Compounds

ALA5093987

Name:
1-cyclopropyl-6-fluoro-4-oxo-7-(4-(3-oxo-3-(4-(N-pyrimidin-2-ylsulfamoyl)phShow More⌵

Mol. Formula:
C30H30FN7O6S

M.W.:
635.68

4 activity values

4 unique targets

Type:
Unknown

AlogP:
2.92

Polar Surface Area:
166.83

HBA:
10

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5092701

Name:
1-cyclopropyl-6-fluoro-4-oxo-7-(4-(3-oxo-3-(4-sulfamoylphenylamino)propyl)pShow More⌵

Mol. Formula:
C26H28FN5O6S

M.W.:
557.60

4 activity values

4 unique targets

Type:
Unknown

AlogP:
1.97

Polar Surface Area:
155.04

HBA:
8

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA5092628

Name:
1-cyclopropyl-6-fluoro-4-oxo-7-(4-((4-sulfamoylphenyl)diazenyl)piperazin-1-Show More⌵

Mol. Formula:
C23H23FN6O5S

M.W.:
514.54

4 activity values

4 unique targets

Type:
Unknown

AlogP:
2.64

Polar Surface Area:
150.66

HBA:
8

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5090251

Name:
1-cyclopropyl-6-fluoro-4-oxo-7-(4-((4-(N-quinoxalin-2-ylsulfamoyl)phenyl)diShow More⌵

Mol. Formula:
C31H27FN8O5S

M.W.:
642.67

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.74

Polar Surface Area:
162.45

HBA:
10

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA5089465

Name:
1-cyclopropyl-6-fluoro-4-oxo-7-(4-(2-oxo-2-(4-sulfamoylphenylamino)ethyl)piShow More⌵

Mol. Formula:
C25H26FN5O6S

M.W.:
543.58

4 activity values

4 unique targets

Type:
Unknown

AlogP:
1.58

Polar Surface Area:
155.04

HBA:
8

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA5087899

Name:
1-cyclopropyl-6-fluoro-4-oxo-7-(4-(1-oxo-1-(4-(N-quinoxalin-2-ylsulfamoyl)pShow More⌵

Mol. Formula:
C34H32FN7O6S

M.W.:
685.74

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.07

Polar Surface Area:
166.83

HBA:
10

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA5086519

Name:
7-(4-(2-(4-(N-(6-chloropyrazin-2-yl)sulfamoyl)phenylamino)-2-oxoethyl)piperShow More⌵

Mol. Formula:
C29H27ClFN7O6S

M.W.:
656.10

4 activity values

4 unique targets

Type:
Unknown

AlogP:
3.18

Polar Surface Area:
166.83

HBA:
10

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5085647

Name:
1-cyclopropyl-6-fluoro-7-(4-(2-(4-(N-(5-methylisoxazol-3-yl)sulfamoyl)phenyShow More⌵

Mol. Formula:
C29H29FN6O7S

M.W.:
624.65

4 activity values

4 unique targets

Type:
Unknown

AlogP:
3.03

Polar Surface Area:
167.08

HBA:
10

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA5084570

Name:
1-cyclopropyl-6-fluoro-7-(4-((4-(N-(5-methylisoxazol-3-yl)sulfamoyl)phenyl)Show More⌵

Mol. Formula:
C27H26FN7O6S

M.W.:
595.61

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.09

Polar Surface Area:
162.70

HBA:
10

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA5080786

Name:
7-(4-((4-(N-(6-chloropyrazin-2-yl)sulfamoyl)phenyl)diazenyl)piperazin-1-yl)Show More⌵

Mol. Formula:
C27H24ClFN8O5S

M.W.:
627.06

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.24

Polar Surface Area:
162.45

HBA:
10

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA5078898

Name:
1-cyclopropyl-6-fluoro-4-oxo-7-(4-(2-oxo-2-(4-(N-pyrimidin-2-ylsulfamoyl)phShow More⌵

Mol. Formula:
C29H28FN7O6S

M.W.:
621.65

4 activity values

4 unique targets

Type:
Unknown

AlogP:
2.53

Polar Surface Area:
166.83

HBA:
10

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA5076830

Name:
1-cyclopropyl-6-fluoro-4-oxo-7-(4-(1-oxo-1-(4-sulfamoylphenylamino)propan-2Show More⌵

Mol. Formula:
C26H28FN5O6S

M.W.:
557.60

4 activity values

4 unique targets

Type:
Unknown

AlogP:
1.97

Polar Surface Area:
155.04

HBA:
8

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5076468

Name:
1-cyclopropyl-6-fluoro-7-(4-(3-(4-(N-(5-methylisoxazol-3-yl)sulfamoyl)phenyShow More⌵

Mol. Formula:
C30H31FN6O7S

M.W.:
638.68

4 activity values

4 unique targets

Type:
Unknown

AlogP:
3.42

Polar Surface Area:
167.08

HBA:
10

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA5075535

Name:
7-(4-(3-(4-(N-(6-chloropyrazin-2-yl)sulfamoyl)phenylamino)-3-oxopropyl)pipeShow More⌵

Mol. Formula:
C30H29ClFN7O6S

M.W.:
670.12

4 activity values

4 unique targets

Type:
Unknown

AlogP:
3.57

Polar Surface Area:
166.83

HBA:
10

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA5072607

Name:
1-cyclopropyl-6-fluoro-4-oxo-7-(4-((4-(N-pyrimidin-2-ylsulfamoyl)phenyl)diaShow More⌵

Mol. Formula:
C27H25FN8O5S

M.W.:
592.61

4 activity values

4 unique targets

Type:
Unknown

AlogP:
3.59

Polar Surface Area:
162.45

HBA:
10

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.29

DETAILS