Compounds

Type:
Unknown

AlogP:
5.33

Polar Surface Area:
114.05

HBA:
7

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA4649871

Name:
2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-ethyl-5,6,7,8-tetrahydropyridoShow More⌵

Mol. Formula:
C29H33N7O2

M.W.:
511.63

Type:
Unknown

AlogP:
4.56

Polar Surface Area:
108.06

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.30

DETAILS

ALA4649211

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-isopropyl-5,6,7,8-tetrahydropyShow More⌵

Mol. Formula:
C31H37N7O2

M.W.:
539.68

Type:
Unknown

AlogP:
5.19

Polar Surface Area:
108.06

HBA:
7

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA4649021

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-5,7-dihydrofuro[3,4-d]pyrimidin-Show More⌵

Mol. Formula:
C26H24N6O3

M.W.:
468.52

Type:
Unknown

AlogP:
3.96

Polar Surface Area:
114.05

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA4648189

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-(1-methylcyclopropyl)-5,6,7,8-Show More⌵

Mol. Formula:
C31H35N7O2

M.W.:
537.67

Type:
Unknown

AlogP:
5.09

Polar Surface Area:
108.06

HBA:
7

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA4647586

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-methyl-5,6,7,8-tetrahydropyridShow More⌵

Mol. Formula:
C30H35N7O2

M.W.:
525.66

Type:
Unknown

AlogP:
4.95

Polar Surface Area:
108.06

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA4647311

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-7,8-dihydro-5H-pyrano[4,3-d]pyriShow More⌵

Mol. Formula:
C28H30N6O3

M.W.:
498.59

Type:
Unknown

AlogP:
4.64

Polar Surface Area:
114.05

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.34

DETAILS

ALA4645739

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-5,7-dihydrofuro[3,4-d]pyrimidin-Show More⌵

Mol. Formula:
C27H28N6O3

M.W.:
484.56

Type:
Unknown

AlogP:
4.55

Polar Surface Area:
105.26

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA4645662

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-cyclopropyl-5,6,7,8-tetrahydroShow More⌵

Mol. Formula:
C30H33N7O2

M.W.:
523.64

6 activity values

Type:
Unknown

AlogP:
4.70

Polar Surface Area:
108.06

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA4645036

Name:
2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-cyclopropyl-5,6,7,8-tetrahydroShow More⌵

Mol. Formula:
C31H33N7O2

M.W.:
535.65

Type:
Unknown

AlogP:
4.85

Polar Surface Area:
108.06

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA4642809

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-cyclobutyl-5,6,7,8-tetrahydropShow More⌵

Mol. Formula:
C31H35N7O2

M.W.:
537.67

Type:
Unknown

AlogP:
5.09

Polar Surface Area:
108.06

HBA:
7

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA4642046

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-(1-methoxypropan-2-yl)-5,6,7,8Show More⌵

Mol. Formula:
C32H39N7O3

M.W.:
569.71

Type:
Unknown

AlogP:
4.96

Polar Surface Area:
117.29

HBA:
8

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA4641999

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-ethyl-5,6,7,8-tetrahydropyridoShow More⌵

Mol. Formula:
C30H35N7O2

M.W.:
525.66

Type:
Unknown

AlogP:
4.95

Polar Surface Area:
108.06

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.30

DETAILS

ALA4640792

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-isopropyl-5,6,7,8-tetrahydropyShow More⌵

Mol. Formula:
C30H35N7O2

M.W.:
525.66

Type:
Unknown

AlogP:
4.95

Polar Surface Area:
108.06

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA4638556

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-isopropyl-5,6,7,8-tetrahydropyShow More⌵

Mol. Formula:
C32H37N7O2

M.W.:
551.70

Type:
Unknown

AlogP:
5.48

Polar Surface Area:
108.06

HBA:
7

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA4638542

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-(2-methoxyethyl)-5,6,7,8-tetraShow More⌵

Mol. Formula:
C31H37N7O3

M.W.:
555.68

Type:
Unknown

AlogP:
4.58

Polar Surface Area:
117.29

HBA:
8

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA4638502

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-methyl-5,6,7,8-tetrahydropyridShow More⌵

Mol. Formula:
C29H33N7O2

M.W.:
511.63

Type:
Unknown

AlogP:
4.56

Polar Surface Area:
108.06

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.33

DETAILS

ALA4638234

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-5,7-dihydrofuro[3,4-d]pyrimidin-Show More⌵

Mol. Formula:
C27H26N6O3

M.W.:
482.54

Type:
Unknown

AlogP:
4.36

Polar Surface Area:
114.05

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.34

DETAILS

ALA4637311

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-methyl-5,6,7,8-tetrahydropyridShow More⌵

Mol. Formula:
C29H31N7O2

M.W.:
509.61

Type:
Unknown

AlogP:
4.31

Polar Surface Area:
108.06

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.32

DETAILS

ALA4637262

Name:
2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-5,6,7,8-tetrahydropyrido[4,3-d]pShow More⌵

Mol. Formula:
C27H29N7O2

M.W.:
483.58