Compounds

ALA4877978

Name:
1-(1H-benzo[d]imidazol-2-yl)-3-methyl-4-p-tolyl-1H-pyrazol-5-ol

Mol. Formula:
C18H16N4O

M.W.:
304.35

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.74

Polar Surface Area:
66.73

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA4875827

Name:
1-(1H-benzo[d]imidazol-2-yl)-3-methyl-1H-pyrazol-5-amine

Mol. Formula:
C11H11N5

M.W.:
213.24

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.64

Polar Surface Area:
72.52

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA4875646

Name:
4-allyl-1-(1H-benzo[d]imidazol-2-yl)-3-methyl-1H-pyrazol-5-ol

Mol. Formula:
C14H14N4O

M.W.:
254.29

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.49

Polar Surface Area:
66.73

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA4874810

Name:
1-(1H-benzo[d]imidazol-2-yl)-3-ethyl-4-phenyl-1H-pyrazol-5-ol

Mol. Formula:
C18H16N4O

M.W.:
304.35

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.68

Polar Surface Area:
66.73

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA4873031

Name:
1-(6-chloropyridazin-3-yl)-3-methyl-4-phenyl-1H-pyrazol-5-ol

Mol. Formula:
C14H11ClN4O

M.W.:
286.72

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.00

Polar Surface Area:
63.83

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA4872349

Name:
2-(5-hydroxy-3-methyl-4-phenyl-1H-pyrazol-1-yl)-1H-benzo[d]imidazole-6-carbShow More⌵

Mol. Formula:
C18H14N4O3

M.W.:
334.33

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.13

Polar Surface Area:
104.03

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA4871154

Name:
2-(4-bromo-1H-pyrazol-1-yl)-1H-benzo[d]imidazole

Mol. Formula:
C10H7BrN4

M.W.:
263.10

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.51

Polar Surface Area:
46.50

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
Y

QED Weighted:
0.73

DETAILS

ALA4870552

Name:
3-(1-(1H-benzo[d]imidazol-2-yl)-5-hydroxy-4-methyl-1H-pyrazol-3-yl)propanoiShow More⌵

Mol. Formula:
C14H14N4O3

M.W.:
286.29

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.78

Polar Surface Area:
104.03

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA4866724

Name:
3-(1-(1H-benzo[d]imidazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl)-N,N-dimShow More⌵

Mol. Formula:
C16H19N5O2

M.W.:
313.36

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.78

Polar Surface Area:
87.04

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA4865114

Name:
3-methyl-1-(1-methyl-1H-benzo[d]imidazol-2-yl)-4-phenyl-1H-pyrazol-5-ol

Mol. Formula:
C18H16N4O

M.W.:
304.35

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.44

Polar Surface Area:
55.87

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA4862624

Name:
3-(1-(1H-benzo[d]imidazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl)-N-methyShow More⌵

Mol. Formula:
C15H17N5O2

M.W.:
299.33

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.44

Polar Surface Area:
95.83

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA4861268

Name:
Methyl 3-(1-(1H-benzo[d]imidazol-2-yl)-5-hydroxy-3-methyl-1H-pyrozol-4-yl)pShow More⌵

Mol. Formula:
C15H16N4O3

M.W.:
300.32

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.87

Polar Surface Area:
93.03

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA4857264

Name:
2-(1-(1H-Benzo[d]imidazol-2-yl)-5-hydroxy-1H-pyrazol-3-yl)acetic Acid

Mol. Formula:
C12H10N4O3

M.W.:
258.24

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.08

Polar Surface Area:
104.03

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA4856042

Name:
1-(1H-benzo[d]imidazol-2-yl)-3-methyl-4-propyl-1H-pyrazol-5-ol

Mol. Formula:
C14H16N4O

M.W.:
256.31

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.72

Polar Surface Area:
66.73

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA4854761

Name:
1-(1H-benzo[d]imidazol-2-yl)-4-(3-(dimethylamino)propyl)-3-methyl-1H-pyrazoShow More⌵

Mol. Formula:
C16H21N5O

M.W.:
299.38

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.26

Polar Surface Area:
69.97

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA4854213

Name:
4-allyl-3-methyl-1-(pyridin-2-yl)-1H-pyrazol-5-ol

Mol. Formula:
C12H13N3O

M.W.:
215.26

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.01

Polar Surface Area:
50.94

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA4852545

Name:
3-(1-(1H-benzo[d]imidazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl)propanoiShow More⌵

Mol. Formula:
C14H14N4O3

M.W.:
286.29

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.78

Polar Surface Area:
104.03

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA4852369

Name:
1-(1H-benzo[d]imidazol-2-yl)-3-methyl-4-(3-(methylamino)propyl)-1H-pyrazol-Show More⌵

Mol. Formula:
C15H19N5O

M.W.:
285.35

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.91

Polar Surface Area:
78.76

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA4851617

Name:
Methyl 3-(1-(1H-benzo[d]imidazol-2-yl)-5-hydroxy-4-methyl-1H-pyrazol-3-yl)pShow More⌵

Mol. Formula:
C15H16N4O3

M.W.:
300.32

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.87

Polar Surface Area:
93.03

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA4848475

Name:
1-(1H-benzo[d]imidazol-2-yl)-3-butyl-4-phenyl-1H-pyrazol-5-ol

Mol. Formula:
C20H20N4O

M.W.:
332.41

1 activity values

1 unique targets

Type:
Unknown

AlogP:
4.46

Polar Surface Area:
66.73

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.57

DETAILS