Compounds

ALA5272375

Name:
4-amino-3-(3,5-dimethylbenzofuran-2-yl)-2-(1-methacryloylpiperidin-4-yl)-2HShow More⌵

Mol. Formula:
C24H26N6O3

M.W.:
446.51

Type:
---

AlogP:
3.47

Polar Surface Area:
123.04

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5271701

Name:
4-amino-3-(3,5-dimethylbenzofuran-2-yl)-2-(1-propioloylpiperidin-4-yl)-2H-pShow More⌵

Mol. Formula:
C23H22N6O3

M.W.:
430.47

Type:
---

AlogP:
2.53

Polar Surface Area:
123.04

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA5271661

Name:
2-(1-acryloylpiperidin-4-yl)-4-amino-3-(4-methoxy-3-methylbenzofuran-2-yl)-Show More⌵

Mol. Formula:
C23H24N6O4

M.W.:
448.48

Type:
---

AlogP:
2.78

Polar Surface Area:
132.27

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5271113

Name:
(E)-4-amino-3-(3,5-dimethylbenzofuran-2-yl)-2-(1-(2-methylbut-2-enoyl)piperShow More⌵

Mol. Formula:
C25H28N6O3

M.W.:
460.54

Type:
---

AlogP:
3.86

Polar Surface Area:
123.04

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5271030

Name:
(S)-1-(3-(8-Amino-1-(5-bromo-7-methoxybenzo[b]thiophen-2-yl)imidazo[1,5-a]pShow More⌵

Mol. Formula:
C22H20BrN5O2S

M.W.:
498.41

Type:
---

AlogP:
4.47

Polar Surface Area:
85.75

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5270592

Name:
(Rac)-2-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-methoxy-3-methylbenzofuran-Show More⌵

Mol. Formula:
C23H24N6O4

M.W.:
448.48

Type:
---

AlogP:
2.78

Polar Surface Area:
132.27

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5270255

Name:
(Rac)-(E)-4-amino-3-(3,5-dimethylbenzofuran-2-yl)-2-(1-(2-methylbut-2-enoylShow More⌵

Mol. Formula:
C25H28N6O3

M.W.:
460.54

Type:
---

AlogP:
3.86

Polar Surface Area:
123.04

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5270198

Name:
2-(1-acryloylpiperidin-4-yl)-4-amino-3-(5-chloro-3-methylbenzofuran-2-yl)-2Show More⌵

Mol. Formula:
C22H21ClN6O3

M.W.:
452.90

Type:
---

AlogP:
3.43

Polar Surface Area:
123.04

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5270144

Name:
(Rac)-4-amino-3-(3,5-dimethylbenzofuran-2-yl)-2-(1-propionylpiperidin-3-yl)Show More⌵

Mol. Formula:
C23H26N6O3

M.W.:
434.50

Type:
---

AlogP:
3.31

Polar Surface Area:
123.04

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5269917

Name:
N-(6-(2,6-dichloro-3,5-dimethoxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-4-(Show More⌵

Mol. Formula:
C27H28Cl2N6O3

M.W.:
555.47

Type:
---

AlogP:
5.39

Polar Surface Area:
104.40

HBA:
7

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA5269439

Name:
2-(1-acryloylpiperidin-4-yl)-4-amino-3-(6-methoxy-3-methylbenzofuran-2-yl)-Show More⌵

Mol. Formula:
C23H24N6O4

M.W.:
448.48

Type:
---

AlogP:
2.78

Polar Surface Area:
132.27

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5269341

Name:
6-(1-methyl-1H-pyrazol-4-yl)-1-(phenylsulfonyl)-1H-pyrazolo[3,4-b]pyrazine

Mol. Formula:
C15H12N6O2S

M.W.:
340.37

Type:
---

AlogP:
1.46

Polar Surface Area:
95.56

HBA:
8

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA5269216

Name:
(Rac)-2-(1-acryloylpiperidin-3-yl)-4-amino-3-(4,6-dimethoxy-3-methylbenzofuShow More⌵

Mol. Formula:
C24H26N6O5

M.W.:
478.51

Type:
---

AlogP:
2.79

Polar Surface Area:
141.50

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5269023

Name:
(Rac)-(E)-4-amino-3-(3,5-dimethylbenzofuran-2-yl)-2-(1-(pent-2-enoyl)piperiShow More⌵

Mol. Formula:
C25H28N6O3

M.W.:
460.54

Type:
---

AlogP:
3.86

Polar Surface Area:
123.04

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5268906

Name:
(Rac)-2-(1-acryloylpiperidin-3-yl)-4-amino-3-(5-chloro-3-methylbenzofuran-2Show More⌵

Mol. Formula:
C22H21ClN6O3

M.W.:
452.90

Type:
---

AlogP:
3.43

Polar Surface Area:
123.04

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5267988

Name:
3-(7-Methoxybenzo[b]thiophen-2-yl)-1-(piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrShow More⌵

Mol. Formula:
C19H20N6OS

M.W.:
380.48

Type:
---

AlogP:
3.22

Polar Surface Area:
90.88

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5282211

Name:
4-amino-3-(3,5-dimethylbenzofuran-2-yl)-2-(1-(4-hydroxybut-2-ynoyl)piperidiShow More⌵

Mol. Formula:
C24H24N6O4

M.W.:
460.49

Type:
---

AlogP:
1.89

Polar Surface Area:
143.27

HBA:
8

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA5281404

Name:
2-(1-acryloylpiperidin-4-yl)-4-amino-3-(5-methoxy-3-methylbenzofuran-2-yl)-Show More⌵

Mol. Formula:
C23H24N6O4

M.W.:
448.48

Type:
---

AlogP:
2.78

Polar Surface Area:
132.27

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5281147

Name:
(Rac)-4-amino-3-(3,5-dimethylbenzofuran-2-yl)-2-(1-(pent-2-ynoyl)piperidin-Show More⌵

Mol. Formula:
C25H26N6O3

M.W.:
458.52

Type:
---

AlogP:
3.31

Polar Surface Area:
123.04

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5278114

Name:
(Rac)-4-amino-3-(3,5-dimethylbenzofuran-2-yl)-2-(1-(4-hydroxybut-2-ynoyl)piShow More⌵

Mol. Formula:
C24H24N6O4

M.W.:
460.49

Type:
---

AlogP:
1.89

Polar Surface Area:
143.27

HBA:
8

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.39

DETAILS