Compounds

Type:
---

AlogP:
1.99

Polar Surface Area:
105.48

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5197478

Name:
(2-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)-7,8-dihydro-1,6-naphShow More⌵

Mol. Formula:
C24H24FN3O4

M.W.:
437.47

Type:
---

AlogP:
3.83

Polar Surface Area:
77.69

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5196475

Name:
6-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)-3,4-dihydro-2,7-naphtShow More⌵

Mol. Formula:
C19H16FN3O3

M.W.:
353.35

6 activity values

3 unique targets

Type:
---

AlogP:
3.05

Polar Surface Area:
77.25

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5202280

Name:
1-(2-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)-7,8-dihydro-1,6-naShow More⌵

Mol. Formula:
C21H20FN3O3

M.W.:
381.41

Type:
---

AlogP:
3.67

Polar Surface Area:
68.46

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5200752

Name:
1-(2-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)-7,8-dihydro-1,6-naShow More⌵

Mol. Formula:
C23H24FN3O5S

M.W.:
473.53

Type:
---

AlogP:
3.08

Polar Surface Area:
102.60

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA5200620

Name:
(2-((1-(4-fluorophenyl)-4-methyl-1H-1,2,3-triazol-5-yl)methoxy)-7,8-dihydroShow More⌵

Mol. Formula:
C23H24FN5O3

M.W.:
437.48

Type:
---

AlogP:
2.75

Polar Surface Area:
82.37

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5200451

Name:
(2-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)-7,8-dihydro-1,6-naphShow More⌵

Mol. Formula:
C23H19FN4O4

M.W.:
434.43

Type:
---

AlogP:
3.95

Polar Surface Area:
94.49

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA5199140

Name:
1-(2-((1-(4-fluorophenyl)-4-methyl-1H-1,2,3-triazol-5-yl)methoxy)-7,8-dihydShow More⌵

Mol. Formula:
C21H22FN5O2

M.W.:
395.44

Type:
---

AlogP:
2.98

Polar Surface Area:
73.14

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA5208332

Name:
(2-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)-7,8-dihydro-1,6-naphShow More⌵

Mol. Formula:
C25H27FN4O3

M.W.:
450.51

Type:
---

AlogP:
4.73

Polar Surface Area:
71.70

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5208183

Name:
2-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)-6-isopropyl-7,8-dihydShow More⌵

Mol. Formula:
C22H22FN3O3

M.W.:
395.43

Type:
---

AlogP:
4.17

Polar Surface Area:
68.46

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA5207799

Name:
2-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)-6-methyl-7,8-dihydro-Show More⌵

Mol. Formula:
C20H18FN3O3

M.W.:
367.38

Type:
---

AlogP:
3.39

Polar Surface Area:
68.46

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5207798

Name:
1-(2-((1-(4-fluorophenyl)-4-methyl-1H-1,2,3-triazol-5-yl)methoxy)-7,8-dihydShow More⌵

Mol. Formula:
C20H20FN5O2

M.W.:
381.41

20 activity values

Type:
---

AlogP:
2.59

Polar Surface Area:
73.14

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5206831

Name:
4-(2-((1-(4-fluorophenyl)-4-methyl-1H-1,2,3-triazol-5-yl)methoxy)-5,6,7,8-tShow More⌵

Mol. Formula:
C24H25FN6O3

M.W.:
464.50

Type:
---

AlogP:
2.05

Polar Surface Area:
93.45

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5195083

Name:
2-((1-(4-fluorophenyl)-4-methyl-1H-1,2,3-triazol-5-yl)methoxy)-6-(2-(methylShow More⌵

Mol. Formula:
C21H22FN5O4S

M.W.:
459.50

Type:
---

AlogP:
1.73

Polar Surface Area:
107.28

HBA:
8

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5193778

Name:
(2-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)-7,8-dihydro-1,6-naphShow More⌵

Mol. Formula:
C25H26FN3O4

M.W.:
451.50

Type:
---

AlogP:
4.07

Polar Surface Area:
77.69

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA5193523

Name:
6-cyclobutanecarbonyl-2-{[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoShow More⌵

Mol. Formula:
C24H24FN3O3

M.W.:
421.47

Type:
---

AlogP:
4.45

Polar Surface Area:
68.46

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5192467

Name:
(2-((1-(4-fluorophenyl)-4-methyl-1H-1,2,3-triazol-5-yl)methoxy)-7,8-dihydroShow More⌵

Mol. Formula:
C23H24FN5O3

M.W.:
437.48

Type:
---

AlogP:
2.61

Polar Surface Area:
82.37

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5189787

Name:
2-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)-6-(2-(methylsulfonyl)Show More⌵

Mol. Formula:
C22H22FN3O5S

M.W.:
459.50

Type:
---

AlogP:
2.81

Polar Surface Area:
102.60

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5189320

Name:
6-cyclopropanecarbonyl-2-{[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methShow More⌵

Mol. Formula:
C23H22FN3O3

M.W.:
407.45

Type:
---

AlogP:
4.06

Polar Surface Area:
68.46

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.64

DETAILS

ALA5185502

Name:
2-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)-7,8-dihydro-1,6-naphtShow More⌵

Mol. Formula:
C19H16FN3O3

M.W.:
353.35