Compounds

Type:
---

AlogP:
2.85

Polar Surface Area:
46.17

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
Y

QED Weighted:
0.93

DETAILS

ALA5179120

Name:
N-(adamantan-1-yl)tetrahydrothiophene-2-sulfonamide

Mol. Formula:
C14H23NO2S2

M.W.:
301.48

2 activity values

Type:
---

AlogP:
2.73

Polar Surface Area:
46.17

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.87

DETAILS

ALA5094750

Name:
4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)-N-(4-fluorophenyl)thiazol-Show More⌵

Mol. Formula:
C19H14F2N4S

M.W.:
368.41

Type:
Unknown

AlogP:
5.33

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5094216

Name:
N-(2,3-difluorophenyl)-4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)thiaShow More⌵

Mol. Formula:
C19H13F3N4S

M.W.:
386.40

Type:
Unknown

AlogP:
5.47

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5093495

Name:
4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)-N-(2,4,5-tribromophenyl)thShow More⌵

Mol. Formula:
C19H12Br3FN4S

M.W.:
587.11

Type:
Unknown

AlogP:
7.47

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA5093237

Name:
N-cyclohexyl-4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)thiazol-2-aminShow More⌵

Mol. Formula:
C19H21FN4S

M.W.:
356.47

Type:
Unknown

AlogP:
5.19

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5093045

Name:
N-benzyl-4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)thiazol-2-amine

Mol. Formula:
C20H17FN4S

M.W.:
364.45

Type:
Unknown

AlogP:
5.06

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5092649

Name:
4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)-N-(2,4,5-trimethylphenyl)tShow More⌵

Mol. Formula:
C22H21FN4S

M.W.:
392.50

Type:
Unknown

AlogP:
6.11

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5092520

Name:
4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)-N-(2,4,5-trifluorophenyl)tShow More⌵

Mol. Formula:
C19H12F4N4S

M.W.:
404.39

Type:
Unknown

AlogP:
5.60

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA5091778

Name:
N-(5-fluoro-2,4-dimethylphenyl)-4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phShow More⌵

Mol. Formula:
C21H18F2N4S

M.W.:
396.47

Type:
Unknown

AlogP:
5.94

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5090878

Name:
N-(3,4-difluorophenyl)-4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)thiaShow More⌵

Mol. Formula:
C19H13F3N4S

M.W.:
386.40

Type:
Unknown

AlogP:
5.47

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5090822

Name:
N-(2,4-difluorophenyl)-4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)thiaShow More⌵

Mol. Formula:
C19H13F3N4S

M.W.:
386.40

Type:
Unknown

AlogP:
5.47

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5090050

Name:
4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)-N-(2-fluoro-4-methylphenylShow More⌵

Mol. Formula:
C20H16F2N4S

M.W.:
382.44

Type:
Unknown

AlogP:
5.63

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5090037

Name:
N-(2,4-dichlorophenyl)-4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)thiaShow More⌵

Mol. Formula:
C19H13Cl2FN4S

M.W.:
419.31

Type:
Unknown

AlogP:
6.49

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA5089571

Name:
4-(4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)thiazol-2-ylamino)phenol

Mol. Formula:
C19H15FN4OS

M.W.:
366.42

Type:
Unknown

AlogP:
4.89

Polar Surface Area:
62.97

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5089471

Name:
4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)-N-(2,4,6-trifluorophenyl)tShow More⌵

Mol. Formula:
C19H12F4N4S

M.W.:
404.39

Type:
Unknown

AlogP:
5.60

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5089369

Name:
N-(2-fluoro-4,5-dimethylphenyl)-4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phShow More⌵

Mol. Formula:
C21H18F2N4S

M.W.:
396.47

Type:
Unknown

AlogP:
5.94

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5089225

Name:
N-(2,6-difluorophenyl)-4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)thiaShow More⌵

Mol. Formula:
C19H13F3N4S

M.W.:
386.40

Type:
Unknown

AlogP:
5.47

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5086975

Name:
4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)-N-(2-fluorophenyl)thiazol-Show More⌵

Mol. Formula:
C19H14F2N4S

M.W.:
368.41

Type:
Unknown

AlogP:
5.33

Polar Surface Area:
42.74

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5085862

Name:
4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)-N-(2-fluoro-5-methylphenylShow More⌵

Mol. Formula:
C20H16F2N4S

M.W.:
382.44