Compounds

ALA5272591

Name:
(4-(2-(dimethylamino)-6-methylpyrimidin-4-yl)piperazin-1-yl)(o-tolyl)methanShow More⌵

Mol. Formula:
C19H25N5O

M.W.:
339.44

Type:
---

AlogP:
2.12

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.86

DETAILS

ALA5272210

Name:
1-(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)ethan-1-one

Mol. Formula:
C15H23N5O

M.W.:
289.38

Type:
---

AlogP:
1.05

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5271750

Name:
(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)(o-tolyl)methShow More⌵

Mol. Formula:
C21H27N5O

M.W.:
365.48

Type:
---

AlogP:
2.66

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.84

DETAILS

ALA5271587

Name:
(4-(2-(azetidin-1-yl)-6-methylpyrimidin-4-yl)piperazin-1-yl)(o-tolyl)methanShow More⌵

Mol. Formula:
C20H25N5O

M.W.:
351.45

Type:
---

AlogP:
2.27

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.85

DETAILS

ALA5270914

Name:
(4-(2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)(o-tolyl)methanone

Mol. Formula:
C20H25N5O

M.W.:
351.45

Type:
---

AlogP:
2.35

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.85

DETAILS

ALA5270898

Name:
(4-(tert-butyl)phenyl)(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperaShow More⌵

Mol. Formula:
C24H33N5O

M.W.:
407.56

Type:
---

AlogP:
3.65

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5268346

Name:
(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)(pyrazin-2-ylShow More⌵

Mol. Formula:
C18H23N7O

M.W.:
353.43

Type:
---

AlogP:
1.14

Polar Surface Area:
78.35

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5282146

Name:
(4-(tert-butyl)phenyl)(4-(2-(pyrrolidin-1-yl)-5,7-dihydrofuro[3,4-d]pyrimidShow More⌵

Mol. Formula:
C25H33N5O2

M.W.:
435.57

Type:
---

AlogP:
3.37

Polar Surface Area:
61.80

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5280450

Name:
(4-(2-(pyrrolidin-1-yl)quinazolin-4-yl)piperazin-1-yl)(o-tolyl)methanone

Mol. Formula:
C24H27N5O

M.W.:
401.51

Type:
---

AlogP:
3.50

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA5279401

Name:
(4-(2-(3,3-difluoropyrrolidin-1-yl)-6-methylpyrimidin-4-yl)piperazin-1-yl)(Show More⌵

Mol. Formula:
C21H25F2N5O

M.W.:
401.46

Type:
---

AlogP:
2.90

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5279069

Name:
(6-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)-2,6-diazaspiro[3.3]heptan-2Show More⌵

Mol. Formula:
C22H27N5O

M.W.:
377.49

Type:
---

AlogP:
2.66

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5278339

Name:
(4-(6-methyl-2-(piperidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)(o-tolyl)methaShow More⌵

Mol. Formula:
C22H29N5O

M.W.:
379.51

Type:
---

AlogP:
3.05

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5277174

Name:
(4-(tert-butyl)phenyl)(4-(2-(pyrrolidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pShow More⌵

Mol. Formula:
C26H35N5O

M.W.:
433.60

Type:
---

AlogP:
3.83

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5276663

Name:
(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)(p-tolyl)methShow More⌵

Mol. Formula:
C21H27N5O

M.W.:
365.48

Type:
---

AlogP:
2.66

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.84

DETAILS

ALA5276122

Name:
(2-chlorophenyl)(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-Show More⌵

Mol. Formula:
C20H24ClN5O

M.W.:
385.90

Type:
---

AlogP:
3.00

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5275563

Name:
(4-(6-methyl-2-morpholinopyrimidin-4-yl)piperazin-1-yl)(o-tolyl)methanone

Mol. Formula:
C21H27N5O2

M.W.:
381.48

Type:
---

AlogP:
1.89

Polar Surface Area:
61.80

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5272952

Name:
1-(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)-2-phenyletShow More⌵

Mol. Formula:
C21H27N5O

M.W.:
365.48

Type:
---

AlogP:
2.28

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.83

DETAILS

ALA5272738

Name:
(4-chlorophenyl)(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-Show More⌵

Mol. Formula:
C20H24ClN5O

M.W.:
385.90

Type:
---

AlogP:
3.00

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5286668

Name:
(4-(2-(pyrrolidin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)(oShow More⌵

Mol. Formula:
C21H25ClF3N5O

M.W.:
455.91

Type:
---

AlogP:
3.37

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5285901

Name:
(4-(tert-butyl)phenyl)(4-(2-(pyrrolidin-1-yl)-5,6,7,8-tetrahydroquinazolin-Show More⌵

Mol. Formula:
C27H37N5O

M.W.:
447.63

Type:
---

AlogP:
4.22

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.71

DETAILS