Compounds

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ALA4875968
Name:
N-(4-(6-bromo-1-methyl-1H-indazol-5-yloxy)phenyl)-5-(4-fluorophenyl)-2-(metShow More⌵
Mol. Formula:
C25H18BrFN4O3S
M.W.:
553.41
23 activity values
22 unique targets
Type:
Unknown
AlogP:
6.90
Polar Surface Area:
82.18
HBA:
7
HBD:
1
#RO5 Violations:
2
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.23
DETAILS
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ALA4874174
Name:
4-(4-(5-(4-fluorophenyl)-2-(methylthio)-1H-imidazole-4-carboxamido)phenoxy)Show More⌵
Mol. Formula:
C24H20FN5O3S
M.W.:
477.52
30 activity values
26 unique targets
Type:
Unknown
AlogP:
4.74
Polar Surface Area:
109.00
HBA:
6
HBD:
3
#RO5 Violations:
---
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.33
DETAILS
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ALA4870763
Name:
5-(4-fluorophenyl)-N-(4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)-2-(trifShow More⌵
Mol. Formula:
C24H16F4N4O3S
M.W.:
516.48
21 activity values
20 unique targets
Type:
Unknown
AlogP:
5.77
Polar Surface Area:
93.21
HBA:
6
HBD:
2
#RO5 Violations:
2
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.32
DETAILS
CLOSE
ALA4859179
Name:
5-(4-fluorophenyl)-N-(4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)-2-(methShow More⌵
Mol. Formula:
C24H19FN4O4S
M.W.:
478.51
31 activity values
27 unique targets
Type:
Unknown
AlogP:
5.00
Polar Surface Area:
106.35
HBA:
7
HBD:
2
#RO5 Violations:
1
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.36
DETAILS
CLOSE
ALA4855979
Name:
5-(4-fluorophenyl)-2-(methylamino)-N-(4-(2-(methylcarbamoyl)pyridin-4-yloxyShow More⌵
Mol. Formula:
C24H20FN5O3S
M.W.:
477.52
23 activity values
22 unique targets
Type:
Unknown
AlogP:
4.79
Polar Surface Area:
105.24
HBA:
7
HBD:
3
#RO5 Violations:
---
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.35
DETAILS
CLOSE
ALA4855209
Name:
N-(3-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)-5-(4-fluorophenylShow More⌵
Mol. Formula:
C24H18F2N4O4S
M.W.:
496.50
23 activity values
22 unique targets
Type:
Unknown
AlogP:
5.14
Polar Surface Area:
106.35
HBA:
7
HBD:
2
#RO5 Violations:
1
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.34
DETAILS
CLOSE
ALA4853006
Name:
4-(4-(5-(4-fluorophenyl)-2H-1,2,3-triazole-4-carboxamido)phenoxy)-N-methylpShow More⌵
Mol. Formula:
C22H17FN6O3
M.W.:
432.42
23 activity values
22 unique targets
Type:
Unknown
AlogP:
3.41
Polar Surface Area:
121.89
HBA:
6
HBD:
3
#RO5 Violations:
---
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.43
DETAILS
CLOSE
ALA4850066
Name:
5-(4-fluorophenyl)-N-(4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)-2-(methShow More⌵
Mol. Formula:
C24H19FN4O5S2
M.W.:
526.57
30 activity values
27 unique targets
Type:
Unknown
AlogP:
4.15
Polar Surface Area:
127.35
HBA:
8
HBD:
2
#RO5 Violations:
1
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.37
DETAILS
CLOSE