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  1. ALA5205905

    Name:
    (5Z)-5-(4-Hydroxy-3-methoxy)benzylidene-2-[(4-(piperazin-1-yl)-phenyl)aminoShow More

    Mol. Formula:
    C21H23N5O3

    M.W.:
    393.45

    Type:
    ---

    AlogP:
    1.75

    Polar Surface Area:
    98.22

    HBA:
    7

    HBD:
    4

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.59

    DETAILS
  2. ALA5203292

    Name:
    (5Z)-5-(1,3-Benzodioxol-5-ylmethylene)-2-amino-3,5-dihydro-4H-imidazol-4-onShow More

    Mol. Formula:
    C11H9N3O3

    M.W.:
    231.21

    Type:
    ---

    AlogP:
    0.20

    Polar Surface Area:
    85.94

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    1

    Passes Ro3:
    N

    QED Weighted:
    0.68

    DETAILS
  3. ALA5202202

    Name:
    (5Z)-5-(1,3-Benzodioxol-5-ylmethylidene)-2-[(4-(piperazin-1-yl)-phenyl)aminShow More

    Mol. Formula:
    C21H21N5O3

    M.W.:
    391.43

    Type:
    ---

    AlogP:
    1.76

    Polar Surface Area:
    87.22

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.69

    DETAILS
  4. ALA5201763

    Name:
    (5Z)-5-(1,3-Benzodioxol-5-ylmethylidene)-2-(piperidin-1-yl)-3,5-dihydro-4H-Show More

    Mol. Formula:
    C16H17N3O3

    M.W.:
    299.33

    Type:
    ---

    AlogP:
    1.73

    Polar Surface Area:
    63.16

    HBA:
    5

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    1

    Passes Ro3:
    N

    QED Weighted:
    0.80

    DETAILS
  5. ALA5200677

    Name:
    (5Z)-5-(1,3-Benzodioxol-5-ylmethylidene)-2-methylamino-3,5-dihydro-4H-imidaShow More

    Mol. Formula:
    C12H11N3O3

    M.W.:
    245.24

    Type:
    ---

    AlogP:
    0.46

    Polar Surface Area:
    71.95

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    1

    Passes Ro3:
    N

    QED Weighted:
    0.71

    DETAILS
  6. ALA5199422

    Name:
    (5Z)-5-[(2,2-d2)-1,3-benzodioxol-5-ylmethylidene]-2-(phenylamino)-3,5-dihydShow More

    Mol. Formula:
    C17H13N3O3

    M.W.:
    309.32

    Type:
    ---

    AlogP:
    2.35

    Polar Surface Area:
    71.95

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.84

    DETAILS
  7. ALA5209464

    Name:
    (5Z)-5-(1,3-Benzodioxol-5-ylmethylidene)-2-[(4-pentyloxy-phenyl)amino]-3,5-Show More

    Mol. Formula:
    C22H23N3O4

    M.W.:
    393.44

    Type:
    ---

    AlogP:
    3.92

    Polar Surface Area:
    81.18

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.55

    DETAILS
  8. ALA5208980

    Name:
    (5Z)-5-(2,3-Dihydro-1-benzofuran-5-ylmethylidene)-2-phenylamino-3,5-dihydroShow More

    Mol. Formula:
    C18H15N3O2

    M.W.:
    305.34

    Type:
    ---

    AlogP:
    2.56

    Polar Surface Area:
    62.72

    HBA:
    4

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.84

    DETAILS
  9. ALA5207974

    Name:
    (5Z)-5-(3,4-dihydro-2H-chromen-6-ylmethylidene)-2-phenylamino-3,5-dihydro-4Show More

    Mol. Formula:
    C19H17N3O2

    M.W.:
    319.36

    Type:
    ---

    AlogP:
    2.95

    Polar Surface Area:
    62.72

    HBA:
    4

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.84

    DETAILS
  10. ALA5207630

    Name:
    (5Z)-5-(1,3-Benzodioxol-5-ylmethylidene)-2-(morpholin-4-yl)-3,5-dihydro-4H-Show More

