Compounds

ALA5267578

Name:
(4-(2-(pyrrolidin-1-yl)-1,5,7,7a-tetrahydrofuro[3,4-d]pyrimidin-4-yl)piperaShow More⌵

Mol. Formula:
C22H27N5O2

M.W.:
393.49

Type:
---

AlogP:
2.38

Polar Surface Area:
61.80

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA5266397

Name:
(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)(pyridin-4-ylShow More⌵

Mol. Formula:
C19H24N6O

M.W.:
352.44

Type:
---

AlogP:
1.74

Polar Surface Area:
65.46

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.84

DETAILS

ALA5266290

Name:
(4-(2-(azepan-1-yl)-6-methylpyrimidin-4-yl)piperazin-1-yl)(o-tolyl)methanonShow More⌵

Mol. Formula:
C23H31N5O

M.W.:
393.54

Type:
---

AlogP:
3.44

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA5265984

Name:
(4-(2-isopropyl-6-methylpyrimidin-4-yl)piperazin-1-yl)(o-tolyl)methanone

Mol. Formula:
C20H26N4O

M.W.:
338.46

Type:
---

AlogP:
3.18

Polar Surface Area:
49.33

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.86

DETAILS

ALA5282146

Name:
(4-(tert-butyl)phenyl)(4-(2-(pyrrolidin-1-yl)-5,7-dihydrofuro[3,4-d]pyrimidShow More⌵

Mol. Formula:
C25H33N5O2

M.W.:
435.57

Type:
---

AlogP:
3.37

Polar Surface Area:
61.80

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5280450

Name:
(4-(2-(pyrrolidin-1-yl)quinazolin-4-yl)piperazin-1-yl)(o-tolyl)methanone

Mol. Formula:
C24H27N5O

M.W.:
401.51

Type:
---

AlogP:
3.50

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA5279401

Name:
(4-(2-(3,3-difluoropyrrolidin-1-yl)-6-methylpyrimidin-4-yl)piperazin-1-yl)(Show More⌵

Mol. Formula:
C21H25F2N5O

M.W.:
401.46

Type:
---

AlogP:
2.90

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5279069

Name:
(6-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)-2,6-diazaspiro[3.3]heptan-2Show More⌵

Mol. Formula:
C22H27N5O

M.W.:
377.49

Type:
---

AlogP:
2.66

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5278339

Name:
(4-(6-methyl-2-(piperidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)(o-tolyl)methaShow More⌵

Mol. Formula:
C22H29N5O

M.W.:
379.51

Type:
---

AlogP:
3.05

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5277174

Name:
(4-(tert-butyl)phenyl)(4-(2-(pyrrolidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pShow More⌵

Mol. Formula:
C26H35N5O

M.W.:
433.60

Type:
---

AlogP:
3.83

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5276663

Name:
(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)(p-tolyl)methShow More⌵

Mol. Formula:
C21H27N5O

M.W.:
365.48

Type:
---

AlogP:
2.66

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.84

DETAILS

ALA5276122

Name:
(2-chlorophenyl)(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-Show More⌵

Mol. Formula:
C20H24ClN5O

M.W.:
385.90

Type:
---

AlogP:
3.00

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5275563

Name:
(4-(6-methyl-2-morpholinopyrimidin-4-yl)piperazin-1-yl)(o-tolyl)methanone

Mol. Formula:
C21H27N5O2

M.W.:
381.48

Type:
---

AlogP:
1.89

Polar Surface Area:
61.80

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5272952

Name:
1-(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)-2-phenyletShow More⌵

Mol. Formula:
C21H27N5O

M.W.:
365.48

Type:
---

AlogP:
2.28

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.83

DETAILS

ALA5291224

Name:
(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)(phenyl)methaShow More⌵

Mol. Formula:
C20H25N5O

M.W.:
351.45

Type:
---

AlogP:
2.35

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.85

DETAILS

ALA5290073

Name:
[1,1'-biphenyl]-4-yl(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperaziShow More⌵

Mol. Formula:
C26H29N5O

M.W.:
427.55

Type:
---

AlogP:
4.01

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5290054

Name:
(4-(5,6-dimethyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)(o-tolyl)Show More⌵

Mol. Formula:
C22H29N5O

M.W.:
379.51

Type:
---

AlogP:
2.96

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5289722

Name:
(4-(6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)-1,4-diazepan-1-yl)(o-tolyl)Show More⌵

Mol. Formula:
C22H29N5O

M.W.:
379.51

Type:
---

AlogP:
3.05

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5289693

Name:
(4-(6-(hydroxymethyl)-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)(o-tShow More⌵

Mol. Formula:
C21H27N5O2

M.W.:
381.48

Type:
---

AlogP:
1.84

Polar Surface Area:
72.80

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.87

DETAILS

ALA5289154

Name:
(4-(5-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)(o-tolyl)methShow More⌵

Mol. Formula:
C21H27N5O

M.W.:
365.48

Type:
---

AlogP:
2.66

Polar Surface Area:
52.57

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.84

DETAILS