Compounds

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ALA2409633
Name:
3-[(1-Methyl-2(S)-pyrrolidinyl)methoxy]-5-[(1R,2S)-2-(2-methoxyethyl)cyclopShow More⌵
Mol. Formula:
C19H27F3N2O4
M.W.:
404.43
7 activity values
6 unique targets
Type:
Small molecule
AlogP:
2.69
Polar Surface Area:
34.59
HBA:
4
HBD:
---
#RO5 Violations:
---
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.77
DETAILS
CLOSE
ALA2409630
Name:
3-[(1-Methyl-2(R)-pyrrolidinyl)methoxy]-5-[(1S,2R)-2-(2-methoxyethyl)cyclopShow More⌵
Mol. Formula:
C19H27F3N2O4
M.W.:
404.43
7 activity values
6 unique targets
Type:
Small molecule
AlogP:
2.69
Polar Surface Area:
34.59
HBA:
4
HBD:
---
#RO5 Violations:
---
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.77
DETAILS
CLOSE
ALA2409623
Name:
3-[(2(S)-Azetidinyl)methoxy]-5-[(1R,2S)-2-(2-(morpholin-4-yl)ethyl)cycloproShow More⌵
Mol. Formula:
C20H28F3N3O4
M.W.:
431.46
7 activity values
6 unique targets
Type:
Small molecule
AlogP:
1.65
Polar Surface Area:
46.62
HBA:
5
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.83
DETAILS
CLOSE
ALA2409622
Name:
Isopropyl[2-[(1R,2S)-2-[5-[((S)-Azetidin-2-yl)methoxy]-pyridin-3-yl]cycloprShow More⌵
Mol. Formula:
C20H28F3N3O5
M.W.:
447.45
7 activity values
6 unique targets
Type:
Small molecule
AlogP:
2.45
Polar Surface Area:
72.48
HBA:
5
HBD:
2
#RO5 Violations:
---
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.76
DETAILS
CLOSE
ALA2409619
Name:
3-[(2(S)-Azetidinyl)methoxy]-5-[(1S,2R)-2-(2-(morpholin-4-yl)ethyl)cycloproShow More⌵
Mol. Formula:
C20H28F3N3O4
M.W.:
431.46
7 activity values
6 unique targets
Type:
Small molecule
AlogP:
1.65
Polar Surface Area:
46.62
HBA:
5
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.83
DETAILS
CLOSE
ALA2323567
Name:
(R)-5-(Hex-1-ynyl)-2-methyl-3-(pyrrolidin-2-ylmethoxy)Pyridine
Mol. Formula:
C17H24N2O
M.W.:
272.39
18 activity values
14 unique targets
Type:
Small molecule
AlogP:
3.06
Polar Surface Area:
34.15
HBA:
3
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.66
DETAILS
CLOSE
ALA2323565
Name:
(R)-3-(Azetidin-2-ylmethoxy)-5-(hex-1-ynyl)-2-methylpyridine
Mol. Formula:
C16H22N2O
M.W.:
258.36
18 activity values
14 unique targets
Type:
Small molecule
AlogP:
2.67
Polar Surface Area:
34.15
HBA:
3
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.65
DETAILS
CLOSE