Compounds

ALA5266462

Name:

Mol. Formula:
C26H31NO3

M.W.:
405.54

Type:
---

AlogP:
4.05

Polar Surface Area:
49.77

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5282085

Name:
(S)-2-((3,4-difluorophenoxy)methyl)-4-((1-methyl-1H-indazol-5-yl)methyl)morShow More⌵

Mol. Formula:
C20H21F2N3O2

M.W.:
373.40

Type:
---

AlogP:
3.13

Polar Surface Area:
39.52

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5280960

Name:
2-((4-((6-methylpyridin-2-yl)methoxy)piperidin-1-yl)methyl)imidazo[1,2-a]pyShow More⌵

Mol. Formula:
C20H24N4O

M.W.:
336.44

Type:
---

AlogP:
3.22

Polar Surface Area:
42.66

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA5280610

Name:

Mol. Formula:
C26H31NO3

M.W.:
405.54

Type:
---

AlogP:
4.05

Polar Surface Area:
49.77

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5279686

Name:
(S)-4-((1-methyl-1H-indazol-5-yl)methyl)-2-(((4-methylthiazol-2-yl)oxy)methShow More⌵

Mol. Formula:
C18H22N4O2S

M.W.:
358.47

Type:
---

AlogP:
2.62

Polar Surface Area:
52.41

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5279538

Name:

Mol. Formula:
C19H27NO

M.W.:
285.43

Type:
---

AlogP:
3.88

Polar Surface Area:
23.47

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA5276035

Name:

Mol. Formula:
C26H31NO3

M.W.:
405.54

Type:
---

AlogP:
4.05

Polar Surface Area:
49.77

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5274616

Name:
3-(1-(3-phenylpropyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyriShow More⌵

Mol. Formula:
C21H23N3

M.W.:
317.44

Type:
---

AlogP:
4.28

Polar Surface Area:
31.92

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5274285

Name:
6-chloro-2-((1-(3,4-difluorobenzyl)-1,7-diazaspiro[4.4]nonan-7-yl)methyl)-1Show More⌵

Mol. Formula:
C23H24ClF2N3

M.W.:
415.92

Type:
---

AlogP:
5.34

Polar Surface Area:
22.27

HBA:
2

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA5274252

Name:

Mol. Formula:
C26H30ClNO3

M.W.:
439.98

Type:
---

AlogP:
4.70

Polar Surface Area:
49.77

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5273358

Name:
(S)-6-(((1-hydroxy-2-methyl-1-phenylpropan-2-yl)amino)methyl)-1-methyl-3,4-Show More⌵

Mol. Formula:
C21H26N2O2

M.W.:
338.45

Type:
---

AlogP:
3.20

Polar Surface Area:
52.57

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.88

DETAILS

ALA5290749

Name:
N-(3-chloro-2-methylphenyl)-2-(1-(3,4-difluorobenzyl)-1,8-diazaspiro[4.5]deShow More⌵

Mol. Formula:
C24H28ClF2N3O

M.W.:
447.96

Type:
---

AlogP:
5.00

Polar Surface Area:
35.58

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5289958

Name:
6-chloro-2-((7-(3,4-difluorobenzyl)-2,7-diazaspiro[4.5]decan-2-yl)methyl)-1Show More⌵

Mol. Formula:
C24H26ClF2N3

M.W.:
429.94

Type:
---

AlogP:
5.59

Polar Surface Area:
22.27

HBA:
2

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA5288366

Name:
N-(3-chloro-2-methylphenyl)-2-(1-(3,4-difluorobenzyl)-1,7-diazaspiro[4.4]noShow More⌵

Mol. Formula:
C23H26ClF2N3O

M.W.:
433.93

Type:
---

AlogP:
4.61

Polar Surface Area:
35.58

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.75

DETAILS

ALA5288298

Name:
2-(1-(3,4-difluorobenzyl)-1,7-diazaspiro[4.4]nonan-7-yl)-N-(4-fluoro-3-methShow More⌵

Mol. Formula:
C23H26F3N3O

M.W.:
417.48

Type:
---

AlogP:
4.09

Polar Surface Area:
35.58

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA5287836

Name:
(S)-3-((3-fluoro-4-methoxybenzyl)oxy)-1-(4-methylbenzyl)piperidine

Mol. Formula:
C21H26FNO2

M.W.:
343.44

Type:
---

AlogP:
4.32

Polar Surface Area:
21.70

HBA:
3

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5286047

Name:
(S)-1-methyl-5-((3-((2-methylbenzyl)oxy)piperidin-1-yl)methyl)-1H-indazole

Mol. Formula:
C22H27N3O

M.W.:
349.48

Type:
---

AlogP:
4.06

Polar Surface Area:
30.29

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5286004

Name:
(S)-1-methyl-5-((3-((6-methylpyridin-2-yl)methoxy)piperidin-1-yl)methyl)-1HShow More⌵

Mol. Formula:
C21H26N4O

M.W.:
350.47

Type:
---

AlogP:
3.46

Polar Surface Area:
43.18

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5285555

Name:
N-(3-chloro-2-methylphenyl)-2-(7-(3,4-difluorobenzyl)-2,7-diazaspiro[4.5]deShow More⌵

Mol. Formula:
C24H28ClF2N3O

M.W.:
447.96

Type:
---

AlogP:
4.85

Polar Surface Area:
35.58

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5316208

Name:

Mol. Formula:
C20H29NO

M.W.:
299.46

Type:
---

AlogP:
4.27

Polar Surface Area:
23.47

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.65

DETAILS