Compounds

ALA4798179

Name:
1-(4-(4-chloro-2-oxopyridin-1(2H)-yl)phenyl)-N-ethyl-5-(trifluoromethyl)-1HShow More⌵

Mol. Formula:
C18H14ClF3N4O2

M.W.:
410.78

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.45

Polar Surface Area:
68.92

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA4797058

Name:
Ethyl 1-(4-(2-oxopyridin-1(2H)-yl)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4Show More⌵

Mol. Formula:
C18H14F3N3O3

M.W.:
377.32

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.22

Polar Surface Area:
66.12

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA4787371

Name:
Ethyl 1-(4-(4-chloro-2-oxopyridin-1(2H)-yl)phenyl)-5-(trifluoromethyl)-1H-pShow More⌵

Mol. Formula:
C18H13ClF3N3O3

M.W.:
411.77

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.87

Polar Surface Area:
66.12

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA4779895

Name:
1-(4-(4-chloro-3-fluoro-2-oxopyridin-1(2H)-yl)phenyl)-N-ethyl-5-(trifluoromShow More⌵

Mol. Formula:
C18H13ClF4N4O2

M.W.:
428.77

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.58

Polar Surface Area:
68.92

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA4763839

Name:
Ethyl 1-(4-(5-chloro-2-oxopyridin-1(2H)-yl)phenyl)-5-(trifluoromethyl)-1H-pShow More⌵

Mol. Formula:
C18H13ClF3N3O3

M.W.:
411.77

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.87

Polar Surface Area:
66.12

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA4762429

Name:
1-(4-(3,4-dichloro-2-oxopyridin-1(2H)-yl)phenyl)-N-ethyl-5-(trifluoromethylShow More⌵

Mol. Formula:
C17H13Cl2F3N4O3S

M.W.:
481.28

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.65

Polar Surface Area:
85.99

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA4761535

Name:
1-(4-(3,4-dichloro-2-oxopyridin-1(2H)-yl)phenyl)-N-ethyl-5-(trifluoromethylShow More⌵

Mol. Formula:
C18H13Cl2F3N4O2

M.W.:
445.23

18 activity values

10 unique targets

Type:
Unknown

AlogP:
4.10

Polar Surface Area:
68.92

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA4741543

Name:
Ethyl 1-(4-(3,5-dichloro-2-oxopyridin-1(2H)-yl)phenyl)-5-(trifluoromethyl)-Show More⌵

Mol. Formula:
C18H12Cl2F3N3O3

M.W.:
446.21

1 activity values

1 unique targets

Type:
Unknown

AlogP:
4.53

Polar Surface Area:
66.12

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

Pyr10

Name:
N-(4-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-4-methylbenzenesulfoShow More⌵

Mol. Formula:
C18H13F6N3O2S

M.W.:
449.38

28 activity values

7 unique targets

Type:
Unknown

AlogP:
5.02

Polar Surface Area:
63.99

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.57

DETAILS