Compounds

ALA5271307

Name:
N-(6-benzylsulfanylpyridazin-3-yl)-4-propyl-thiadiazole-5-carboxamide

Mol. Formula:
C17H17N5OS2

M.W.:
371.49

Type:
---

AlogP:
3.83

Polar Surface Area:
80.66

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.64

DETAILS

ALA5270996

Name:
N-[5-[(2,5-dichlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]-4-ethyl-thShow More⌵

Mol. Formula:
C14H11Cl2N5OS3

M.W.:
432.38

Type:
---

AlogP:
4.80

Polar Surface Area:
80.66

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5270814

Name:
N-[5-(cyclopentylmethylsulfanyl)-1,3,4-thiadiazol-2-yl]-4-ethyl-thiadiazoleShow More⌵

Mol. Formula:
C13H17N5OS3

M.W.:
355.51

Type:
---

AlogP:
3.49

Polar Surface Area:
80.66

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5270566

Name:
2-chloro-N-[5-(cyclopentylmethylsulfanyl)-1,3,4-thiadiazol-2-yl]imidazo[1,2Show More⌵

Mol. Formula:
C16H16ClN5OS2

M.W.:
393.93

Type:
---

AlogP:
4.37

Polar Surface Area:
72.18

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5269505

Name:
N-[5-[(3-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]-4-ethyl-thiadiShow More⌵

Mol. Formula:
C14H12ClN5OS3

M.W.:
397.94

Type:
---

AlogP:
4.15

Polar Surface Area:
80.66

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5268632

Name:
4-ethyl-N-[5-(3-thienylmethylsulfanyl)-1,3,4-thiadiazol-2-yl]thiadiazole-5-Show More⌵

Mol. Formula:
C12H11N5OS4

M.W.:
369.52

Type:
---

AlogP:
3.56

Polar Surface Area:
80.66

HBA:
9

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5280335

Name:
N-[5-[(3,5-dimethylphenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]-4-ethyl-thShow More⌵

Mol. Formula:
C16H17N5OS3

M.W.:
391.55

Type:
---

AlogP:
4.11

Polar Surface Area:
80.66

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5280182

Name:
4-ethyl-N-[5-(p-tolylmethylsulfanyl)-1,3,4-thiadiazol-2-yl]thiadiazole-5-caShow More⌵

Mol. Formula:
C15H15N5OS3

M.W.:
377.52

Type:
---

AlogP:
3.81

Polar Surface Area:
80.66

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA5279052

Name:
N-[5-[(3,4-dimethylphenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]-4-ethyl-thShow More⌵

Mol. Formula:
C16H17N5OS3

M.W.:
391.55

Type:
---

AlogP:
4.11

Polar Surface Area:
80.66

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5277742

Name:
N-[5-(benzylsulfanyl)-1,3,4-thiadiazol-2-yl]-4-ethyl-1,2,3-thiadiazole-5-caShow More⌵

Mol. Formula:
C14H13N5OS3

M.W.:
363.49

Type:
---

AlogP:
3.50

Polar Surface Area:
80.66

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5276858

Name:
N-[5-(benzylsulfanyl)-1,3,4-thiadiazol-2-yl]-4-methyl-1,2,3-thiadiazole-5-cShow More⌵

Mol. Formula:
C13H11N5OS3

M.W.:
349.47

Type:
---

AlogP:
3.24

Polar Surface Area:
80.66

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA5276527

Name:
4-ethyl-N-(5-{[(3-fluorophenyl)methyl]sulfanyl}-1,3,4-thiadiazol-2-yl)-1,2,Show More⌵

Mol. Formula:
C14H12FN5OS3

M.W.:
381.48

Type:
---

AlogP:
3.64

Polar Surface Area:
80.66

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA5275196

Name:
1-[(3-fluorophenyl)methyl]-N-(5-nitrothiazol-2-yl)-6-oxo-pyridazine-3-carboShow More⌵

Mol. Formula:
C15H10FN5O4S

M.W.:
375.34

Type:
---

AlogP:
2.05

Polar Surface Area:
120.02

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5274590

Name:
N-[5-(cyclopentylmethylsulfanyl)-1,3,4-thiadiazol-2-yl]-5-fluoro-1-methyl-iShow More⌵

Mol. Formula:
C18H19FN4OS2

M.W.:
390.51

Type:
---

AlogP:
4.70

Polar Surface Area:
59.81

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5274262

Name:
4-ethyl-N-[5-(2-pyridylmethylsulfanyl)-1,3,4-thiadiazol-2-yl]thiadiazole-5-Show More⌵

Mol. Formula:
C13H12N6OS3

M.W.:
364.48

Type:
---

AlogP:
2.89

Polar Surface Area:
93.55

HBA:
9

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA5274079

Name:
2,2,2-trichloro-N-[4-(2,4-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-ylShow More⌵

Mol. Formula:
C15H12Cl3N3O3S

M.W.:
420.71

Type:
---

AlogP:
3.86

Polar Surface Area:
71.53

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.75

DETAILS

ALA5273874

Name:
4-ethyl-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)thiadiazole-5-carboxamide

Mol. Formula:
C9H11N5OS3

M.W.:
301.42

Type:
---

AlogP:
2.32

Polar Surface Area:
80.66

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA5273292

Name:
N-[5-(benzylsulfanyl)-1,3,4-thiadiazol-2-yl]-4-(propan-2-yl)-1,2,3-thiadiazShow More⌵

Mol. Formula:
C15H15N5OS3

M.W.:
377.52

Type:
---

AlogP:
4.06

Polar Surface Area:
80.66

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA5273275

Name:
N-[5-(benzylsulfanyl)-1,3,4-thiadiazol-2-yl]-4-propyl-1,2,3-thiadiazole-5-cShow More⌵

Mol. Formula:
C15H15N5OS3

M.W.:
377.52

Type:
---

AlogP:
3.89

Polar Surface Area:
80.66

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5273158

Name:
4-ethyl-N-(5-phenylmethanesulfonyl-1,3,4-thiadiazol-2-yl)-1,2,3-thiadiazoleShow More⌵

Mol. Formula:
C14H13N5O3S3

M.W.:
395.49

Type:
---

AlogP:
2.18

Polar Surface Area:
114.80

HBA:
9

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.64

DETAILS