Compounds

Type:
Unknown

AlogP:
4.07

Polar Surface Area:
116.68

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA4589525

Name:
(2S,3S)-3-[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)purin-9-yl]bicyclo[2.2Show More⌵

Mol. Formula:
C21H19FN6O2

M.W.:
406.42

Type:
Unknown

AlogP:
3.57

Polar Surface Area:
109.58

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA4580408

Name:
(2S,3S)-3-(5-cyano-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-7H-pyrrolo[2,Show More⌵

Mol. Formula:
C23H19FN6O2

M.W.:
430.44

Type:
Unknown

AlogP:
4.05

Polar Surface Area:
120.48

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA4570851

Name:
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-6,7-dihydrothieno[3,Show More⌵

Mol. Formula:
C22H22FN5O2S

M.W.:
439.52

13 activity values

Type:
Unknown

AlogP:
4.11

Polar Surface Area:
103.79

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA4568323

Name:
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)thieno[2,3-d]pyrimidiShow More⌵

Mol. Formula:
C22H20FN5O2S

M.W.:
437.50

8 activity values

Type:
Unknown

AlogP:
4.68

Polar Surface Area:
103.79

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4567152

Name:
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pteridin-4-yl)amino)bShow More⌵

Mol. Formula:
C22H20FN7O2

M.W.:
433.45

Type:
Unknown

AlogP:
3.40

Polar Surface Area:
129.57

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4567115

Name:
(2S,3S)-3-((6-(difluoromethyl)-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)thShow More⌵

Mol. Formula:
C23H20F3N5O2S

M.W.:
487.51

Type:
Unknown

AlogP:
5.61

Polar Surface Area:
103.79

HBA:
6

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.34

DETAILS

ALA4562249

Name:
(2S,3S)-3-[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrrolo[2,3-d]pyrimidiShow More⌵

Mol. Formula:
C22H20FN5O2

M.W.:
405.43

Type:
Unknown

AlogP:
4.18

Polar Surface Area:
96.69

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA4548835

Name:
(2S,3S)-3-(4-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-methylquinazolin-2-Show More⌵

Mol. Formula:
C25H24FN5O2

M.W.:
445.50

Type:
Unknown

AlogP:
4.92

Polar Surface Area:
103.79

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA4547565

Name:
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)thieno[3,4-d]pyrimidiShow More⌵

Mol. Formula:
C22H20FN5O2S

M.W.:
437.50

10 activity values

Type:
Unknown

AlogP:
4.68

Polar Surface Area:
103.79

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4542293

Name:
(2S,3S)-3-(2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-6H-pyrimido[5,4-b][1,Show More⌵

Mol. Formula:
C22H22FN5O3

M.W.:
423.45

Type:
Unknown

AlogP:
3.25

Polar Surface Area:
104.23

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA4538856

Name:
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5,5-dioxido-6,7-dihyShow More⌵

Mol. Formula:
C22H22FN5O4S

M.W.:
471.51

Type:
Unknown

AlogP:
2.79

Polar Surface Area:
137.93

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA4530239

Name:
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-methylquinazolin-4Show More⌵

Mol. Formula:
C25H24FN5O2

M.W.:
445.50

Type:
Unknown

AlogP:
4.92

Polar Surface Area:
103.79

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA4529778

Name:
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-7H-pyrrolo[2,3-d]pyrShow More⌵

Mol. Formula:
C22H21FN6O2

M.W.:
420.45

Type:
Unknown

AlogP:
3.94

Polar Surface Area:
119.58

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4527175

Name:
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5,6,7,8-tetrahydroquShow More⌵

Mol. Formula:
C24H26FN5O2

M.W.:
435.50

Type:
Unknown

AlogP:
4.34

Polar Surface Area:
103.79

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA4524775

Name:
(2S,3S)-3-((7-fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrido[3,2-dShow More⌵

Mol. Formula:
C23H20F2N6O2

M.W.:
450.45

Type:
Unknown

AlogP:
4.15

Polar Surface Area:
116.68

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4522400

Name:
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-7-methylpyrido[3,2-dShow More⌵

Mol. Formula:
C24H23FN6O2

M.W.:
446.49

Type:
Unknown

AlogP:
4.32

Polar Surface Area:
116.68

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA4519832

Name:
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-6,6-dioxido-5,7-dihyShow More⌵

Mol. Formula:
C22H22FN5O4S

M.W.:
471.51

Type:
Unknown

AlogP:
2.89

Polar Surface Area:
137.93

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA4514982

Name:
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrido[3,2-d]pyrimidiShow More⌵

Mol. Formula:
C23H21FN6O2

M.W.:
432.46

Type:
Unknown

AlogP:
4.01

Polar Surface Area:
116.68

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4513835

Name:
(2S,3S)-3-(5-fluoro-2-(5-fluoro-1H-indol-3-yl)pyrimidin-4-ylamino)bicyclo[2Show More⌵

Mol. Formula:
C21H20F2N4O2

M.W.:
398.41