Compounds

Type:
Unknown

AlogP:
2.66

Polar Surface Area:
144.72

HBA:
10

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA4799728

Name:
5-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((4-(methylsulfonyl)piperazin-Show More⌵

Mol. Formula:
C24H29F3N8O3S

M.W.:
566.61

Type:
Unknown

AlogP:
1.84

Polar Surface Area:
122.19

HBA:
10

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA4791280

Name:
(S)-5-(4-(3-methylmorpholino)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)pShow More⌵

Mol. Formula:
C23H29F3N8O3S

M.W.:
554.60

Type:
Unknown

AlogP:
1.69

Polar Surface Area:
122.19

HBA:
10

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4784118

Name:
1-methyl-3-(5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrShow More⌵

Mol. Formula:
C24H30F3N9O4S

M.W.:
597.62

Type:
Unknown

AlogP:
1.48

Polar Surface Area:
137.30

HBA:
10

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4783228

Name:
1-(4-fluorophenyl)-3-(5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morShow More⌵

Mol. Formula:
C29H31F4N9O4S

M.W.:
677.69

Type:
Unknown

AlogP:
3.51

Polar Surface Area:
137.30

HBA:
10

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA4781518

Name:
1-ethyl-3-(5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrShow More⌵

Mol. Formula:
C25H32F3N9O4S

M.W.:
611.65

Type:
Unknown

AlogP:
1.87

Polar Surface Area:
137.30

HBA:
10

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA4779801

Name:
ethyl 5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[1Show More⌵

Mol. Formula:
C25H31F3N8O5S

M.W.:
612.64

Type:
Unknown

AlogP:
2.29

Polar Surface Area:
134.50

HBA:
11

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4761702

Name:
5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[1,2-f][Show More⌵

Mol. Formula:
C22H27F3N8O3S

M.W.:
540.57

Type:
Unknown

AlogP:
1.31

Polar Surface Area:
122.19

HBA:
10

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA4760391

Name:
phenyl 5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[Show More⌵

Mol. Formula:
C29H31F3N8O5S

M.W.:
660.68

Type:
Unknown

AlogP:
3.33

Polar Surface Area:
134.50

HBA:
11

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA4742751

Name:
1-(4-(4-(dimethylamino)piperidine-1-carbonyl)phenyl)-3-(4-(6-((4-(methylsulShow More⌵

Mol. Formula:
C37H48N10O5S

M.W.:
744.92

Type:
Unknown

AlogP:
3.12

Polar Surface Area:
147.96

HBA:
11

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA4740055

Name:
N-(5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[1,2-Show More⌵

Mol. Formula:
C25H29F3N8O4S

M.W.:
594.62

Type:
Unknown

AlogP:
1.85

Polar Surface Area:
125.27

HBA:
10

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA4648964

Name:
2-[6-amino-4-(trifluoromethyl)-3-pyridyl]-N-[3-(dimethylamino)propyl]-4-morShow More⌵

Mol. Formula:
C22H27F3N8O2

M.W.:
492.51

Type:
Unknown

AlogP:
1.91

Polar Surface Area:
113.91

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4648855

Name:
[2-[6-amino-4-(trifluoromethyl)-3-pyridyl]-4-morpholino-pyrrolo[2,1-f][1,2,Show More⌵

Mol. Formula:
C23H27F3N8O2

M.W.:
504.52

Type:
Unknown

AlogP:
2.01

Polar Surface Area:
105.12

HBA:
9

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4647790

Name:
2-[6-amino-4-(trifluoromethyl)-3-pyridyl]-N-(3-methoxypropyl)-4-morpholino-Show More⌵

Mol. Formula:
C21H24F3N7O3

M.W.:
479.46

Type:
Unknown

AlogP:
2.00

Polar Surface Area:
119.90

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA4646999

Name:
2-[6-amino-4-(trifluoromethyl)-3-pyridyl]-N-[2-(dimethylamino)ethyl]-7-methShow More⌵

Mol. Formula:
C22H27F3N8O2

M.W.:
492.51

Type:
Unknown

AlogP:
1.83

Polar Surface Area:
113.91

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA4646573

Name:
2-[6-amino-4-(trifluoromethyl)-3-pyridyl]-N,N-diethyl-4-morpholino-pyrrolo[Show More⌵

Mol. Formula:
C21H24F3N7O2

M.W.:
463.46

Type:
Unknown

AlogP:
2.71

Polar Surface Area:
101.88

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA4645159

Name:
[2-[6-amino-4-(trifluoromethyl)-3-pyridyl]-4-morpholino-pyrrolo[2,1-f][1,2,Show More⌵

Mol. Formula:
C21H22F3N7O3

M.W.:
477.45

Type:
Unknown

AlogP:
1.70

Polar Surface Area:
111.11

HBA:
9

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA4644602

Name:
[2-[6-amino-4-(trifluoromethyl)-3-pyridyl]-7-methyl-4-morpholino-pyrrolo[2,Show More⌵

Mol. Formula:
C25H31F3N8O2

M.W.:
532.57

Type:
Unknown

AlogP:
2.70

Polar Surface Area:
105.12

HBA:
9

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA4643948

Name:
2-[6-amino-4-(trifluoromethyl)-3-pyridyl]-N-butyl-4-morpholino-pyrrolo[2,1-Show More⌵

Mol. Formula:
C21H24F3N7O2

M.W.:
463.46