Compounds

Type:
---

AlogP:
2.16

Polar Surface Area:
105.17

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA5205521

Name:
5-{[3-(Methanesulfonyl)phenyl]methoxy}-2-(1H-pyrazol-5-yl)pyridine

Mol. Formula:
C16H15N3O3S

M.W.:
329.38

Type:
---

AlogP:
2.45

Polar Surface Area:
84.94

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5203135

Name:
N-{(1R,4R)-4-[({6-[1-(Oxan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl}oxy)methyl]cyShow More⌵

Mol. Formula:
C17H22N4O2

M.W.:
314.39

Type:
---

AlogP:
2.55

Polar Surface Area:
79.90

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA5199278

Name:
5-{[(3R)-1-(Methanesulfonyl)piperidin-3-yl]methoxy}-2-(1H-pyrazol-5-yl)pyriShow More⌵

Mol. Formula:
C15H20N4O3S

M.W.:
336.42

Type:
---

AlogP:
1.52

Polar Surface Area:
88.18

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA5199197

Name:
Cyclopropyl[4-({[6-(1H-pyrazol-5-yl)pyridin-3-yl]oxy}methyl)piperidin-1-yl]Show More⌵

Mol. Formula:
C18H22N4O2

M.W.:
326.40

Type:
---

AlogP:
2.50

Polar Surface Area:
71.11

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.92

DETAILS

ALA5195609

Name:
5-{[1-(Methanesulfonyl)piperidin-4-yl]methoxy}-2-(1H-pyrazol-5-yl)pyridine

Mol. Formula:
C15H20N4O3S

M.W.:
336.42

Type:
---

AlogP:
1.52

Polar Surface Area:
88.18

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA5195431

Name:
5-{[4-(Methanesulfonyl)phenyl]methoxy}-2-(1H-pyrazol-5-yl)pyridine

Mol. Formula:
C16H15N3O3S

M.W.:
329.38

Type:
---

AlogP:
2.45

Polar Surface Area:
84.94

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5195099

Name:
4-({[6-(1H-Pyrazol-5-yl)pyridin-3-yl]oxy}methyl)benzonitrile

Mol. Formula:
C16H12N4O

M.W.:
276.30

Type:
---

AlogP:
2.92

Polar Surface Area:
74.59

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5192567

Name:
1-[(3R)-3-({[6-(1H-Pyrazol-5-yl)pyridin-3-yl]oxy}methyl)piperidin-1-yl]ethaShow More⌵

Mol. Formula:
C16H20N4O2

M.W.:
300.36

Type:
---

AlogP:
2.11

Polar Surface Area:
71.11

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.94

DETAILS

ALA5192170

Name:
5-[2-(4-Methyl-1,3-thiazol-5-yl)ethoxy]-2-(1H-pyrazol-5-yl)pyridine

Mol. Formula:
C14H14N4OS

M.W.:
286.36

Type:
---

AlogP:
2.86

Polar Surface Area:
63.69

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5191778

Name:
1-[(3S)-3-({[6-(1H-Pyrazol-5-yl)pyridin-3-yl]oxy}methyl)piperidin-1-yl]ethaShow More⌵

Mol. Formula:
C16H20N4O2

M.W.:
300.36

Type:
---

AlogP:
2.11

Polar Surface Area:
71.11

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.94

DETAILS

ALA5189943

Name:
5-{[(3S)-1-(Methanesulfonyl)piperidin-3-yl]methoxy}-2-(1H-pyrazol-5-yl)pyriShow More⌵

Mol. Formula:
C15H20N4O3S

M.W.:
336.42

Type:
---

AlogP:
1.52

Polar Surface Area:
88.18

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA5184859

Name:
N-[(1S,4S)-4-({[6-(1H-Pyrazol-5-yl)pyridin-3-yl]oxy}methyl)cyclohexyl]acetaShow More⌵

Mol. Formula:
C17H22N4O2

M.W.:
314.39

Type:
---

AlogP:
2.55

Polar Surface Area:
79.90

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA5183418

Name:
3-({[6-(1H-Pyrazol-5-yl)pyridin-3-yl]oxy}methyl)benzonitrile

Mol. Formula:
C16H12N4O

M.W.:
276.30

Type:
---

AlogP:
2.92

Polar Surface Area:
74.59

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5183091

Name:
Methyl 4-({[6-(1H-pyrazol-5-yl)pyridin-3-yl]oxy}methyl)piperidine-1-carboxyShow More⌵

Mol. Formula:
C16H20N4O3

M.W.:
316.36

Type:
---

AlogP:
2.33

Polar Surface Area:
80.34

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.94

DETAILS

ALA5182293

Name:
1-(4-{[6-(1H-Pyrazol-5-yl)pyridin-3-yl]oxy}piperidin-1-yl)ethan-1-one

Mol. Formula:
C15H18N4O2

M.W.:
286.33

Type:
---

AlogP:
1.86

Polar Surface Area:
71.11

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.93

DETAILS

ALA5181516

Name:
1-[(3S)-3-{[6-(1H-Pyrazol-5-yl)pyridin-3-yl]oxy}piperidin-1-yl]ethan-1-one

Mol. Formula:
C15H18N4O2

M.W.:
286.33

Type:
---

AlogP:
1.86

Polar Surface Area:
71.11

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.93

DETAILS

ALA5180285

Name:
5-[2-(4-Methyl-1,3-thiazol-5-yl)ethoxy]-2-(1H-pyrazol-5-yl)pyrimidine

Mol. Formula:
C13H13N5OS

M.W.:
287.35

Type:
---

AlogP:
2.25

Polar Surface Area:
76.58

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5174407

Name:
N,N-Dimethyl-4-({[6-(1H-pyrazol-5-yl)pyridin-3-yl]oxy}methyl)piperidine-1-cShow More⌵

Mol. Formula:
C17H23N5O2

M.W.:
329.40

Type:
---

AlogP:
2.24

Polar Surface Area:
74.35

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.93

DETAILS

ALA5173608

Name:
5-[(4-Fluorophenyl)methoxy]-2-(1H-pyrazol-5-yl)pyridine

Mol. Formula:
C15H12FN3O

M.W.:
269.28