Compounds

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ALA4551577
Name:
4,4'-(pyridine-3,5-diyl)bis(2,6-difluorophenol)
Mol. Formula:
C17H9F4NO2
M.W.:
335.26
1 activity values
1 unique targets
Type:
Unknown
AlogP:
4.38
Polar Surface Area:
53.35
HBA:
3
HBD:
2
#RO5 Violations:
---
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.68
DETAILS
CLOSE
ALA4474049
Name:
4,4'-(2,6-diaminopyridine-3,5-diyl)bis(2,6-difluorophenol)
Mol. Formula:
C17H11F4N3O2
M.W.:
365.29
1 activity values
1 unique targets
Type:
Unknown
AlogP:
3.55
Polar Surface Area:
105.39
HBA:
5
HBD:
4
#RO5 Violations:
---
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.52
DETAILS
CLOSE
ALA4467571
Name:
4-(6-amino-5-(3,5-difluoro-4-hydroxyphenyl)pyridin-3-yl)benzenesulfonamide
Mol. Formula:
C17H13F2N3O3S
M.W.:
377.37
6 activity values
3 unique targets
Type:
Unknown
AlogP:
2.63
Polar Surface Area:
119.30
HBA:
5
HBD:
3
#RO5 Violations:
---
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.65
DETAILS
CLOSE
ALA4466422
Name:
4,4'-(2-amino-6-methylpyridine-3,5-diyl)bis(2,6-difluorophenol)
Mol. Formula:
C18H12F4N2O2
M.W.:
364.30
1 activity values
1 unique targets
Type:
Unknown
AlogP:
4.27
Polar Surface Area:
79.37
HBA:
4
HBD:
3
#RO5 Violations:
---
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.59
DETAILS
CLOSE
ALA4452098
Name:
4-(2-amino-5-(benzo[d]thiazol-6-yl)pyridin-3-yl)-2,6-difluorophenol
Mol. Formula:
C18H11F2N3OS
M.W.:
355.37
3 activity values
2 unique targets
Type:
Unknown
AlogP:
4.59
Polar Surface Area:
72.03
HBA:
5
HBD:
2
#RO5 Violations:
---
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.55
DETAILS
CLOSE
ALA4436323
Name:
4,4'-(2-aminopyridine-3,5-diyl)bis(2,6-difluorophenol)
Mol. Formula:
C17H10F4N2O2
M.W.:
350.27
3 activity values
2 unique targets
Type:
Unknown
AlogP:
3.97
Polar Surface Area:
79.37
HBA:
4
HBD:
3
#RO5 Violations:
---
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.61
DETAILS
CLOSE
VRK-IN-1
Name:
4,4'-(2-methylpyridine-3,5-diyl)bis(2,6-difluorophenol)
Mol. Formula:
C18H11F4NO2
M.W.:
349.28
6 activity values
3 unique targets
Type:
Unknown
AlogP:
4.69
Polar Surface Area:
53.35
HBA:
3
HBD:
2
#RO5 Violations:
---
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.66
DETAILS
CLOSE