:
386.50

Type:
Unknown

AlogP:
6.27

Polar Surface Area:
36.28

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4864575

Name:
3,6-bis(4-isopropoxyphenyl)-[1,2,4]triazolo[4,3-a]pyridine

Mol. Formula:
C24H25N3O2

M.W.:
387.48

8 activity values

6 unique targets

Type:
Unknown

AlogP:
5.64

Polar Surface Area:
48.65

HBA:
5

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4864499

Name:
6-(1-cyclopropyl-1H-pyrazol-4-yl)-3-(4-isopropoxyphenyl)imidazo[1,2-a]pyridShow More⌵

Mol. Formula:
C22H22N4O

M.W.:
358.45

Type:
Unknown

AlogP:
4.99

Polar Surface Area:
44.35

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4864023

Name:
1-(4-(3-(4-isopropoxyphenyl)imidazo[1,2-a]pyridin-6-yl)phenyl)cyclopropanamShow More⌵

Mol. Formula:
C25H25N3O

M.W.:
383.50

5 activity values

Type:
Unknown

AlogP:
5.40

Polar Surface Area:
52.55

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4863098

Name:
3,6-bis(4-isopropoxyphenyl)imidazo[1,2-a]pyrazine

Mol. Formula:
C24H25N3O2

M.W.:
387.48

Type:
Unknown

AlogP:
5.64

Polar Surface Area:
48.65

HBA:
5

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4862268

Name:
6-(4-fluorophenyl)-3-(4-isopropoxyphenyl)imidazo[1,2-a]pyridine

Mol. Formula:
C22H19FN2O

M.W.:
346.41