Compounds

ALA4878188

Name:
(R)-3-amino-6-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenylShow More⌵

Mol. Formula:
C23H23F2N5O3

M.W.:
455.47

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.12

Polar Surface Area:
130.23

HBA:
6

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4876496

Name:
(R)-2-amino-N-tert-butyl-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2Show More⌵

Mol. Formula:
C25H26F2N4O3

M.W.:
468.50

2 activity values

2 unique targets

Type:
Unknown

AlogP:
4.12

Polar Surface Area:
117.34

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4876223

Name:
(R)-2-amino-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenylShow More⌵

Mol. Formula:
C23H22F2N4O3

M.W.:
440.45

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.29

Polar Surface Area:
108.55

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA4875875

Name:
(R)-2-amino-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenylShow More⌵

Mol. Formula:
C22H20F2N4O3

M.W.:
426.42

2 activity values

2 unique targets

Type:
Unknown

AlogP:
2.95

Polar Surface Area:
117.34

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4870780

Name:
(R)-2-amino-5-(4-(2-hydroxy-2-m-tolylacetamido)-2-methylphenyl)-N-isopropylShow More⌵

Mol. Formula:
C25H28N4O3

M.W.:
432.52

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.76

Polar Surface Area:
117.34

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA4870565

Name:
(R)-2-amino-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methoxyphenyShow More⌵

Mol. Formula:
C24H24F2N4O4

M.W.:
470.48

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.43

Polar Surface Area:
126.57

HBA:
6

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4870495

Name:
(R)-2-amino-5-(4-(2-hydroxy-2-phenylacetamido)-2-methylphenyl)-N-isopropylnShow More⌵

Mol. Formula:
C24H26N4O3

M.W.:
418.50

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.45

Polar Surface Area:
117.34

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA4870100

Name:
(R)-isopropyl 2-amino-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-meShow More⌵

Mol. Formula:
C24H23F2N3O4

M.W.:
455.46

2 activity values

2 unique targets

Type:
Unknown

AlogP:
4.15

Polar Surface Area:
114.54

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4869882

Name:
(R)-2-amino-N-cyclopropyl-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-Show More⌵

Mol. Formula:
C24H22F2N4O3

M.W.:
452.46

13 activity values

4 unique targets

Type:
Unknown

AlogP:
3.48

Polar Surface Area:
117.34

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA4868021

Name:
(R)-2-amino-5-(4-(2-hydroxy-2-phenylpropanamido)-2-methylphenyl)-N-isopropyShow More⌵

Mol. Formula:
C25H28N4O3

M.W.:
432.52

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.62

Polar Surface Area:
117.34

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA4866245

Name:
2-amino-N-isopropyl-5-(2-methyl-4-(2-phenylacetamido)phenyl)nicotinamide

Mol. Formula:
C24H26N4O2

M.W.:
402.50

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.96

Polar Surface Area:
97.11

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4865268

Name:
2-amino-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenyl)nicShow More⌵

Mol. Formula:
C21H17F2N3O4

M.W.:
413.38

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.29

Polar Surface Area:
125.54

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA4863698

Name:
(R)-2-amino-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenylShow More⌵

Mol. Formula:
C23H22F2N4O3

M.W.:
440.45

13 activity values

4 unique targets

Type:
Unknown

AlogP:
3.34

Polar Surface Area:
117.34

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA4862478

Name:
(R)-2-amino-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenylShow More⌵

Mol. Formula:
C24H24F2N4O3

M.W.:
454.48

17 activity values

4 unique targets

Type:
Unknown

AlogP:
3.73

Polar Surface Area:
117.34

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4861671

Name:
(R)-3-amino-6-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenylShow More⌵

Mol. Formula:
C23H23F2N5O3

M.W.:
455.47

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.12

Polar Surface Area:
130.23

HBA:
6

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4858598

Name:
(R)-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenyl)-N-isopShow More⌵

Mol. Formula:
C25H26F2N4O3

M.W.:
468.50

2 activity values

2 unique targets

Type:
Unknown

AlogP:
4.19

Polar Surface Area:
103.35

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4858308

Name:
(R)-2-amino-5-(4-(2-(3-ethylphenyl)-2-hydroxyacetamido)-2-methylphenyl)-N-iShow More⌵

Mol. Formula:
C26H30N4O3

M.W.:
446.55

2 activity values

2 unique targets

Type:
Unknown

AlogP:
4.01

Polar Surface Area:
117.34

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA4857782

Name:
(R)-2-amino-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-ethylphenyl)Show More⌵

Mol. Formula:
C25H26F2N4O3

M.W.:
468.50

30 activity values

17 unique targets

Type:
Unknown

AlogP:
3.98

Polar Surface Area:
117.34

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4856844

Name:
phenyl 4-(6-amino-5-(isopropylcarbamoyl)pyridin-3-yl)-3-methylphenylcarbamaShow More⌵

Mol. Formula:
C23H24N4O3

M.W.:
404.47

2 activity values

2 unique targets

Type:
Unknown

AlogP:
4.39

Polar Surface Area:
106.34

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4854504

Name:
(R)-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenyl)-N-isopShow More⌵

Mol. Formula:
C24H23F2N3O3

M.W.:
439.46

2 activity values

2 unique targets

Type:
Unknown

AlogP:
4.15

Polar Surface Area:
91.32

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.54

DETAILS