Compounds

ALA5269635

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(N-phenyl-3-carbamoylphenyShow More⌵

Mol. Formula:
C29H30N4O10

M.W.:
594.58

Type:
---

AlogP:
-1.75

Polar Surface Area:
218.59

HBA:
12

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA5268197

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(N-benzenesulfonyl-3-aminoShow More⌵

Mol. Formula:
C28H30N4O11S

M.W.:
630.63

Type:
---

AlogP:
-2.20

Polar Surface Area:
235.66

HBA:
13

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.13

DETAILS

ALA5279603

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(4-aminophenyl)-6,7-dideoxShow More⌵

Mol. Formula:
C22H26N4O9

M.W.:
490.47

Type:
---

AlogP:
-3.42

Polar Surface Area:
215.51

HBA:
12

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.16

DETAILS

ALA5278736

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(4-N-benzoylaminophenyl)-6Show More⌵

Mol. Formula:
C29H30N4O10

M.W.:
594.58

Type:
---

AlogP:
-1.75

Polar Surface Area:
218.59

HBA:
12

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA5277965

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(3-N-benzoylaminophenyl)-6Show More⌵

Mol. Formula:
C29H30N4O10

M.W.:
594.58

Type:
---

AlogP:
-1.75

Polar Surface Area:
218.59

HBA:
12

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA5274543

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(6,7-dideoxy-7-(2-methylphenyShow More⌵

Mol. Formula:
C23H27N3O9

M.W.:
489.48

Type:
---

AlogP:
-2.69

Polar Surface Area:
189.49

HBA:
11

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5274523

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(2-aminophenyl)-6,7-dideoxShow More⌵

Mol. Formula:
C22H26N4O9

M.W.:
490.47

Type:
---

AlogP:
-3.42

Polar Surface Area:
215.51

HBA:
12

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.16

DETAILS

ALA5273400

Name:
1-[(2R,3R,4S,5S)-5-[(1S)-1-{[(2R,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxoShow More⌵

Mol. Formula:
C22H29N3O9

M.W.:
479.49

Type:
---

AlogP:
-2.42

Polar Surface Area:
189.49

HBA:
11

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5287014

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(N-phenyl-4-carbamoylphenyShow More⌵

Mol. Formula:
C29H30N4O10

M.W.:
594.58

Type:
---

AlogP:
-1.75

Polar Surface Area:
218.59

HBA:
12

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA5286726

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(2-carboxyphenyl)-6,7-dideShow More⌵

Mol. Formula:
C23H25N3O11

M.W.:
519.46

Type:
---

AlogP:
-3.30

Polar Surface Area:
226.79

HBA:
12

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA5283961

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(6,7-dideoxy-7-(3-methylphenyShow More⌵

Mol. Formula:
C23H27N3O9

M.W.:
489.48

Type:
---

AlogP:
-2.69

Polar Surface Area:
189.49

HBA:
11

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5291217

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(N-benzenesulfonyl-4-aminoShow More⌵

Mol. Formula:
C28H30N4O11S

M.W.:
630.63

Type:
---

AlogP:
-2.20

Polar Surface Area:
235.66

HBA:
13

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.13

DETAILS

ALA5290020

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(3-aminophenyl)-6,7-dideoxShow More⌵

Mol. Formula:
C22H26N4O9

M.W.:
490.47

Type:
---

AlogP:
-3.42

Polar Surface Area:
215.51

HBA:
12

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.16

DETAILS

ALA5289885

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(4-biphenyl)-6,7-dideoxy-aShow More⌵

Mol. Formula:
C28H29N3O9

M.W.:
551.55

Type:
---

AlogP:
-1.33

Polar Surface Area:
189.49

HBA:
11

HBD:
6

#RO5 Violations:
3

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.20

DETAILS

ALA5288794

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(6,7-dideoxy-7-(4-methylphenyShow More⌵

Mol. Formula:
C23H27N3O9

M.W.:
489.48

Type:
---

AlogP:
-2.69

Polar Surface Area:
189.49

HBA:
11

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5277590

Name:
methyl (2R,3R,4R)-2-((R)-2-amino-1-((2S,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropShow More⌵

Mol. Formula:
C18H23N3O12

M.W.:
473.39

Type:
---

AlogP:
-4.18

Polar Surface Area:
221.86

HBA:
13

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5277496

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(3-biphenyl)-6,7-dideoxy-aShow More⌵

Mol. Formula:
C28H29N3O9

M.W.:
551.55

Type:
---

AlogP:
-1.33

Polar Surface Area:
189.49

HBA:
11

HBD:
6

#RO5 Violations:
3

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.20

DETAILS

ALA5266213

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(3-carboxyphenyl)-6,7-dideShow More⌵

Mol. Formula:
C23H25N3O11

M.W.:
519.46

Type:
---

AlogP:
-3.30

Polar Surface Area:
226.79

HBA:
12

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA5265879

Name:
5-O-(5-Amino-5-decoxy-beta-D-ribofuranosyl)-1-(7-(4-carboxyphenyl)-6,7-dideShow More⌵

Mol. Formula:
C23H25N3O11

M.W.:
519.46

Type:
---

AlogP:
-3.30

Polar Surface Area:
226.79

HBA:
12

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA5220850

Name:
5'-O-[4-Deoxy-N-[(3S)-hexahydro-2-oxo-1H-azepin-3-yl]-beta-L-erythro-hex-4-Show More⌵

Mol. Formula:
C21H28N4O11

M.W.:
512.47

11 activity values

10 unique targets

Type:
---

AlogP:
-4.08

Polar Surface Area:
221.67

HBA:
12

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.19

DETAILS