Compounds

Type:
Unknown

AlogP:
4.90

Polar Surface Area:
129.57

HBA:
10

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA5094319

Name:
7-(5-methoxy-2-(5-(piperazin-1-yl)pyridin-2-ylamino)pyrimidin-4-yl)-N,N-dimShow More⌵

Mol. Formula:
C24H27N9O

M.W.:
457.54

Type:
Unknown

AlogP:
2.71

Polar Surface Area:
104.22

HBA:
10

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5094031

Name:
Tert-butyl 4-(6-(4-(3-(dimethylamino)quinoxalin-6-yl)pyrimidin-2-ylamino)pyShow More⌵

Mol. Formula:
C28H33N9O2

M.W.:
527.63

Type:
Unknown

AlogP:
4.35

Polar Surface Area:
112.50

HBA:
10

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5094024

Name:
Tert-butyl 4-(6-(4-(2,3-dimethylquinoxalin-6-yl)-5-fluoropyrimidin-2-ylaminShow More⌵

Mol. Formula:
C28H31FN8O2

M.W.:
530.61

Type:
Unknown

AlogP:
5.04

Polar Surface Area:
109.26

HBA:
9

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA5093557

Name:
5-fluoro-N-(5-((4-(methylsulfonyl)piperazin-1-yl)methyl)pyridin-2-yl)-4-(quShow More⌵

Mol. Formula:
C23H23FN8O2S

M.W.:
494.56

Type:
Unknown

AlogP:
2.44

Polar Surface Area:
117.10

HBA:
9

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5093550

Name:
(6-(4-(2,3-dimethylquinoxalin-6-yl)-5-fluoropyrimidin-2-ylamino)pyridin-3-yShow More⌵

Mol. Formula:
C25H25FN8O

M.W.:
472.53

Type:
Unknown

AlogP:
3.37

Polar Surface Area:
100.03

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5093528

Name:
N,N-diethyl-7-(5-fluoro-2-((5-((4-isopropylpiperazin-1-yl)methyl)pyridin-2-Show More⌵

Mol. Formula:
C29H36FN9

M.W.:
529.67

Type:
Unknown

AlogP:
4.74

Polar Surface Area:
86.20

HBA:
9

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.33

DETAILS

ALA5092768

Name:
Tert-butyl 4-(6-(4-(3-(dimethylamino)quinoxalin-6-yl)-5-fluoropyrimidin-2-yShow More⌵

Mol. Formula:
C28H32FN9O2

M.W.:
545.62

Type:
Unknown

AlogP:
4.49

Polar Surface Area:
112.50

HBA:
10

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA5092066

Name:
Tert-butyl 4-(6-(4-(2,3-dimethylquinoxalin-6-yl)-5-fluoropyrimidin-2-ylaminShow More⌵

Mol. Formula:
C29H31FN8O3

M.W.:
558.62

Type:
Unknown

AlogP:
4.67

Polar Surface Area:
126.33

HBA:
9

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA5091949

Name:
(6-(4-(3-(dimethylamino)quinoxalin-6-yl)pyrimidin-2-ylamino)pyridin-3-yl)(4Show More⌵

Mol. Formula:
C27H31N9O

M.W.:
497.61

Type:
Unknown

AlogP:
3.46

Polar Surface Area:
103.27

HBA:
9

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5091299

Name:
(6-(4-(3-(dimethylamino)quinoxalin-6-yl)-5-methoxypyrimidin-2-ylamino)pyridShow More⌵

Mol. Formula:
C25H27N9O2

M.W.:
485.55

Type:
Unknown

AlogP:
2.35

Polar Surface Area:
121.29

HBA:
10

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5090931

Name:
4-(2,3-dimethylquinoxalin-6-yl)-5-fluoro-N-(5-(piperazin-1-yl)pyridin-2-yl)Show More⌵

Mol. Formula:
C23H23FN8

M.W.:
430.49

Type:
Unknown

AlogP:
3.39

Polar Surface Area:
91.75

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5090631

Name:
Tert-butyl 4-(6-(5-fluoro-4-(3-morpholinoquinoxalin-6-yl)pyrimidin-2-ylaminShow More⌵

Mol. Formula:
C31H34FN9O4

M.W.:
615.67

Type:
Unknown

AlogP:
3.89

Polar Surface Area:
138.80

HBA:
11

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.35

DETAILS

ALA5089915

Name:
7-(5-fluoro-2-(5-(piperazin-1-yl)pyridin-2-ylamino)pyrimidin-4-yl)-N,N-dimeShow More⌵

Mol. Formula:
C23H24FN9

M.W.:
445.51

Type:
Unknown

AlogP:
2.84

Polar Surface Area:
94.99

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5089681

Name:
Tert-butyl 4-(6-(5-fluoro-4-(3-morpholinoquinoxalin-6-yl)pyrimidin-2-ylaminShow More⌵

Mol. Formula:
C30H34FN9O3

M.W.:
587.66

Type:
Unknown

AlogP:
4.26

Polar Surface Area:
121.73

HBA:
11

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA5089214

Name:
N,N-diethyl-7-(5-fluoro-2-(5-(4-methylpiperazin-1-yl)pyridin-2-ylamino)pyriShow More⌵

Mol. Formula:
C26H30FN9

M.W.:
487.59

Type:
Unknown

AlogP:
3.96

Polar Surface Area:
86.20

HBA:
9

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5088870

Name:
4-(2,3-dimethylquinoxalin-6-yl)-N-(5-((4-ethylpiperazin-1-yl)methyl)pyridinShow More⌵

Mol. Formula:
C26H29FN8

M.W.:
472.57

Type:
Unknown

AlogP:
4.12

Polar Surface Area:
82.96

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5088816

Name:
(6-(5-fluoro-4-(quinoxalin-6-yl)pyrimidin-2-ylamino)pyridin-3-yl)(piperazinShow More⌵

Mol. Formula:
C22H19FN8O

M.W.:
430.45

Type:
Unknown

AlogP:
2.41

Polar Surface Area:
108.82

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5088191

Name:
Tert-butyl 4-(6-(5-fluoro-4-(quinoxalin-6-yl)pyrimidin-2-ylamino)pyridin-3-Show More⌵

Mol. Formula:
C26H27FN8O2

M.W.:
502.55

Type:
Unknown

AlogP:
4.42

Polar Surface Area:
109.26

HBA:
9

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5087684

Name:
Tert-butyl 4-(6-(4-(3-(diethylamino)quinoxalin-6-yl)-5-fluoropyrimidin-2-ylShow More⌵

Mol. Formula:
C30H36FN9O2

M.W.:
573.68