Compounds

Type:
Small molecule

AlogP:
3.36

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA2270591

Name:
6-Bromo-7-(2,2,2-trifluoro-ethyl)-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dionShow More⌵

Mol. Formula:
C13H6BrF3N2O2

M.W.:
359.10

Type:
Small molecule

AlogP:
3.16

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA2270590

Name:
6-Bromo-7-propoxy-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C14H11BrN2O3

M.W.:
335.16

Type:
Small molecule

AlogP:
2.59

Polar Surface Area:
60.67

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA2270589

Name:
6-Bromo-7-(2,2-dimethyl-propyl)-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C16H15BrN2O2

M.W.:
347.21

Type:
Small molecule

AlogP:
3.64

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA2270588

Name:
6-Bromo-7-isopropyl-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C14H11BrN2O2

M.W.:
319.16

Type:
Small molecule

AlogP:
2.86

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA2270587

Name:
6-Bromo-7-tert-butyl-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C15H13BrN2O2

M.W.:
333.19

Type:
Small molecule

AlogP:
3.25

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
---

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA2270586

Name:
6-Bromo-7-(1-ethyl-propyl)-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C16H15BrN2O2

M.W.:
347.21

Type:
Small molecule

AlogP:
3.64

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA2270362

Name:
6-Bromo-7-(1,1-dimethyl-propyl)-benzo[4,5]imidazo[1,2-a]pyridine-8,9-d ione

Mol. Formula:
C16H15BrN2O2

M.W.:
347.21

Type:
Small molecule

AlogP:
3.64

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA2270361

Name:
6-Bromo-7-cyclohexyl-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C17H15BrN2O2

M.W.:
359.22

Type:
Small molecule

AlogP:
3.79

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA2270360

Name:
6-Bromo-7-(1-propyl-butyl)-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C18H19BrN2O2

M.W.:
375.27

Type:
Small molecule

AlogP:
4.42

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA2270359

Name:
6-Bromo-7-heptyl-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C18H19BrN2O2

M.W.:
375.27

7 activity values

Type:
Small molecule

AlogP:
4.57

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA2270358

Name:
6-Bromo-7-isobutyl-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C15H13BrN2O2

M.W.:
333.19

Type:
Small molecule

AlogP:
3.25

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA2270357

Name:
6-Bromo-7-ethyl-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C13H9BrN2O2

M.W.:
305.13

Type:
Small molecule

AlogP:
2.62

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA2270356

Name:
6-Bromo-7-propyl-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C14H11BrN2O2

M.W.:
319.16

Type:
Small molecule

AlogP:
3.01

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA2270355

Name:
6-Bromo-7-methyl-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C12H7BrN2O2

M.W.:
291.10

Type:
Small molecule

AlogP:
2.23

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
---

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA2270354

Name:
6-Bromo-7-hexyl-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C17H17BrN2O2

M.W.:
361.24

Type:
Small molecule

AlogP:
4.18

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA2270353

Name:
6-Bromo-7-pentyl-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C16H15BrN2O2

M.W.:
347.21

Type:
Small molecule

AlogP:
3.79

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA2270352

Name:
6,7-Dibromo-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C11H4Br2N2O2

M.W.:
355.97

Type:
Small molecule

AlogP:
2.56

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
---

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA2270351

Name:
6-Bromo-7-butyl-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C15H13BrN2O2

M.W.:
333.19

Type:
Small molecule

AlogP:
3.40

Polar Surface Area:
51.44

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA2270350

Name:
6-Bromo-7-ethoxy-benzo[4,5]imidazo[1,2-a]pyridine-8,9-dione

Mol. Formula:
C13H9BrN2O3

M.W.:
321.13