Compounds

ALA5272364

Name:
4-(1-(2-Aminopyrimidin-4-yl)-2,3-dihydro-1H-pyrrolo[3,2-c]-pyridin-6-yl)-2-Show More⌵

Mol. Formula:
C16H17N5O

M.W.:
295.35

Type:
---

AlogP:
1.27

Polar Surface Area:
88.16

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5271137

Name:
(S)-4-(1-(2-Aminopyrimidin-4-yl)-3-(1-methylpiperidin-3-yl)-1H-pyrrolo[3,2-Show More⌵

Mol. Formula:
C22H26N6O

M.W.:
390.49

Type:
---

AlogP:
2.33

Polar Surface Area:
93.09

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA5269486

Name:
2-(3-(1-(2-Aminopyrimidin-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl)-cyclobutyl)pShow More⌵

Mol. Formula:
C18H21N5O

M.W.:
323.40

Type:
---

AlogP:
2.66

Polar Surface Area:
89.85

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5268795

Name:
4-(1-(2-Aminopyrimidin-4-yl)-3-cyclopropyl-1H-pyrrolo[3,2-d]pyridin-6-yl)-2Show More⌵

Mol. Formula:
C19H19N5O

M.W.:
333.40

Type:
---

AlogP:
2.40

Polar Surface Area:
89.85

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5268080

Name:
(S)-1-(1-(2-Amino-5-methoxypyrimidin-4-yl)-1H-pyrrolo[3,2-c]-pyridin-6-yl)-Show More⌵

Mol. Formula:
C18H19N5O2

M.W.:
337.38

Type:
---

AlogP:
1.92

Polar Surface Area:
99.08

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5282564

Name:
rac-trans-2-(2-(1-(2-Aminopyrimidin-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl)cycShow More⌵

Mol. Formula:
C17H19N5O

M.W.:
309.37

Type:
---

AlogP:
2.27

Polar Surface Area:
89.85

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5282072

Name:
4-(1-(2-Aminopyrimidin-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl)-2-methylbut-3-yShow More⌵

Mol. Formula:
C16H15N5O

M.W.:
293.33

Type:
---

AlogP:
1.52

Polar Surface Area:
89.85

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA5281273

Name:
2-(3-(1-(2-Aminopyrimidin-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl)-bicyclo(1.1.Show More⌵

Mol. Formula:
C19H21N5O

M.W.:
335.41

Type:
---

AlogP:
2.59

Polar Surface Area:
89.85

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5280803

Name:
4-(1-(2-Aminopyrimidin-4-yl)-5-methoxy-1H-indol-6-yl)-2-methylbut-3-yn-2-ol

Mol. Formula:
C18H18N4O2

M.W.:
322.37

Type:
---

AlogP:
2.13

Polar Surface Area:
86.19

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5280210

Name:
(S)-1-(1-(2-Amino-6-methoxypyrimidin-4-yl)-1H-pyrrolo[3,2-c]-pyridin-6-yl)-Show More⌵

Mol. Formula:
C18H19N5O2

M.W.:
337.38

Type:
---

AlogP:
1.92

Polar Surface Area:
99.08

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5279863

Name:
4-(1-(2-Aminopyrimidin-4-yl)-3-(tetrohydro-2H-pyran-4-yl)-1H-pyrrolo[3,2-c]Show More⌵

Mol. Formula:
C21H23N5O2

M.W.:
377.45

Type:
---

AlogP:
2.41

Polar Surface Area:
99.08

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA5279159

Name:
4-(3-(2-aminopyrimidin-4-yl)-1H-indazol-5-yl)-2-methylbut-3-yn-2-ol

Mol. Formula:
C16H15N5O

M.W.:
293.33

Type:
---

AlogP:
1.72

Polar Surface Area:
100.71

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5278744

Name:
4-(1-(2-Aminopyrimidin-4-yl)-1H-pyrazolo[4,3-c]pyridin-6-yl)-2-methylbut-3-Show More⌵

Mol. Formula:
C15H14N6O

M.W.:
294.32

Type:
---

AlogP:
0.92

Polar Surface Area:
102.74

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA5275588

Name:
4-(3-(2-aminopyrimidin-4-yl)-1-methyl-1H-pyrazolo[3,4-c]pyridin-5-yl)-2-metShow More⌵

Mol. Formula:
C16H16N6O

M.W.:
308.35

Type:
---

AlogP:
1.13

Polar Surface Area:
102.74

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA5274528

Name:
4-(1-(2-Aminopyrimidin-4-yl)-5-fluoro-1H-indol-6-yl)-2-methylbut-3-yn-2-ol

Mol. Formula:
C17H15FN4O

M.W.:
310.33

Type:
---

AlogP:
2.26

Polar Surface Area:
76.96

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA5274162

Name:
(S)-1-(1-(6-Aminopyrimidin-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl)-3-methylpenShow More⌵

Mol. Formula:
C17H17N5O

M.W.:
307.36

Type:
---

AlogP:
1.91

Polar Surface Area:
89.85

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5273263

Name:
(S)-1-(1-(2-Aminopyrimidin-4-yl)-1H-pyrozolo[4,3-c]pyridin-6-yl)-3-methylpeShow More⌵

Mol. Formula:
C16H16N6O

M.W.:
308.35

Type:
---

AlogP:
1.31

Polar Surface Area:
102.74

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5272862

Name:
(E)-4-(1-(2-Aminopyrimidin-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl)-2-methylbutShow More⌵

Mol. Formula:
C16H17N5O

M.W.:
295.35

Type:
---

AlogP:
2.18

Polar Surface Area:
89.85

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5287032

Name:
4-(1-(2-Aminopyrimidin-4-yl)-1H-pyrozolo[4,3-c]pyridin-6-yl)-phenol

Mol. Formula:
C16H12N6O

M.W.:
304.31

Type:
---

AlogP:
2.17

Polar Surface Area:
102.74

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5286028

Name:
4-(1-(2-Aminopyrimidin-4-yl)-1H-pyrazolo[4,3-c]pyridin-6-yl)-2-methylbutan-Show More⌵

Mol. Formula:
C15H18N6O

M.W.:
298.35

Type:
---

AlogP:
1.50

Polar Surface Area:
102.74

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.76

DETAILS