Compounds

ALA5267349

Name:
5-(2-(2-(5-Ethoxyquinoline-8-sulfonamido)phenyl)ethynyl)-4-methoxypyridine-Show More⌵

Mol. Formula:
C26H21N3O6S

M.W.:
503.54

Type:
---

AlogP:
3.94

Polar Surface Area:
127.71

HBA:
7

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA5267318

Name:
(R)-2-((1-(2-(azetidin-1-yl)phenyl)-5-(3-cyclopropoxyphenyl)-1H-pyrazol-3-yShow More⌵

Mol. Formula:
C27H31N3O4

M.W.:
461.56

Type:
---

AlogP:
5.06

Polar Surface Area:
76.82

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5266771

Name:
4-(2-(3-Methoxy-benzenesulfonylamino)-phenylethynyl)benzoic Acid

Mol. Formula:
C22H17NO5S

M.W.:
407.45

Type:
---

AlogP:
3.59

Polar Surface Area:
92.70

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5266150

Name:
4-(2-(4-Methoxy-2,3-dimethyl-benzenesulfonylamino)-phenylethynyl)benzoic AcShow More⌵

Mol. Formula:
C24H21NO5S

M.W.:
435.50

Type:
---

AlogP:
4.21

Polar Surface Area:
92.70

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5266104

Name:
5-(2-(2-Methyl-quinoline-8-sulfonylamino)-phenylethynyl))-pyridine-2-carboxShow More⌵

Mol. Formula:
C24H17N3O4S

M.W.:
443.48

Type:
---

AlogP:
3.84

Polar Surface Area:
109.25

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5265956

Name:
3-Methyl-5-(2-(7-methyl-quinoline-8-sulfonylamino)-phenylethynyl)-pyridine-Show More⌵

Mol. Formula:
C25H19N3O4S

M.W.:
457.51

Type:
---

AlogP:
4.15

Polar Surface Area:
109.25

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5282350

Name:
3-(2-(2-(Naphthalene-2-sulfonamido)phenyl)ethynyl)benzoic Acid

Mol. Formula:
C25H17NO4S

M.W.:
427.48

Type:
---

AlogP:
4.74

Polar Surface Area:
83.47

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5282166

Name:
6-(2-(2-(5-Methoxyquinoline-8-sulfonamido)phenyl)ethynyl)pyridazine-3-carboShow More⌵

Mol. Formula:
C23H16N4O5S

M.W.:
460.47

Type:
---

AlogP:
2.93

Polar Surface Area:
131.37

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5281759

Name:
2-(5-(2-(3,4-Dichloro-benzoyiamino)-phenyl)-pentyl)benzoic Acid

Mol. Formula:
C25H23Cl2NO3

M.W.:
456.37

Type:
---

AlogP:
6.90

Polar Surface Area:
66.40

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.34

DETAILS

ALA5281536

Name:
2-(2-(2-(Naphthalene-1-sulfonylamino)-phenyl)-ethyl)benzoic Acid

Mol. Formula:
C25H21NO4S

M.W.:
431.51

Type:
---

AlogP:
5.12

Polar Surface Area:
83.47

HBA:
3

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5281492

Name:
5-(2-(2-(5-Ethoxyquinoline-8-sulfonamido)phenyl)ethynyl)-3-(methylamino)priShow More⌵

Mol. Formula:
C26H22N4O5S

M.W.:
502.55

Type:
---

AlogP:
3.97

Polar Surface Area:
130.51

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.32

DETAILS

ALA5281466

Name:
4-(2-(2,5-Dichloro-benzenesulfonylamino)-phenylethynyl)benzoic Acid

Mol. Formula:
C21H13Cl2NO4S

M.W.:
446.31

Type:
---

AlogP:
4.89

Polar Surface Area:
83.47

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA5281178

Name:
4-((E)-2-(2-(Naphthalene-2-sulfonamido)phenyl)ethenyl)benzoic Acid

Mol. Formula:
C25H19NO4S

M.W.:
429.50

Type:
---

AlogP:
5.51

Polar Surface Area:
83.47

HBA:
3

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5280923

Name:
5-[2-(2-{4-[2-(2-Phenoxyethoxy)ethoxy]quinoline-8-sulfonamido}phenyl)ethynyShow More⌵

Mol. Formula:
C33H27N3O7S

M.W.:
609.66

Type:
---

AlogP:
5.00

Polar Surface Area:
136.94

HBA:
8

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.15

DETAILS

ALA5280833

Name:
4-(2-(4-Methoxy-benzenesulfonylamino)-phenylethynyl)-benzoic Acid

Mol. Formula:
C22H17NO5S

M.W.:
407.45

Type:
---

AlogP:
3.59

Polar Surface Area:
92.70

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5280358

Name:
2-Fluoro-4-(2-(naphthalene-1-sulfonylamino)-phenylethynyl)benzoic Acid

Mol. Formula:
C25H16FNO4S

M.W.:
445.47

Type:
---

AlogP:
4.88

Polar Surface Area:
83.47

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5280269

Name:
4-(2-(2-(naphthalene-2-sulfonamido)phenyl)ethynyl)benzoic Acid

Mol. Formula:
C25H17NO4S

M.W.:
427.48

Type:
---

AlogP:
4.74

Polar Surface Area:
83.47

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5280178

Name:
2-(5-(2-((Naphthalene-2-carbonyl)-amino)-phenyl)-pentyl)benzoic Acid

Mol. Formula:
C29H27NO3

M.W.:
437.54

Type:
---

AlogP:
6.75

Polar Surface Area:
66.40

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA5280173

Name:
3-((Z)-2-(2-(Naphthalene-2-sulfonamido)phenyl)ethenyl)benzoic Acid

Mol. Formula:
C25H19NO4S

M.W.:
429.50

Type:
---

AlogP:
5.51

Polar Surface Area:
83.47

HBA:
3

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5279664

Name:
3-(2-(2-(4-Fluoro-benzenesulfonylamino)-phenyl)-ethyl)benzoic Acid

Mol. Formula:
C21H18FNO4S

M.W.:
399.44

Type:
---

AlogP:
4.11

Polar Surface Area:
83.47

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.63

DETAILS