Compounds

Type:
Unknown

AlogP:
4.26

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA4799902

Name:
N-[4-(1,3-dioxoisoindolin-2-yl)-2,3,6-trifluorophenyl]-3-methylfuran-2-carbShow More⌵

Mol. Formula:
C20H11F3N2O4

M.W.:
400.31

Type:
Unknown

AlogP:
4.06

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.53

DETAILS

ALA4798021

Name:
N-[4-(4-chloro-1,3-dioxo-isoindolin-2-yl)-5-fluoro-2-methylphenyl]-3-methylShow More⌵

Mol. Formula:
C21H14ClFN2O4

M.W.:
412.80

Type:
Unknown

AlogP:
4.74

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA4797971

Name:
5-chloro-N-[4-(1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl)-5-fluoro-2-methylShow More⌵

Mol. Formula:
C20H16ClFN2O4

M.W.:
402.81

5 activity values

Type:
Unknown

AlogP:
4.38

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA4796783

Name:
N-[4-(1,3-dioxoisoindolin-2-yl)-2,5-difluorophenyl]-3-methylfuran-2-carboxaShow More⌵

Mol. Formula:
C20H12F2N2O4

M.W.:
382.32

Type:
Unknown

AlogP:
3.92

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA4795522

Name:
N-[4-(5-chloro-1,3-dioxo-isoindolin-2-yl)-2,3,6-trifluorophenyl]-3-methylfuShow More⌵

Mol. Formula:
C20H10ClF3N2O4

M.W.:
434.76

Type:
Unknown

AlogP:
4.71

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4795139

Name:
N-[4-(1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl)-5-fluoro-2-methylphenyl]-2Show More⌵

Mol. Formula:
C20H18FN3O3S

M.W.:
399.45

5 activity values

Type:
Unknown

AlogP:
3.90

Polar Surface Area:
79.37

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA4792152

Name:
N-[4-(1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl)-5-fluoro-2-methylphenyl]-3Show More⌵

Mol. Formula:
C21H19FN2O4

M.W.:
382.39

8 activity values

4 unique targets

Type:
Unknown

AlogP:
4.03

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA4789952

Name:
3-methyl-N-[2,3,6-trifluoro-4-(5-fluoro-1,3-dioxo-isoindolin-2-yl)phenyl]fuShow More⌵

Mol. Formula:
C20H10F4N2O4

M.W.:
418.30

Type:
Unknown

AlogP:
4.20

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4788523

Name:
N-[4-(5-chloro-1,3-dioxoisoindolin-2-yl)-5-fluoro-2-methylphenyl]-3-methylfShow More⌵

Mol. Formula:
C21H14ClFN2O4

M.W.:
412.80

Type:
Unknown

AlogP:
4.74

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA4787147

Name:
N-[4-(6,6-dimethyl-2,4-dioxo-3-azabicyclo[3.1.0]hexan-3-yl)phenyl]pyridine-Show More⌵

Mol. Formula:
C19H17N3O3

M.W.:
335.36

1 activity values

Type:
Unknown

AlogP:
2.48

Polar Surface Area:
79.37

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.87

DETAILS

ALA4787053

Name:
N-[4-(4-chloro-1,3-dioxoisoindolin-2-yl)-2,3,5-trifluorophenyl]-3-methylfurShow More⌵

Mol. Formula:
C20H10ClF3N2O4

M.W.:
434.76

8 activity values

4 unique targets

Type:
Unknown

AlogP:
4.71

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4782646

Name:
N-[4-(5-chloro-1,3-dioxoisoindolin-2-yl)-2,3,5-trifluorophenyl]-3-methylfurShow More⌵

Mol. Formula:
C20H10ClF3N2O4

M.W.:
434.76

Type:
Unknown

AlogP:
4.71

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4780280

Name:
N-[4-(1,3-dioxoisoindolin-2-yl)-5-fluoro-2-methylphenyl]-3-methylfuran-2-caShow More⌵

Mol. Formula:
C21H15FN2O4

M.W.:
378.36

Type:
Unknown

AlogP:
4.09

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA4779008

Name:
N-[4-(1,3-dioxoisoindolin-2-yl)-2,6-difluorophenyl]-3-methylfuran-2-carboxaShow More⌵

Mol. Formula:
C20H12F2N2O4

M.W.:
382.32

Type:
Unknown

AlogP:
3.92

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA4777502

Name:
N-[5-fluoro-2-methyl-4-(5-methyl-1,3-dioxoisoindolin-2-yl)phenyl]-3-methylfShow More⌵

Mol. Formula:
C22H17FN2O4

M.W.:
392.39

Type:
Unknown

AlogP:
4.40

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA4764083

Name:
N-[5-fluoro-4-(4-fluoro-1,3-dioxo-isoindolin-2-yl)-2-methylphenyl]-3-methylShow More⌵

Mol. Formula:
C21H14F2N2O4

M.W.:
396.35

Type:
Unknown

AlogP:
4.23

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA4763120

Name:
N-[4-(1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl)-2,3,6-trifluorophenyl]-3-mShow More⌵

Mol. Formula:
C20H15F3N2O4

M.W.:
404.34

Type:
Unknown

AlogP:
4.00

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA4760570

Name:
N-[4-(1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl)-5-fluoro-2-methylphenyl]fuShow More⌵

Mol. Formula:
C20H17FN2O4

M.W.:
368.36

5 activity values

Type:
Unknown

AlogP:
3.72

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.84

DETAILS

ALA4757473

Name:
Pyridine-2-carboxylic acid [4-((1R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.0(2,6Show More⌵

Mol. Formula:
C21H17N3O3

M.W.:
359.39

1 activity values