Compounds

ALA5271931

Name:
N-(3-Bromo-1H-indazol-5-yl)-4,5-dimethyl-4,7-dihydrotetrazolo[1,5-a]pyrimidShow More⌵

Mol. Formula:
C14H13BrN8O

M.W.:
389.22

Type:
---

AlogP:
1.67

Polar Surface Area:
104.62

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5271437

Name:
(R)-N-(1-Aminoisoquinolin-6-yl)-4,5,7-trimethyl-4,7-dihydrotetrazolo[1,5-a]Show More⌵

Mol. Formula:
C17H18N8O

M.W.:
350.39

Type:
---

AlogP:
1.73

Polar Surface Area:
114.85

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA5270706

Name:
4,5,7,7-Tetramethyl-N-(3-(2-morpholinopyridin-4-yl)-1H-indazol-5-yl)-4,7-diShow More⌵

Mol. Formula:
C25H28N10O2

M.W.:
500.57

Type:
---

AlogP:
2.55

Polar Surface Area:
129.98

HBA:
10

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5269009

Name:
N-(1H-Indazol-5-yl)-5-methyl-4-[2-(morpholin-4-yl)ethyl]-4H,7H-[1,2,3,4]tetShow More⌵

Mol. Formula:
C19H23N9O2

M.W.:
409.45

Type:
---

AlogP:
0.61

Polar Surface Area:
117.09

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5268380

Name:
(2R,6S)-2,6-dimethyl-4-(4-(6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,5-a]pyridiShow More⌵

Mol. Formula:
C22H24N6O

M.W.:
388.48

Type:
---

AlogP:
3.41

Polar Surface Area:
60.48

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5267951

Name:
4-Ethyl-N-(1H-indazol-5-yl)-5-methyl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-Show More⌵

Mol. Formula:
C15H16N8O

M.W.:
324.35

Type:
---

AlogP:
1.30

Polar Surface Area:
104.62

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.75

DETAILS

ALA5282583

Name:
(R)-2-(1-(6-(6-(1H-pyrazol-5-yl)-1H-indazol-1-yl)pyrimidin-4-yl)pyrrolidin-Show More⌵

Mol. Formula:
C21H23N7O

M.W.:
389.46

Type:
---

AlogP:
2.80

Polar Surface Area:
95.75

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA5281154

Name:
(R)-4,5,7-Trimethyl-N-(3-(2-morpholinopyridin-4-yl)-1H-indazol-5-yl)-4,7-diShow More⌵

Mol. Formula:
C24H26N10O2

M.W.:
486.54

Type:
---

AlogP:
2.37

Polar Surface Area:
129.98

HBA:
10

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5280577

Name:
4,5,7,7-Tetramethyl-N-(3-methyl-1H-indazol-5-yl)-4,7-dihydrotetrazolo[1,5-aShow More⌵

Mol. Formula:
C17H20N8O

M.W.:
352.40

Type:
---

AlogP:
1.96

Polar Surface Area:
104.62

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA5280528

Name:
4,5-Dimethyl-N-(3-methyl-1H-indol-5-yl)-4,7-dihydrotetrazolo[1,5-a]pyrimidiShow More⌵

Mol. Formula:
C16H17N7O

M.W.:
323.36

Type:
---

AlogP:
1.83

Polar Surface Area:
91.73

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.75

DETAILS

ALA5280373

Name:
4,5,7,7-Tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-4,7-dihydrotetrazolo[1,5-aShow More⌵

Mol. Formula:
C22H22N8O

M.W.:
414.47

Type:
---

AlogP:
3.31

Polar Surface Area:
104.62

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5280273

Name:
N-(3-Butyramido-1H-indazol-5-yl)-4,5-dimethyl-4,7-dihydrotetrazolo[1,5-a]pyShow More⌵

Mol. Formula:
C18H21N9O2

M.W.:
395.43

Type:
---

AlogP:
1.65

Polar Surface Area:
133.72

HBA:
8

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5279816

Name:
(R)-4,5,7-Trimethyl-N-(3-methyl-1H-indazol-5-yl)-4,7-dihydrotetrazolo[1,5-aShow More⌵

Mol. Formula:
C16H18N8O

M.W.:
338.38

Type:
---

AlogP:
1.78

Polar Surface Area:
104.62

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5279765

Name:
(S)-4,5,7-Trimethyl-N-(3-methyl-1H-indazol-5-yl)-4,7-dihydrotetrazolo[1,5-aShow More⌵

Mol. Formula:
C16H18N8O

M.W.:
338.38

Type:
---

AlogP:
1.78

Polar Surface Area:
104.62

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5279418

Name:
N-(1H-Indazol-5-yl)-4,5-dimethyl-4H,7H-[1,2,3,4]tetrazolo[1,5-a]pyrimidine-Show More⌵

Mol. Formula:
C14H14N8O

M.W.:
310.32

Type:
---

AlogP:
0.91

Polar Surface Area:
104.62

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA5279036

Name:
4,5-Dimethyl-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)-4,7-dihydrotetrazolo[1,5-Show More⌵

Mol. Formula:
C19H17N9O

M.W.:
387.41

Type:
---

AlogP:
1.97

Polar Surface Area:
117.51

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA5278535

Name:
3-(1-(6-((3R,5S)-3,4,5-trimethylpiperazin-1-yl)pyrimidin-4-yl)-1H-indazol-6Show More⌵

Mol. Formula:
C21H25N7

M.W.:
375.48

Type:
---

AlogP:
2.80

Polar Surface Area:
73.87

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5278514

Name:
N-(1H-Indazol-5-yl)-4-methyl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxShow More⌵

Mol. Formula:
C13H12N8O

M.W.:
296.29

Type:
---

AlogP:
0.52

Polar Surface Area:
104.62

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5277441

Name:
(R)-4,5,7-Trimethyl-N-(3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)Show More⌵

Mol. Formula:
C16H18N8O2

M.W.:
354.37

Type:
---

AlogP:
0.78

Polar Surface Area:
113.73

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5277180

Name:
(S)-N-(1H-Indazol-5-yl)-4,5,7-trimethyl-4,7-dihydrotetrazolo[1,5-a]pyrimidiShow More⌵

Mol. Formula:
C15H16N8O

M.W.:
324.35

Type:
---

AlogP:
1.47

Polar Surface Area:
104.62

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.74

DETAILS