    Mol. Formula:
    C15H15N3O4

    M.W.:
    301.30

    Type:
    ---

    AlogP:
    0.57

    Polar Surface Area:
    72.39

    HBA:
    6

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    1

    Passes Ro3:
    N

    QED Weighted:
    0.77

    DETAILS
  11. ALA5206744

    Name:
    (5Z)-5-(1,3-Benzodioxol-5-ylmethylidene)-2-(pyridin-2-ylamino)-3,5-dihydro-Show More

    Mol. Formula:
    C16H12N4O3

    M.W.:
    308.30

    Type:
    ---

    AlogP:
    1.75

    Polar Surface Area:
    84.84

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.83

    DETAILS
  12. ALA5206143

    Name:
    (5Z)-5-(1,3-Benzodioxol-5-ylmethylene)-2-(propylthio)-3,5-dihydro-4H-imidazShow More

    Mol. Formula:
    C14H14N2O3S

    M.W.:
    290.34

    Type:
    ---

    AlogP:
    2.39

    Polar Surface Area:
    59.92

    HBA:
    5

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.87

    DETAILS
  13. ALA5196066

    Name:
    (5Z)-5-(1,3-Benzodioxol-5-ylmethylidene)-2-[(3-fluoro-phenyl)amino]-3,5-dihShow More

    Mol. Formula:
    C17H12FN3O3

    M.W.:
    325.30

    Type:
    ---

    AlogP:
    2.49

    Polar Surface Area:
    71.95

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.83

    DETAILS
  14. ALA5195216

    Name:
    (5Z)-5-(1,4-Benzodioxin-6-ylmethylidene)-2-[(4-(4-methyl-piperazin-1-yl)-phShow More

    Mol. Formula:
    C23H23N5O3

    M.W.:
    417.47

    Type:
    ---

    AlogP:
    2.53

    Polar Surface Area:
    78.43

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.75

    DETAILS
  15. ALA5195122

    Name:
    (5Z)-5-(4-Hydroxy-3-methoxybenzylidene)-2-phenylamino-3,5-dihydro-4H-imidazShow More

    Mol. Formula:
    C17H15N3O3

    M.W.:
    309.32

    Type:
    ---

    AlogP:
    2.34

    Polar Surface Area:
    82.95

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.76

    DETAILS
  16. ALA5194689

    Name:
    (5Z)-5-(2,3-Dihydro-1,4-benzodioxin-6-ylmethylidene)-2-phenylamino-3,5-dihyShow More

    Mol. Formula:
    C18H15N3O3

    M.W.:
    321.34

    Type:
    ---

    AlogP:
    2.40

    Polar Surface Area:
    71.95

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.83

    DETAILS
  17. ALA5194491

    Name:
    (5Z)-5-(1,3-Benzodioxol-5-ylmethylene)-3-methyl-2-(propylthio)-3,5-dihydro-Show More

    Mol. Formula:
    C15H16N2O3S

    M.W.:
    304.37

    Type:
    ---

    AlogP:
    2.73

    Polar Surface Area:
    51.13

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.81

    DETAILS
  18. ALA5193677

    Name:
    (5Z)-5-(1,3-Benzodioxol-5-ylmethylidene)-2-(piperidin-4-ylamino)-3,5-dihydrShow More

    Mol. Formula:
    C16H18N4O3

    M.W.:
    314.35

    Type:
    ---

    AlogP:
    0.58

    Polar Surface Area:
    83.98

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.70

    DETAILS
  19. ALA5193292

    Name:
    (5Z)-5-(1,3-Benzodioxol-5-ylmethylidene)-2-{[(4-piperidin-1-yl)-phenyl]aminShow More

    Mol. Formula:
    C22H22N4O3

    M.W.:
    390.44

    Type:
    ---

    AlogP:
    3.34

    Polar Surface Area:
    75.19

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.79

    DETAILS
  20. ALA5191942

    Name:
    (5Z)-5-(3,4-Dihydroxybenzylidene)-2-phenylamino-3,5-dihydro-4H-imidazol-4-oShow More

    Mol. Formula:
    C16H13N3O3

    M.W.:
    295.30

    Type:
    ---

    AlogP:
    2.04

    Polar Surface Area:
    93.95

    HBA:
    5

    HBD:
    4

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.50

    DETAILS
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