Compounds

Type:
Unknown

AlogP:
4.07

Polar Surface Area:
90.13

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.64

DETAILS

ALA4576794

Name:
2-(4-(4-(2-methoxyphenyl)-6,7-dihydro-5H-cyclopenta[d]pyridazin-1-ylamino)pShow More⌵

Mol. Formula:
C22H22N4O2

M.W.:
374.44

5 activity values

Type:
Unknown

AlogP:
3.41

Polar Surface Area:
90.13

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA4575109

Name:
2-(4-(4-(3-methoxyphenyl)phthalazin-1-ylamino)phenyl)acetamide

Mol. Formula:
C23H20N4O2

M.W.:
384.44

Type:
Unknown

AlogP:
4.08

Polar Surface Area:
90.13

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA4572490

Name:
2-(3-(4-(2-methoxyphenyl)-6,7-dihydro-5H-cyclopenta[d]pyridazin-1-ylamino)pShow More⌵

Mol. Formula:
C22H22N4O2

M.W.:
374.44

Type:
Unknown

AlogP:
3.41

Polar Surface Area:
90.13

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA4570366

Name:
2-(3-fluoro-4-(7-(2-(2-(2-methoxyethoxy)ethoxy)phenyl)thieno[2,3-d]pyridaziShow More⌵

Mol. Formula:
C25H25FN4O4S

M.W.:
496.56

Type:
Unknown

AlogP:
4.31

Polar Surface Area:
108.59

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA4557153

Name:
2-(4-(7-(2-methoxyphenyl)thieno[2,3-d]pyridazin-4-ylamino)phenyl)acetamide

Mol. Formula:
C21H18N4O2S

M.W.:
390.47

Type:
Unknown

AlogP:
4.14

Polar Surface Area:
90.13

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA4554497

Name:
3-(4-(4-(2-methoxyphenyl)-6,7-dihydro-5H-cyclopenta[d]pyridazin-1-ylamino)pShow More⌵

Mol. Formula:
C23H24N4O2

M.W.:
388.47

Type:
Unknown

AlogP:
3.80

Polar Surface Area:
90.13

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.64

DETAILS

ALA4550275

Name:
2-(3-fluoro-4-(7-(2-(thiazol-4-ylmethoxy)phenyl)thieno[2,3-d]pyridazin-4-ylShow More⌵

Mol. Formula:
C24H18FN5O2S2

M.W.:
491.57

Type:
Unknown

AlogP:
5.30

Polar Surface Area:
103.02

HBA:
8

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA4548101

Name:
2-(4-(4-(2-methoxyphenyl)-2-methylfuro[3,2-d]pyridazin-7-ylamino)phenyl)aceShow More⌵

Mol. Formula:
C22H20N4O3

M.W.:
388.43

Type:
Unknown

AlogP:
3.98

Polar Surface Area:
103.27

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA4547201

Name:
2-(4-(4,5-diethyl-6-(2-methoxyphenyl)pyridazin-3-ylamino)phenyl)acetamide

Mol. Formula:
C23H26N4O2

M.W.:
390.49

Type:
Unknown

AlogP:
4.05

Polar Surface Area:
90.13

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA4545021

Name:
2-(4-(4-(2-methoxyphenyl)-6,7-dihydro-5H-cyclopenta[d]pyridazin-1-ylamino)-Show More⌵

Mol. Formula:
C23H21F3N4O2

M.W.:
442.44

Type:
Unknown

AlogP:
4.43

Polar Surface Area:
90.13

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA4543380

Name:
2-(2-fluoro-4-(4-(2-methoxyphenyl)-6,7-dihydro-5H-cyclopenta[d]pyridazin-1-Show More⌵

Mol. Formula:
C22H21FN4O2

M.W.:
392.43

Type:
Unknown

AlogP:
3.55

Polar Surface Area:
90.13

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA4539293

Name:
2-(4-(7-(2-(2-(2-(3-tert-butylureido)ethoxy)ethoxy)phenyl)thieno[2,3-d]pyriShow More⌵

Mol. Formula:
C29H33FN6O4S

M.W.:
580.69

Type:
Unknown

AlogP:
4.76

Polar Surface Area:
140.49

HBA:
8

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.18

DETAILS

ALA4529010

Name:
tert-butyl 4-(2-(4-(4-(2-amino-2-oxoethyl)-2-fluorophenylamino)thieno[2,3-dShow More⌵

Mol. Formula:
C29H32FN5O4S

M.W.:
565.67

Type:
Unknown

AlogP:
5.95

Polar Surface Area:
128.46

HBA:
8

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA4527820

Name:
2-(3-methoxy-4-(4-(2-methoxyphenyl)-6,7-dihydro-5H-cyclopenta[d]pyridazin-1Show More⌵

Mol. Formula:
C23H24N4O3

M.W.:
404.47

Type:
Unknown

AlogP:
3.42

Polar Surface Area:
99.36

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA4527007

Name:
2-(4-(4-m-tolylphthalazin-1-ylamino)phenyl)acetamide

Mol. Formula:
C23H20N4O

M.W.:
368.44

Type:
Unknown

AlogP:
4.38

Polar Surface Area:
80.90

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA4525073

Name:
2-(4-(4-(2-methoxyphenyl)furo[3,2-d]pyridazin-7-ylamino)phenyl)acetamide

Mol. Formula:
C21H18N4O3

M.W.:
374.40

Type:
Unknown

AlogP:
3.67

Polar Surface Area:
103.27

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA4475697

Name:
2-(4-(7-(2-methoxyphenyl)furo[2,3-d]pyridazin-4-ylamino)phenyl)acetamide

Mol. Formula:
C21H18N4O3

M.W.:
374.40

Type:
Unknown

AlogP:
3.67

Polar Surface Area:
103.27

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA4469586

Name:
2-(4-(7-(2-((1,4-dioxan-2-yl)methoxy)phenyl)thieno[2,3-d]pyridazin-4-ylaminShow More⌵

Mol. Formula:
C25H23FN4O4S

M.W.:
494.55