Compounds

ALA5267614

Name:
N-(4-(6-methylbenzo[d]thiazol-2-yl)phenyl)-2-(2-nitrophenyl)acetamide

Mol. Formula:
C22H17N3O3S

M.W.:
403.46

Type:
---

AlogP:
5.36

Polar Surface Area:
85.13

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA5267562

Name:
N-(2-Fluorophenyl)-4-hydroxy-N-isobutyl-2-(tetrahydro-2H-pyran-4-yl)chromanShow More⌵

Mol. Formula:
C24H30FNO5S

M.W.:
463.57

Type:
---

AlogP:
4.29

Polar Surface Area:
76.07

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5267483

Name:
2-(4-(Ethylsulfonyl)phenyl)-N-(4-(1-(3-fluorobenzyl)-6-methyl-1H-benzo[d]imShow More⌵

Mol. Formula:
C31H28FN3O3S

M.W.:
541.65

Type:
---

AlogP:
6.17

Polar Surface Area:
81.06

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA5267381

Name:
N-((5-(Ethylsulfonyl)pyridin-2-yl)methyl)-4-hydroxy-N-isobutyl-2-(tetrahydrShow More⌵

Mol. Formula:
C26H36N2O7S2

M.W.:
552.72

Type:
---

AlogP:
3.33

Polar Surface Area:
123.10

HBA:
8

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5267150

Name:
N-(2,4-dimethylphenyl)-N-isobutyl-2-oxo-1-((tetrahydro-2H-pyran-4-yl)methylShow More⌵

Mol. Formula:
C25H33N3O4S

M.W.:
471.62

Type:
---

AlogP:
4.22

Polar Surface Area:
84.40

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA5267026

Name:
Methyl 4-((2-(4-(2-(4-(ethylsulfonyl)phenyl)acetamido)phenyl)-6-methyl-1H-bShow More⌵

Mol. Formula:
C33H31N3O5S

M.W.:
581.69

Type:
---

AlogP:
5.82

Polar Surface Area:
107.36

HBA:
7

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA5266973

Name:
2-(4-(Ethylsulfonyl)phenyl)-N-(4-(6-methyl-1-(1-(p-tolyl)ethyl)-1H-benzo[d]Show More⌵

Mol. Formula:
C33H33N3O3S

M.W.:
551.71

Type:
---

AlogP:
6.90

Polar Surface Area:
81.06

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA5266527

Name:
1-(4-Fluorophenyl)-N-(4-(6-methylbenzo[d]thiazol-2-yl)phenyl)methanesulfonaShow More⌵

Mol. Formula:
C21H17FN2O2S2

M.W.:
412.51

Type:
---

AlogP:
5.35

Polar Surface Area:
59.06

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5266304

Name:
N-(4-Ethylphenyl)-N-isobutyl-4-methyl-2-(tetrahydro-2H-pyran-4-yl)chromane-Show More⌵

Mol. Formula:
C27H37NO4S

M.W.:
471.66

Type:
---

AlogP:
5.78

Polar Surface Area:
55.84

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5266226

Name:
(R)-2-(4-(Ethylsulfonyl)phenyl)-N-(4-(1-(1-(4-fluorophenyl)ethyl)-6-(trifluShow More⌵

Mol. Formula:
C32H27F4N3O3S

M.W.:
609.65

Type:
---

AlogP:
7.45

Polar Surface Area:
81.06

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA5266225

Name:
N-(4-Ethylphenyl)-N-isobutyl-1-((tetrahydro-2H-pyran-4-yl)oxy)-2,3-dihydro-Show More⌵

Mol. Formula:
C26H35NO4S

M.W.:
457.64

Type:
---

AlogP:
5.28

Polar Surface Area:
55.84

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5266047

Name:
N-(4-Ethylphenyl)-4-hydroxy-N-isobutyl-2-(1-(methylsulfonyl)piperidin-4-yl)Show More⌵

Mol. Formula:
C27H38N2O6S2

M.W.:
550.74

Type:
---

AlogP:
3.96

Polar Surface Area:
104.22

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5265778

Name:
2-chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide

Mol. Formula:
C16H10ClF6NO2

M.W.:
397.70

Type:
---

AlogP:
4.90

Polar Surface Area:
49.33

HBA:
2

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA5282612

Name:
4-((2-(4-(2-(4-(Ethylsulfonyl)phenyl)acetamido)phenyl)-6-methyl-1H-benzo[d]Show More⌵

Mol. Formula:
C32H29N3O5S

M.W.:
567.67

Type:
---

AlogP:
5.73

Polar Surface Area:
118.36

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA5282591

Name:
N-(4-(1-(2,6-Difluorobenzyl)-6-methyl-1H-benzo[d]imidazol-2-yl)phenyl)-2-(4Show More⌵

Mol. Formula:
C31H27F2N3O3S

M.W.:
559.64

Type:
---

AlogP:
6.31

Polar Surface Area:
81.06

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5282505

Name:
2-(4-((3,5-dimethylisoxazol-4-yl)methoxy)phenyl)-N-((2,4-dimethylphenyl)(phShow More⌵

Mol. Formula:
C29H30N2O3

M.W.:
454.57

Type:
---

AlogP:
5.94

Polar Surface Area:
64.36

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA5282428

Name:
N-(4-Fluorophenyl)-4-hydroxy-N-isobutyl-2-(tetrahydro-2H-pyran-4-yl)chromanShow More⌵

Mol. Formula:
C24H30FNO5S

M.W.:
463.57

Type:
---

AlogP:
4.29

Polar Surface Area:
76.07

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5282157

Name:
2-(4-(Ethylsulfonyl)phenyl)-N-(4-(6-methyl-1-(4-methylphenethyl)-1H-benzo[dShow More⌵

Mol. Formula:
C33H33N3O3S

M.W.:
551.71

Type:
---

AlogP:
6.54

Polar Surface Area:
81.06

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA5282046

Name:
N-(4-Ethylphenyl)-4-hydroxy-N-isobutyl-2-((tetrahydro-2H-pyran-4-yl)methyl)Show More⌵

Mol. Formula:
C27H37NO5S

M.W.:
487.66

Type:
---

AlogP:
5.10

Polar Surface Area:
76.07

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA5281426

Name:
2-(4-(Ethylsulfonyl)phenyl)-N-(4-(1-(4-fluorobenzyl)-6-methyl-1H-benzo[d]imShow More⌵

Mol. Formula:
C31H28FN3O3S

M.W.:
541.65

Type:
---

AlogP:
6.17

Polar Surface Area:
81.06

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.25

DETAILS